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Mashup Score: 0Top Reads - 6 hour(s) ago
Transcriptional Dynamics of CL Lesions during Treatment See article p. 8942DG and CAR T Cells for Cancer Immunotherapy See article p. 917
Source: journals.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 1The Journal of Immunology - 9 hour(s) ago
Read Volume 212 Issue 3 of The Journal of Immunology.
Source: journals.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
#ICYMI The JI February 1 issue is now available! #Immunology #ReadtheJI https://t.co/snsD5mYcXF This issue: 💥#PillarsofImmunology – Tim3’s discovery 💥#BriefReview – Guardians of the Tissue 💪 💥#CuttingEdge – pDC #ImmuneRegulation #COVID19 #Cancer #Infection https://t.co/P43HzjAVjk
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Mashup Score: 1The Foot-and-Mouth Disease Virus Lb Protease Cleaves Intracellular Transcription Factors STAT1 and STAT2 to Antagonize IFN-β–Induced Signaling - 11 hour(s) ago
Key Points. FMDV leader protease inhibits IFN-β–induced innate immune response.FMDV Lpro interacts with STAT1/2 to cleave STAT1/2 through protease activity.252–
Source: journals.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
The Lb #protease of #FootandMouthDisease virus cleaves #STAT1 and #STAT2 to impeded #IFNbeta-induced antiviral signaling | from HaiXue Zheng at Lanzhou Veterinary Research Institute | #ReadTheJI #generegulation #immunology 👉 https://t.co/ZtrplJBTWe https://t.co/ZHOORo9fQq
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Mashup Score: 14Pillars of Immunology | The Journal of Immunology | American Association of Immunologists - 13 hour(s) ago
The Journal of Immunology publishes commentaries highlighting scientific reports that were published more than 15 years ago and that have made a major
Source: journals.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
#DYK about The JI’s #PillarsofImmunology? This commentary series highlights #immunology studies (published >15y ago) that provide a foundation for the #research of today. Learn about the pillars that have fueled the work you do! #ReadtheJI https://t.co/yfcIXngAyC https://t.co/xHFe4PolQo
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Mashup Score: 90Life In-Between: Bridging Innate and Adaptive Immunity | American Association of Immunologists - 28 day(s) ago
This collection features Guest Editor Sebastian Joyce and covers the complex interaction between innate and adaptive immunity.
Source: journals.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Get up-to-date on mechanisms that bridge #ImmuneSystem arms. Dr. Sebastian Joyce guest edits this special collection that highlights the complex immune circuits that impact innate & adaptive immunity. Check it out! #ReadTheJI #ICYMI #ILCs ➡️ https://t.co/o1dWOn90Am https://t.co/HbyQZGlawg
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Mashup Score: 21Cutting Edge: ATP13A2 Is an Endolysosomal Regulator of TLR9/7 Activation in Human Plasmacytoid Dendritic Cells - 29 day(s) ago
Key Points. Human pDCs express ATP13A2 in their endolysosomal compartments.ATP13A2-mediated polyamine transport regulates TLR9/7 activation in pDCs.ATP13A2
Source: journals.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
This 🚨#CuttingEdge 🚨 study reveals the role of an ATPase in regulating plasmacytoid DCs. Check it out #immunology #ReadTheJI https://t.co/uTaly6xLG4 https://t.co/l8ts2iiAIr
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Mashup Score: 7
Key Points. HD IL-2 promotes effector lymphocytes (CD8+ and NK cells) extravasation and expansion.B cells undergo oligoclonal expansion during HD IL-2 ther
Source: journals.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
#ICYMI 📢 This #human #clinical retrospective study evaluates patients with #RenalCellCarcinoma #cancer #metastasis treated with high-dose IL2. Read about the study & find out the impact on immune cells here #ReadTheJI: https://t.co/aARbq7Doo5 https://t.co/Ko67n8PJug
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Mashup Score: 1N-Glycan Branching Regulates BTLA Opposite to PD-1 to Limit T Cell Hyperactivity Induced by Branching Deficiency - 2 month(s) ago
Key Points. N-glycan branching enhances PD-1 cell surface expression by inhibiting PD-1 endocytosis.N-glycan branching inhibits BTLA cell surface expressio
Source: journals.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
The impact of N-glycan branching on inhibitory receptor expression is investigated and differential effects on BTLA and PD-1 are revealed. Check out how these opposing effects act to regulate responses: https://t.co/9AzlpBVghU. #ReadTheJI #immunology https://t.co/LdcP7yecl8
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Mashup Score: 5Challenges in the Development of NK-92 Cells as an Effective Universal Off-the-Shelf Cellular Therapeutic - 2 month(s) ago
Key Points. Some cancer patients exhibit pre-existing IgM recognition of NK-92 and CAR-NK92 cells.Repeat infusions of CAR-NK92 cells to tumor patients led
Source: journals.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Challenges in developing off-the-shelf #immunotherapy using CAR-NK92 cells are highlighted. Learn how these cells could be optimized to improve efficacy: https://t.co/hmfnUGdo3I. #ReadTheJI #immunology https://t.co/X8Ci083yIV
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Mashup Score: 50Circulating Immune Cells from Early- and Late-onset Pre-eclampsia Displays Distinct Profiles with Differential Impact on Endothelial Activation - 2 month(s) ago
Key Points. EOPE PBMCs exhibit enhanced cell activation pathways and proinflammatory phenotypes, contributing to endothelial activation in vitro.LOPE shows
Source: journals.aai.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
This study investigates maternal systemic immune responses during early and late pre-eclampsia. Discover how these responses differentially impact endothelial cell activation when compared to those during an uncomplicated pregnancy: https://t.co/GLR0fB4eEX. #ReadTheJI #immunology https://t.co/V9qF3HmJVN
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The #JI_TopRead summaries are #FreeToRead and are meant to help keep you up to date on some of the hottest #immunology research in every issue of #TheJI. 👉 https://t.co/lCjrD8j8iK https://t.co/dWexd13qFq