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Mashup Score:122

Nature

γδ T cells mediate immunotherapy responses when cancers lack MHC class I – Nature Reviews Immunology - 5 days

Mashup Score:122

γδ T cells are important for responding to immune checkpoint blockade therapy in patients whose cancers have downregulated MHC class I...

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Mashup Score:98

Nature

The role of platelets in immune-mediated inflammatory diseases – Nature Reviews Immunology - 1 week

Mashup Score:98

In addition to their well-established role in haemostasis, platelets also have an active role in the immune response. Here the authors summarize the evidence...

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Mashup Score:92

Science Immunology

Contents | Science Immunology 8, 80 - 22 hours

Mashup Score:92

Science Immunology Volume 8|Issue 80|Feb 2023 ONLINE COVER Tumor-infiltrating Lymphocytes on JET Patrol. This month’s cover depicts T lymphocytes specific for tumor neoantigens near...

More coverage: #cancer #immunology
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Mashup Score:37

Immunity

Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer - 5 days

Mashup Score:37

How tissue-specific mechanisms shape anti-tumor immunity remains poorly understood. Zagorulya et al. reveal that lung lymph node (LN)-specific abundance of interferon-gamma induces suppressive Th1-like effector...

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Mashup Score:36

Nature

Regulation of ribosomal RNA gene copy number, transcription and nucleolus organization in eukaryotes – Nature Reviews Molecular Cell Biology - 5 days

Mashup Score:36

Ribosome biogenesis, including ribosomal RNA (rRNA) production, occurs in the nucleolus. Recent studies have revealed how the integrity and copy number of rRNA genes...

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Mashup Score:29

Immunity

Single-cell and spatial transcriptomics reveal aberrant lymphoid developmental programs driving granuloma formation - 14 hours

Mashup Score:29

Granulomas are accumulations of immune cells that help contain infections but can also give rise to diseases. To better understand granuloma formation, Krausgruber et al....

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Mashup Score:15

American Association of Immunologists

Restored Thymic Output after Androgen Blockade Participates in Antitumor Immunity - 1 day

Mashup Score:15

Key Points. Androgen deprivation therapy results in increased recent thymic emigrants (RTEs).RTEs traffic to prostate tumors.RTEs become activated and produce...

More coverage: #cancer #ji_topread #readtheji #tumorimmunology
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Mashup Score:15

American Association of Immunologists

MicroRNAs in Macrophages: Regulators of Activation and Function - 15 hours

Mashup Score:15

Abstract. Macrophages are sentinels of the innate immune system that maintain tissue homeostasis and contribute to inflammatory responses. Their broad scope...

More coverage: #briefreview #ih_editor #innateimmunity #macrophages #micrornas #readtheji
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Mashup Score:14

ScienceDirect

ESMO Open | New emerging targets in cancer immunotherapy | ScienceDirect.com by Elsevier - 1 week

Mashup Score:14

Cancer immunotherapy has radically changed the natural history of many malignancies and is currently standard of care in several diseases. Different monoclonal antibodies blocking...

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Mashup Score:14

Trends in Immunology

‘Silent’ flagellin drives immunotolerance to commensal bacteria - 5 days

Mashup Score:14

Distinguishing between commensal and pathogenic bacteria to generate appropriate responses (tolerance vs. immunogenicity) is a key decision that the human immune system must make...

More coverage: #immunology
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