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Mashup Score: 2
Macroautophagy involves the delivery of various macromolecules and organelles to lysosomes for degradation. In this Review, Christopher Griffey and Ai Yamamoto provide an overview of this intracellular process and consider its modulation under physiological conditions and in brain disorders.
Source: NatureCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 4Human Cathelicidin Peptide LL-37 Induces Cell Death in Autophagy-Dysfunctional Endothelial Cells - 2 year(s) ago
Human cathelicidin LL-37 is an antimicrobial peptide that has a broad spectrum of antimicrobial activities but also acts on host cells to exert immunomodulatory functions. It has been suggested that the increase of LL-37 in atherosclerotic aortas and the dysregulated autophagy of endothelial cells
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
#AuthorChoice: Human #cathelicidin peptide LL-37 induces #celldeath in the #autophagy-dysfunctional #endothelialcells from Isao Nagaoka @juntendo1838 #FreetoRead #ReadTheJI #immunology https://t.co/9YuBNtCXLw https://t.co/VnPusDK79y
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Mashup Score: 1eIF3k inhibits NF-κB signaling by targeting MyD88 for ATG5-mediated autophagic degradation in teleost fish - 2 year(s) ago
Optimal activation of NF-κB signaling is crucial for the initiation of inflammatory responses and eliminating invading bacteria. Bacteria have likewise evolved the ability to evade immunity; however, mechanisms by which bacteria dysregulate host NF-κB signaling are unclear. In this study, we identify eukaryotic translation initiation factor eIF3k, a nonessential member of the eIF3 translation…
Source: Journal of Biological ChemistryCategories: Allergy-Immunology, Latest HeadlinesTweet-
Chen et al. conclude that Vibrio harveyi can manipulate a host's #autophagy process to evade immunity in fish and also provide a new perspective on mammalian resistance to bacterial invasion — Shanghai Ocean University #elF3k https://t.co/8cjJCYLrvA
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Mashup Score: 9Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atherosclerosis - 2 year(s) ago
Rationale: Atherosclerosis is characterized by an accumulation of foam cells within the arterial wall, resulting from excess cholesterol uptake and buildup of cytosolic lipid droplets (LDs). Autophag
Source: Circulation ResearchCategories: Cardiology News and Journals, Latest HeadlinesTweet-
Robichaud et al found in #atherosclerosis #VSM derived-foam cells fail to initiate #autophagy. Learn how activation of autophagy in VSM alters atherosclerosis progression at https://t.co/dJMkkfJ4mE @adilrasheed88 @SabbRob @MireilleOuimet @kateyrayner @LaraGharibeh https://t.co/8aGpR2yBTK
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Mashup Score: 3Protection of Quiescence and Longevity of IgG Memory B Cells by Mitochondrial Autophagy - 2 year(s) ago
This article is featured in Top Reads , p.[][1] [1]: /lookup/volpage/208/999
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
#JI_TopRead from Jin Wang @MethodistHosp | #mitochondrial #autophagy is crucial for metabolic reprogramming protect #memoryBcell survival | #ReadTheJI #immunology #quiescence #immunememory https://t.co/dDUVszp7KO https://t.co/kt9ZxNyzsw
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Mashup Score: 0
Abstract Background Autophagy is a cellular process that degrades a cell’s own cytoplasmic components for energy provision and to maintain a proper intracellular environment. Left ventricular rever…
Categories: Cardiologists, Latest HeadlinesTweet-
#Autophagy adaptively responds to #HF and is associated with prognosis in patients with DCM Increases in autophagic vacuole number and cathepsin D expression of endomyocardial biopsy specimens predicts LV remodeling and favorable outcomes https://t.co/FaQRxRNmn4 @JACCJournals https://t.co/eNWDR0QGVA
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Mashup Score: 0Perinatal versus adult loss of ULK1 and ULK2 distinctly influences cardiac autophagy and function - 2 year(s) ago
(2022). Perinatal versus adult loss of ULK1 and ULK2 distinctly influences cardiac autophagy and function. Autophagy. Ahead of Print.
Source: Taylor & FrancisCategories: Endocrinology, Latest HeadlinesTweet-
Pleased to share our most recent publication dissecting developmental role of ULK kinase on #autophagy in the heart. @AutophagyPapers Great Job @mpharris9! https://t.co/Gz0OgbEzBl
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Mashup Score: 0Ulk1-dependent alternative mitophagy plays a protective role during pressure overload in the heart - 2 year(s) ago
AbstractAims. Well-controlled mitochondrial homeostasis, including a mitochondria-specific form of autophagy (hereafter referred to as mitophagy), is essential
Source: OUP AcademicCategories: Cardiology News and Journals, Latest HeadlinesTweet-
A path less taken for #mitophagy Ulk1-mediated alternative mitophagy is critical to maintain #mitochondria quality control & #cardiac function in #HeartFailure https://t.co/Yod0mKB8xd @CVR_TomaszGuzik @DrMikeDrozd @glenpyle #HF #autophagy #CardiovascularResearch https://t.co/SE1UmTGEmF
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Mashup Score: 0Rivaroxaban, a Direct Oral Factor Xa Inhibitor, Attenuates Atherosclerosis by Alleviating Factor Xa–PAR2-Mediated Autophagy Suppression: - 2 year(s) ago
Visual Abstract
Categories: Cardiologists, Latest HeadlinesTweet-
Is #DOAC efficient on #atherosclerosis by inhibiting #autophagy ? More informations https://t.co/b9MRZs0p8W
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Mashup Score: 5
The cellular consequences of dysfunctional autophagy contribute to numerous diseases. In this Review, Kitada and Koya consider the relationship between impaired autophagy and age-related metabolic derangements, including insulin resistance, type 2 diabetes mellitus and sarcopenic obesity, and discuss candidate autophagy-based therapies.
Source: NatureCategories: Endocrinology, Latest HeadlinesTweet-
Munehiro Kitada & Daisuke Koya review the role of #autophagy in the pathogenesis of #metabolic diseases associated with or occurring in the context of ageing (£) https://t.co/3nBufKQMmW https://t.co/H4io9GbNGi
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Macroautophagy in CNS health and disease – a new Review by Christopher J. Griffey (@c_griffey) and Ai Yamamoto #autophagy https://t.co/fYDKjWZ5uj https://t.co/7pSvECrzTF