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Mashup Score: 0
Understanding the risk factors leading to severe systemic sting reactions (SSRs) is crucial for initiating venom immunotherapy (VIT) and for educating affected individuals and their families. Some of these risk factors are well established, some are no longer considered risk factors, and some remain controversial. Well-established risk factors for severe SSRs include clonal mast cell disease, high baseline serum tryptase, and advanced age. The absence of skin symptoms and the rapid onset of symptoms are indicators of severe SSRs.
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Mashup Score: 17
Nonsteroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (NSAID-ERD) is characterized by the clinical triad of chronic rhinosinusitis with nasal polyps (CRSwNP), asthma, and a hypersensitivity to medications that inhibit the cyclooxygenase (COX)-1 enzyme.1-3 The disease affects 0.6% to 2.5% of the general population and as many as 16% of patients with CRSwNP, up to 30% with severe CRSwNP, and 15% of patients with asthma. In general, patients with NSAID-ERD have more severe upper and lower respiratory tract disease compared with NSAID-tolerant patients with CRSwNP and/or asthma.
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#NSAID - #Exacerbated #Respiratory #Disease—A Century of Discovery and Innovation: NSAID-ERD is characterized by the clinical triad of #CRSwNP, #asthma, and a #hypersensitivity to medications that inhibit the #cyclooxygenase (COX)-1 enzyme. https://t.co/VvwuwwwXYV https://t.co/07bwkraoWk
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Mashup Score: 2
Penicillin allergy has emerged as an important public and individual health issue. Approaches to penicillin allergy evaluations have evolved based on clinical risk stratification. The linked articles below are important updates in the field in 2022-2023. Please also visit the Penicillin Allergy Center on the AAAAI Website for foundational literature in this
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In recognition of #NationalPenicillinAllergyDay, we are pleased to offer a link to our Drug Allergy Resource update page on this topic: https://t.co/6ne1sgioXO
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Mashup Score: 1Analyzing Racial Disparities in Pediatric Atopic Comorbidity Emergency Department Visitation using Electronic Health Records - 6 month(s) ago
Although atopic diseases and associated co-morbidities are prevalent in children, little is known about racial differences in emergency department (ED) visitation.
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Analyzing Racial Disparities in Pediatric Atopic Comorbidity Emergency Department Visitation using Electronic Health Records - The Journal of Allergy and Clinical Immunology: In Practice https://t.co/ZbzjW2BpoW . Paper written by Esteban Correa, PhD!
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Mashup Score: 15Inadequate Rhinitis Control in Real Life—What to Do? - 6 month(s) ago
The paper by Scheire et al1 in this issue of the journal makes depressing reading for those of us who have been involved in the production of rhinitis guidelines and algorithms for many years. In this real-life pharmacy study of 1514 patients, recruited in 215 Belgian pharmacies, almost 60% exhibited suboptimal rhinitis control as measured by the Rhinitis Control Assessment Test (RCAT ≤21/30).
Source: www.jaci-inpractice.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Inadequate Rhinitis Control in Real Life—What to Do? https://t.co/yiKUy450lM https://t.co/GLDAiVTsez
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Mashup Score: 4Nonallergic Rhinopathy: A Comprehensive Review of Classification, Diagnosis, and Treatment - 7 month(s) ago
Chronic nonallergic rhinitis syndromes encompass various conditions, of which vasomotor rhinitis is the most common form, representing approximately 80% of patients, also referred to as nonallergic rhinopathy (NAR), nasal hyperreactivity, neurogenic rhinitis, or idiopathic rhinitis. Expert panels have recommended replacing vasomotor rhinitis terminology because it is more descriptive of this condition that is characterized by symptoms triggered by chemical irritants and weather changes through chemosensors, mechanosensors, thermosensors, and/or osmosensors activated through different transient receptor potential calcium ion channels.
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In Current Issue! #Nonallergic #Rhinopathy: A Comprehensive Review of Classification, #Diagnosis, and #Treatment https://t.co/yqYwsUBSM9 https://t.co/ge33Lq3i3U
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Mashup Score: 14Could Corticosteroid/Antihistamine Combination Nasal Sprays Be Used as Anti-Inflammatory Reliever Therapy for Allergic Rhinitis? - 7 month(s) ago
Current guidelines advocate using regular treatment with intranasal corticosteroid/antihistamine (CS/AH) combination sprays as step-up therapy for adolescent and adult patients with moderate to severe persistent allergic rhinitis (AR) where there is suboptimal control with intranasal CS alone.1 The therapeutic rationale here is that the CS component is effective at suppressing symptoms attributable to type 2 (T2) inflammation mediated by eosinophils, whereas the AH provides additional activity on T2 symptoms mediated by IgE and mast cells.
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In Current Issue! Could #Corticosteroid/Antihistamine Combination #Nasal Sprays Be Used as #Anti-Inflammatory Reliever #Therapy for #Allergic #Rhinitis? https://t.co/X9iHaQKpAP https://t.co/LRzdmEkFFG
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Mashup Score: 19Local Allergic Rhinitis - 7 month(s) ago
Local allergic rhinitis (LAR) is defined by a clinical history suggestive of allergic rhinitis (AR), negativity of systemic IgE measurement and positive response to nasal allergen challenge (NAC). The term local respiratory allergy includes LAR, local allergic asthma (positive response in bronchial allergen challenge) and dual allergic rhinitis defined by the coexistence of AR and LAR. LAR worsens in severity and presence of comorbidities over time, and it is an independent entity from AR. Prevalence is higher in Mediterranean countries.
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In Current Issue! Local #Allergic #Rhinitis https://t.co/p4kieJNtgR https://t.co/4M7KHeNrqq
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Mashup Score: 3
Allergen immunotherapy is a recognized key therapeutic modality for the treatment of allergic respiratory disease – definitive studies have provided evidence-based data to demonstrate its effectiveness in allergic rhinitis and asthma due to the inhalation of proteinaceous allergic substances from specific seasonal pollens, dust mites, animal allergens, and certain mold spores.Over the ensuing decades, laboratory investigations, have provided objective evidence to demonstrate immunologic changes, including production of protective IgG antibody, suppression of IgE antibody, upregulation of regulatory T-cells, and an induction of a state of immune tolerance to the offending allergen(s).
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In Current Issue! #Allergen #Immunotherapy: The Evidence Supporting the #Efficacy and Safety of #Subcutaneous Immunotherapy and #Sublingual Forms of Immunotherapy for Allergic #Rhinitis/Conjunctivitis and Asthma https://t.co/GCaeeNwoly
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Mashup Score: 11Current Management of Allergic Rhinitis - 7 month(s) ago
Allergic rhinitis (AR) is the most common allergic disease worldwide and one of the most common chronic diseases in general. Allergic rhinitis is caused by inhalant allergens from outdoor and indoor environments with varying significance of different allergens in global regions. We provide options for the current management for AR including pharmacological treatments and nonpharmacological options and allergen immunotherapy (AIT). A literature review has been conducted in Medline, Pubmed, as well as the national and international study (ClinicalTrials.gov) and guideline registers and the Cochrane Library.
Source: www.jaci-inpractice.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
In Current Issue! Current Management of #Allergic #Rhinitis https://t.co/BqvjCkWq4N https://t.co/DLjlNmgpik
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JACI-IP: Risk Factors for Severe Sting Reactions and Side Effects During Venom Immunotherapy https://t.co/f3kFsJuztR