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Mashup Score: 2Metabolomics and Proteomics in Type 2 Diabetes - PubMed - 2 year(s) ago
The persistent increase in the worldwide burden of type 2 diabetes mellitus (T2D) and the accompanying rise of its complications, including cardiovascular disease, necessitates our understanding of the metabolic disturbances that cause diabetes mellitus. Metabolomics and proteomics, facilitated by r …
Source: PubMedCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 2Inosine Increases Energy Consumption in Brown Fat Cells - 2 year(s) ago
Metabolomics has uncovered that one of the metabolites released by apoptotic brown adipocytes, inosine, increases the energy consumption of brown fat cells.
Categories: Future of Medicine, Latest HeadlinesTweet-
A team of researchers applied untargeted #metabolomics to demonstrate that apoptotic brown adipocytes release a specific pattern of metabolites, enriched in purine metabolites. Learn more: https://t.co/FRFEkbECWL https://t.co/2ux6xXLmGq
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Mashup Score: 3Inosine Increases Energy Consumption in Brown Fat Cells - 2 year(s) ago
Metabolomics has uncovered that one of the metabolites released by apoptotic brown adipocytes, inosine, increases the energy consumption of brown fat cells.
Categories: Future of Medicine, Latest HeadlinesTweet-
Inosine Increases Energy Consumption in Brown Fat Cells #Metabolomics has uncovered that one of the metabolites released by apoptotic brown adipocytes, inosine, increases the energy consumption of brown fat cells. Learn more: https://t.co/FRFEkbECWL https://t.co/pyMZeSnTV5
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Mashup Score: 2Large-scale Integrated Analysis of Genetics and Metabolomic Data Reveals Potential Links Between Lipids and Colorectal Cancer Risk - 2 year(s) ago
AbstractBackground:. The etiology of colorectal cancer is not fully understood.Methods:. Using genetic variants and metabolomics data including 217 metabolites from the Framingham Heart Study (n = 1,357), we built genetic prediction models for circulating metabolites. Models with prediction R2 > 0.01 (Nmetabolite = 58) were applied to predict levels of metabolites in two large consortia with a…
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet-
#ICYMI: The etiology of #ColorectalCancer is not fully understood. Shu et al built genetic prediction models for circulating #metabolites and identified potential novel risk #biomarkers by integrating genetics and circulating #metabolomics data. https://t.co/W4dp89TBZY https://t.co/r7NpS7CJ5O
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Mashup Score: 0Large-scale Integrated Analysis of Genetics and Metabolomic Data Reveals Potential Links Between Lipids and Colorectal Cancer Risk - 2 year(s) ago
AbstractBackground:. The etiology of colorectal cancer is not fully understood.Methods:. Using genetic variants and metabolomics data including 217 metabolites from the Framingham Heart Study (n = 1,357), we built genetic prediction models for circulating metabolites. Models with prediction R2 > 0.01 (Nmetabolite = 58) were applied to predict levels of metabolites in two large consortia with a…
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet-
The etiology of #ColorectalCancer is not fully understood. Shu et al built genetic prediction models for circulating #metabolites and identified potential novel risk #biomarkers by integrating genetics and circulating #metabolomics data. https://t.co/ycpMvgOWEw https://t.co/UQjtWYOHNN
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Mashup Score: 0Metabolomic Profiling of the Effects of Dapagliflozin in Heart Failure with Reduced Ejection Fraction: DEFINE-HF - 2 year(s) ago
Background: Sodium-glucose co-transporter-2 inhibitors (SGLT2i) are foundational therapy in patients with heart failure with reduced ejection fraction (HFrEF), yet underlying mechanisms of benefit ar
Source: CirculationCategories: Cardiology News and Journals, Latest HeadlinesTweet-
#OriginalResearch Simpub #HeartFailure2022: Dapagliflozin #RCT using #metabolomics in HFrEF reveal key metabolic pathways, particularly altered ketone and fatty acid pathways with #SGLT2i @senthil_selv @svatishah @dukecardiology @MkosiborodMD #AHAJournals https://t.co/nmlPklUb1A https://t.co/UjScmSsXA2
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Mashup Score: 11Metabolomics and lipidomics in NAFLD: biomarkers and non-invasive diagnostic tests - Nature Reviews Gastroenterology & Hepatology - 3 year(s) ago
Metabolomics and lipidomics approaches are being used to identify biomarkers for nonalcoholic fatty liver disease (NAFLD). This Review discusses the application of metabolomics and lipidomics in clinical studies and in the identification of key metabolic pathway alterations in NAFLD.
Source: NatureCategories: Gastroenterology, Latest HeadlinesTweet-
#TBT REVIEW | #Metabolomics and lipidomics in #NAFLD: biomarkers and non-invasive diagnostic tests https://t.co/fYjc2A23dJ https://t.co/8fH2htvVP8
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Mashup Score: 2Comparative metabolomics with Metaboseek reveals functions of a conserved fat metabolism pathway in C. elegans - Nature Communications - 3 year(s) ago
Untargeted mass spectrometry-based metabolomics can reveal new biochemistry, but data analysis is challenging. Here, the authors develop Metaboseek, an open-source software that facilitates metabolite discovery, and apply it to characterize fatty acid alpha-oxidation in C. elegans.
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet-
Metaboseek, an open-source software from @group_schroeder, facilitates metabolite discovery and provides insight into fatty acid alpha-oxidation in C. elegans #metabolomics #lipids #fat_metabolism https://t.co/oIF8D6Ng3F https://t.co/d7ThJS8mz5
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Mashup Score: 7Cutting Edge: l-Arginine Transfer from Antigen-Presenting Cells Sustains CD4+ T Cell Viability and Proliferation - 3 year(s) ago
Metabolomics analyses suggest changes in amino acid abundance, particularly l-arginine (L-ARG), occur in patients with tuberculosis. Immune cells require L-ARG to fuel effector functions following infection. We have previously described an L-ARG synthesis pathway in immune cells; however, its role
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
#CuttingEdge from Joseph Qualls @CincyLabs @CincyChildrens | #Larginine transfer from #antigen presenting cells sustains CD4+ #Tcell viability and proliferation https://t.co/WZFMFVs4R1 #ReadTheJI #immunology #DendriticCells #Metabolomics #Tuberculosis https://t.co/f6zfzruaMh
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Mashup Score: 11H-NMR metabolomics-based surrogates to impute common clinical risk factors and endpoints - 3 year(s) ago
To conclude, we provide 1H-NMR metabolomics-based models to impute clinical variables routinely assessed in epidemiological studies and illustrate their merit in scenarios when phenotypic variables are partially incomplete or totally unobserved.
Source: EBioMedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
3rd highlight of our Jan issue, @DanieleBizzarr2 @erikvandenakker from @LUMC_Leiden propose to leverage #metabolomics to impute missing data in clinical variables routinely assessed in large epidemiological and clinical studies. Read https://t.co/Enm9hm9hgJ https://t.co/nDqe28Cjvu
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RT @MetwareGlobal: A paper in @CircRes proves #Metabolomics and #Proteomics in T2D(Type 2 Diabetes). 📖https://t.co/1WIar7xu3b (IF=17.367)…