• Mashup Score: 1
    Shortness of Breath and Near Syncope During Exertion in a Child: When–Patients–Worry Syndrome - 1 year(s) ago

    ECG CHALLENGEA previously healthy 14-year-old male patient reported shortness of breath and near syncope during a basketball game. His initial evaluation by a pulmonologist included an exercise pulmonary function test that was reported as normal. The patient presented for cardiac evaluation for persistent symptoms. On general physical examination, his vital signs and clinical cardiac examination…

    Source: Circulation
    Categories: Cardiology News and Journals, Latest Headlines
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    • Profile photo of CircAHA
      CircAHA

      #ECGchallenge Teenager presents with near syncope during a basketball game, found to have a normal echo and physical exam. Holter below. # pre excitation #AHAJournals https://t.co/xnjs80DDUv https://t.co/TARTor5vUS

  • Mashup Score: 3
    What Is the Future of Factor XI Inhibitors? - 1 year(s) ago

    Jeffrey I. Weitz Correspondence to: Jeffrey Weitz, Thrombosis and Atherosclerosis Research Institute, 237 Barton Street East, Hamilton, Ontario, Canada L8L 2X2. Email E-mail Address: [email protected] https://orcid.org/0000-0002-1092-7550 Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada (J.I.W., J.W.E.). Departments of Medicine (J.I.W., J.W.E.), McMaster University,…

    Source: Circulation
    Categories: Cardiology News and Journals, Latest Headlines
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    • Profile photo of CircAHA
      CircAHA

      #Perspective What is the Future of Factor XI inhibitors?Factor XI inhibitor therapy - unmet needs in anticoagulation therapy - more important for thrombosis than for hemostasis - perspective on the opportunities and challenges for this new class of anti... https://t.co/qAIoseiSvj https://t.co/SS3umrO4zc

  • Mashup Score: 0
    Sudden Cardiac Death in the Athlete - 1 year(s) ago

    IntroductionSudden cardiac death (SCD) in a young athlete commonly brings to the forefront the many gaps in knowledge regarding how to predict and prevent these rare tragic events.1–3 Although the number of athletic sudden deaths is relatively small, with ≈100 to 150 competitive deaths during sports in the United States annually, they represent an important and emotionally charged public health…

    Source: Circulation
    Categories: Latest Headlines, Pediatrics
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  • Mashup Score: 1
    2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials - 1 year(s) ago

    This publication describes uniform definitions for cardiovascular and stroke outcomes developed by the Standardized Data Collection for Cardiovascular Trials Initiative and the US Food and Drug Admin

    Source: Circulation
    Categories: Cardiologists, Latest Headlines
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    • Profile photo of mvaduganathan
      mvaduganathan

      @hvanspall @cardskrish @djc795 @PFinanceiros @BartoszHudzik @bmj_latest @DrMarthaGulati @mmamas1973 @gbiondizoccai @HeartOTXHeartMD @drjohnm @DLBHATTMD @kaulcsmc @Hragy @gina_lundberg @ErinMichos @iamritu @MKIttlesonMD @AndrewJSauer @CMichaelGibson Agree, @hvanspall. And differentiating “cardiac” (like MI & HF) from “vascular” (like stroke) doesn’t seem consistent with accepted standard regulatory definitions of CV endpoints. Typically all analyzed together as “CV mortality” as was done in #FOURIER https://t.co/ITLcMo3Aa1

  • Mashup Score: 1
    Emulating Randomized Clinical Trials With Nonrandomized Real-World Evidence Studies - 1 year(s) ago

    Background: Regulators are evaluating the use of noninterventional real-world evidence (RWE) studies to assess the effectiveness of medical products. The RCT DUPLICATE initiative (Randomized, Control

    Source: Circulation
    Categories: Expert Picks, Latest Headlines
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    • Profile photo of VPrasadMDMPH
      VPrasadMDMPH

      I am not sure 1 off studies prove much 99% of oncs think Folfirinox better (but adjuvant Folfirinox changes things a bit) Validation reqs. knowing how often to target trials replicate A SET OF RCTs on same q Sebastian finds poor concordance @drtoddlee https://t.co/Upzwq2V9fs https://t.co/OtuHaepNiy

  • Mashup Score: 1
    The Value of Measuring Lipoprotein(a) in Children - 1 year(s) ago

    FootnotesThe opinions expressed in this article are not necessarily those of the editors or of the American Heart Association.For Sources of Funding and Disclosures, see page 34.Circulation is available at www.ahajournals.org/journal/circCorrespondence to: Michael Khoury, MD, Pediatric Cardiology, Department of Pediatrics, Stollery Children’s Hospital, 8440-112th St NW, Edmonton, AB, Canada T6G…

    Source: Circulation
    Categories: Cardiologists, Latest Headlines
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      ShoaClarke

      We perform lipid screening in children to identify those at high risk of premature heart disease. We should be measuring Lp(a) too! Here, @makhoury and I describe why: https://t.co/dB8NT75Ppv

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