-
Mashup Score: 8Asthma COPD Overlap - 16 hour(s) ago
A 51-year-old man with a past medical history of chronic obstructive pulmonary disease (COPD) diagnosed 3 years ago (45 pack-years of cigarettes, quit 2 y ago) on 2 L/min supplemental oxygen with exertion presents to clinic for initial evaluation.
Source: www.jaci-inpractice.orgCategories: General Medicine News, Allergy-ImmunologyTweet
-
Mashup Score: 5
Vocal cord dysfunction (VCD) is a cause of acute and/or chronic respiratory symptoms. Vocal cord dysfunction, also called inducible laryngeal obstruction and paradoxical vocal fold movement, is the functional closure of vocal cords during inspiration diagnosed by direct visualization by rhinolaryngoscopy (RLG) when the patient is symptomatic, typically induced by bronchoprovocation challenges including methacholine inhalation or exercise. Vocal cord dysfunction is a common functional disorder that is often underrecognized and misdiagnosed as asthma.
Source: www.jaci-inpractice.orgCategories: General Medicine News, Allergy-ImmunologyTweet
-
Mashup Score: 6Severity of eczema at patch site during epicutaneous immunotherapy may predict subsequent response to oral immunotherapy - 3 day(s) ago
Peanut epicutaneous immunotherapy (EPIT) consisting in the daily delivery of 250 μg of peanut protein through the skin using a patch device with a condensation chamber has been shown to increase the reactivity thresholds of children with allergy while on therapy (desensitization).1-5 Its main advantage over other immunotherapy routes is that it is generally well-tolerated. Most patients will experience mild local reactions at the patch application sites (Figure 1). These include IgE-mediated urticarial lesions, which usually improve in a matter of weeks, as local skin mast cells are progressively desensitized.
Source: www.jaci-inpractice.orgCategories: General Medicine News, Allergy-ImmunologyTweet
-
Mashup Score: 0Occupational asthma in Ontario, Canada (2000-2022): a retrospective, clinic-based study evaluating sex differences - 4 day(s) ago
Clinical Implications: The findings of our clinic-based study substantiate historical sex difference trends in occupational asthma distribution and exposures and suggest increased disease severity and a trend to a longer time to diagnosis in men compared to women.
Source: www.jaci-inpractice.orgCategories: General Medicine News, PulmonologyTweet
-
Mashup Score: 0Clinical and bronchial parameters associated with the exacerbation frequency of severe preschool wheezers - 6 day(s) ago
Recurrent preschool wheezers represent approximately 10% of children under 5 years of age.1 Among them, those who report frequent exacerbations (ie, 3 or more per year), mainly due to viral and/or bacterial infections, have an increased risk of persistent asthma and poor lung function throughout life.1,2 The risk of exacerbation has been previously associated with several clinical and/or biological parameters, including those of bronchial remodeling. The latter corresponds to a poorly reversible structural abnormality of the bronchial tissue (ie, altered epithelial integrity, increased mass of mucus gland and/or bronchial smooth muscle [BSM], increased density of blood vessels, and an increased collagen deposition leading to reticular basement membrane [RBM] thickening and increased submucosal fibrosis).
Source: www.jaci-inpractice.orgCategories: General Medicine News, Allergy-ImmunologyTweet
-
Mashup Score: 10Contact Leukoderma Following Allergic Contact Dermatitis to a Smartwatch: A Consequence of Nickel Allergy - 7 day(s) ago
We present an original case of leukoderma appearing after nickel-induced allergic contact dermatitis.
Source: www.jaci-inpractice.orgCategories: General Medicine News, Allergy-ImmunologyTweet
-
Mashup Score: 5Efficacy of EDS-FLU for Chronic Rhinosinusitis: Two Randomized Controlled Trials (ReOpen1 and ReOpen2) - 7 day(s) ago
Chronic rhinosinusitis (CRS) is a prevalent inflammatory disease. No medications are Food and Drug Administration–approved for the most common form, CRS without nasal polyps (also called “chronic sinusitis”). Novel biomechanics of the exhalation delivery system deliver fluticasone (EDS-FLU; XHANCE) to sinonasal areas above the inferior turbinate, especially sinus drainage pathways not reached by standard-delivery nasal sprays.
Source: www.jaci-inpractice.orgCategories: General Medicine News, Allergy-ImmunologyTweet
-
Mashup Score: 7
Patients with primary antibody deficiency (PAD) frequently suffer from pulmonary complications, associated with severe morbidity and mortality. Hence, regular pulmonary screening by computed tomography (CT) scanning is advised. However, predictive risk factors for pulmonary morbidity are lacking.
Source: www.jaci-inpractice.orgCategories: General Medicine News, Allergy-ImmunologyTweet
-
Mashup Score: 1
Hereditary angioedema (HAE) due to C1-inhibitor (C1-INH) deficiency is characterized by unpredictable recurrent episodes of swelling affecting the skin and the mucosa tissues, including gastrointestinal tract and/or oropharyngeal-laryngeal mucosae. Long-term prophylaxis (LTP) is used to prevent attacks.
Source: www.jaci-inpractice.orgCategories: General Medicine News, Allergy-ImmunologyTweet
-
Mashup Score: 2Interaction Between Baseline Participant Factors and Treatment Effects Following Peanut Oral Immunotherapy - 8 day(s) ago
The Probiotic Peanut Oral Immunotherapy-003 multicenter randomized trial found that both probiotic peanut oral immunotherapy (PPOIT) and peanut OIT alone (OIT) were effective compared with placebo in inducing clinical remission after 18 months of treatment, and improving health-related quality of life (HRQL) at 12 months after treatment. Understanding treatment effect modifiers can optimize outcomes through precision care.
Source: www.jaci-inpractice.orgCategories: General Medicine News, Allergy-ImmunologyTweet
In Current Issue! Asthma COPD Overlap https://t.co/iOkdQE0siD https://t.co/3xqI9vJQZi