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Mashup Score: 0Conference - Vaccine Congress - 3 day(s) ago
17th Vaccine Congress
Source: www.elsevier.comCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 1Functional modulation of RAGE activation by multimeric S100B using single-domain antibodies - 10 day(s) ago
S100B is a multifunctional protein primarily found in the brain, where it plays crucial roles in cell proliferation, differentiation, and survival. It has intra- and extracellular functions and, depending on S100B levels, can exhibit both neurotrophic and neurotoxic activities, both mediated by the receptor for advanced glycation end products (RAGE). Here, we report the discovery and characterization of nanobodies (Nbs) targeting dimeric and tetrameric S100B, which are the two most abundant oligomeric functional forms of the protein, aiming to modulate S100B-mediated RAGE activation.
Source: www.jbc.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 1
Effective cancer immunotherapy relies on enhancing the host’s immune response, particularly by boosting T cell-mediated cytotoxicity against tumor cells. In this study, we identify CWF19-like cell cycle control factor 1 (CWF19L1) as a novel splicing regulator that enhances T cell-mediated cytotoxicity. CWF19L1 interacts prominently with key splicing factors within the nucleus, including components of the U5 small nuclear ribonucleoprotein and the pre-mRNA processing factor 19 (PRPF19) complex. Deficiency of CWF19L1 disrupts alternative splicing of immune-related genes, resulting in diminished expression of cytotoxic molecules.
Source: www.jbc.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 119th Vaccine Congress About - 10 day(s) ago
19th Vaccine Conference held in Kyoto, Japan, 2025.
Source: www.elsevier.comCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 0Home Page: The Journal of Precision Medicine: Health and Disease - 23 day(s) ago
Cover art provided by: Joshua P. Tulman The Journal of Precision Medicine: Health and Disease covers a wide range of topics at the intersection of physiology and personalized healthcare. It might include research on individualized treatment plans based on a person’s unique physiological characteristics, genetic makeup, and lifestyle factors. Professor Clancy is the Arline Miller Rolkin Professor in Health Innovation and serves as the Director of Precision Medicine and Data Sciences at UC Davis. She has
Source: www.jprecisionmedicine.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 119th Vaccine Congress About - 24 day(s) ago
19th Vaccine Conference held in Kyoto, Japan, 2025.
Source: www.elsevier.comCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 119th Vaccine Congress About - 1 month(s) ago
19th Vaccine Conference held in Kyoto, Japan, 2025.
Source: www.elsevier.comCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 0Palmitoleate protects against Lipopolysaccharide-induced Inflammation and Inflammasome Activity - 1 month(s) ago
Inflammation is part of natural immune defense mechanism against any form of infection or injury. However, prolonged inflammation could perturb cell homeostasis and contribute to the development of metabolic and inflammatory diseases including maternal obesity, diabetes, cardiovascular diseases, and metabolic dysfunction-associated steatotic liver diseases. Polyunsaturated fatty acids have been shown to mitigate inflammatory response by generating specialized pro-resolving lipid mediators which take part in resolution of inflammation.
Source: www.jlr.orgCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 119th Vaccine Congress About - 2 month(s) ago
19th Vaccine Conference held in Kyoto, Japan, 2025.
Source: www.elsevier.comCategories: General Medicine News, Allergy-ImmunologyTweet
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Mashup Score: 119th Vaccine Congress About - 2 month(s) ago
19th Vaccine Conference held in Kyoto, Japan, 2025.
Source: www.elsevier.comCategories: General Medicine News, Allergy-ImmunologyTweet
Award nominations now open! The 19th Vaccine Congress is offering the following awards: Schneerson Robbins Award, Jenner Award, Early Career Researcher Award, Host Country Early Career Researcher Award. Nominations close 21 February 2025. Nominate here! https://t.co/qE7vUlkAjJ https://t.co/YFNCAaOkXT