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There’s no such thing as a dog that can’t cause...

Mashup Score:101

Immunity

Macrophages in the gastrointestinal tract occupy different anatomic niches, where they are exposed to a variety of environmental cues and perform niche-specific functions. In...

Mashup Score:70

Immunity

Recent years have seen a transformation in our understanding of lung macrophage heterogeneity and functional diversity. In this review, Jakubzick and colleagues unpack the...

Mashup Score:56

Immunity

Hepatic macrophages are more heterogeneous than once thought. In this perspective, Guilliams and Scott discuss what is currently known regarding the distinct macrophage populations,...

The functional basis of tolerance to the gut microbiome is incompletely understood. Pedersen et al. develop an antigen-discovery approach to assess microbiota-directed T cell immunity in...

(Immunity 49, 1148–1161.e1–e7; December 18,...

During immune responses, B cells generate functionally diverse secreted antibodies through cellular differentiation and class switch recombination. Horton et al. reveal that distinct clonal mechanisms...

Epinephrine is the only effective treatment for anaphylaxis but studies routinely show underutilization. This is especially troubling given the fact that fatal anaphylaxis has...

Traditionally viewed as poorly plastic, neutrophils are now recognized as functionally diverse; however, the extent and determinants of neutrophil heterogeneity in humans remain unclear....