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Mashup Score: 3Lnc-ing epicardium-derived cells to cardiac remodelling: lncRNA-TARID as a novel antifibrotic option - 1 year(s) ago
This editorial refers to ‘Intrapericardial long non-coding RNA–Tcf21 antisense RNA inducing demethylation administration promotes cardiac repair’, by D. Zhu et
Source: OUP AcademicCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 2Emerging epigenetic therapies of cardiac fibrosis and remodelling in heart failure: from basic mechanisms to early clinical development - 1 year(s) ago
Abstract. Cardiovascular diseases and specifically heart failure (HF) impact global health and impose a significant economic burden on society. Despite current
Source: OUP AcademicCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Long non-coding RNAs: definitions, functions, challenges and recommendations - Nature Reviews Molecular Cell Biology - 1 year(s) ago
This Consensus Statement addresses the definition, nomenclature and classification of long non-coding RNAs, and provides a shared viewpoint on their features and functions. The authors also discuss research challenges and provide recommendations to advance our understanding of long non-coding RNAs.
Source: NatureCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0LncRNA Airn maintains LSEC differentiation to alleviate liver fibrosis via the KLF2-eNOS-sGC pathway - BMC Medicine - 2 year(s) ago
Background Long noncoding RNAs (lncRNAs) have emerged as important regulators in a variety of human diseases. The dysregulation of liver sinusoidal endothelial cell (LSEC) phenotype is a critical early event in the fibrotic process. However, the biological function of lncRNAs in LSEC still remains unclear. Methods The expression level of lncRNA Airn was evaluated in both human fibrotic livers and…
Source: BioMed CentralCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 2Upregulation of lncRNA PINK1-AS Predicts the Distant Metastasis of Patients with Small Cell Lung Cancer - PubMed - 2 year(s) ago
PINK1-AS has been shown to participate in gastric cancer, while its role in other tumors is unclear. This study was carried out to explore the participation of PINK1-AS in small cell lung cancer (SCLC). In this study, the expression of PINK1-AS in SCLC and paired non-cancer tissues from 60 SCLC pati …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 6Orna Issler - 2 year(s) ago
Icahn School of Medicine at mount sinai – Cited by 2,620 – Neuroscience
Source: scholar.google.co.ilCategories: Latest Headlines, NeurologyTweet-
THANK YOU @exRNA for highlighting @IsslerOrna's work on "Sex-Specific Role for the Long Non-coding RNA LINC00473 in #Depression"! CHECK OUT Dr. Issler's other publications here👉 https://t.co/ZnRSvndczN #NestlerLab #CREB #lncRNA #sexdifferences @EricJNestler https://t.co/BNgg8HseFa https://t.co/ViAOIFdNEE
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Mashup Score: 6
Objective To better comprehend transcriptional phenotypes of cancer cells, we globally characterised RNA-binding proteins (RBPs) to identify altered RNAs, including long non-coding RNAs (lncRNAs). Design To unravel RBP-lncRNA interactions in cancer, we curated a list of ~2300 highly expressed RBPs in human cells, tested effects of RBPs and lncRNAs on patient survival in multiple cohorts, altered…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 5
Objective To better comprehend transcriptional phenotypes of cancer cells, we globally characterised RNA-binding proteins (RBPs) to identify altered RNAs, including long non-coding RNAs (lncRNAs). Design To unravel RBP-lncRNA interactions in cancer, we curated a list of ~2300 highly expressed RBPs in human cells, tested effects of RBPs and lncRNAs on patient survival in multiple cohorts, altered…
Source: GutCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 8Long Noncoding RNA lncNDEPD1 Regulates PD-1 Expression via miR-3619-5p in CD8+ T Cells - 2 year(s) ago
Therapies targeting programmed cell death protein 1 (PD-1) have gained great success in patients with multiple types of cancer. The regulatory mechanisms underlying PD-1 expression have been extensively explored. However, the impact of long noncoding RNAs on PD-1 expression remains elusive. In this
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 1
Background: Ku70 participates in several pathological processes through mediating repair of DNA double-strand breaks. Our previous study has identified a highly conserved long noncoding RNA cardiac i
Source: Circulation ResearchCategories: Cardiology News and Journals, Latest HeadlinesTweet
Lnc-ing epicardium-derived cells to cardiac remodelling: lncRNA-TARID as a novel antifibrotic option. https://t.co/ZOP7WFkEjO #lncRNA #fibrosis #myocardium #cardiotwitter @escardio @ESC_Journals https://t.co/A3AACVR6pk