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Mashup Score: 1The National Kidney Foundation’s 2024 Spring Clinical Meetings - 3 hour(s) ago
(May 14, New York, NY) – During a late-breaking abstract presentation at the annual 2024 NKF Spring Clinical Meetings (SCM) tomorrow Dr. Dana Rizk, from the University of Alabama at Birmingham (UAB)
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Mashup Score: 0ASN Efforts to Address Challenges Highlighted in Recent... : Journal of the American Society of Nephrology - 4 hour(s) ago
An abstract is unavailable. This article is available as a PDF only.
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Mashup Score: 0Association of Preterm Birth with Adverse Glomerular... : Clinical Journal of the American Society of Nephrology - 4 hour(s) ago
glomerular disease are unknown. Methods: We performed a cross-sectional and longitudinal analysis of participants in the Cure Glomerulonephropathy (CureGN) cohort. Preterm (<37 weeks’ gestation) was compared to term (≥37 weeks’ gestation). A survival analysis and adjusted Cox proportional hazards model were used to examine a composite outcome of 40% decline in estimated glomerular filtration rate (eGFR) or progression to kidney failure. An adjusted logistic regression model was used to examine remission of proteinuria. Results: There were 2,205 term and 235 preterm participants. APOL1 risk alleles were more common in those born preterm. More pediatric than adult participants in CureGN were born preterm: 12.8% vs. 7.69% (P<0.001). Adults born preterm as compared to term had a higher prevalence of Focal Segmental Glomerulosclerosis (FSGS) (35% vs. 25%, P=0.01) and APOL1 high-risk genotype (9.4% vs 4.2%, P=0.01). Participants born preterm had a shorter time interval to a 40% eGFR decline/
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Mashup Score: 7
Submit your abstract for Kidney Week 2024.
Source: www.asn-online.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 0Development and Validation of the Rating of CKD Knowledge Among Older Adults (Know-CKD) with Kidney Failure - 5 hour(s) ago
Few older adults with kidney failure engage in shared decision-making (SDM) for kidney replacement therapy. Absence of instruments assessing SDM-relevant knowledge domains may contribute to this. We assessed the reliability and validity of a new instrument, the Rating of CKD Knowledge Older Adults (Know-CKD).
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Mashup Score: 19Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the kidney - 6 hour(s) ago
Nature Reviews Nephrology – Ferroptosis is an iron-dependent mechanism of regulated necrosis that is driven by the robust oxidation of polyunsaturated fatty acid-containing phospholipids. This…
Source: www.nature.comCategories: General Medicine News, NephrologyTweet
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Mashup Score: 2Bolstering Clinician Mental Health and Well-Being - 7 hour(s) ago
Serving the Underserved The following article is the final part of a five-issue series focused on caring for patients in underserved populations. Inspired by several sessions at Kidney Week 2023, this series has featured unique patient and physician perspectives, explained legal protections and limitations, and has sought to identify opportunities to improve kidney care for these communities. In this final article, we focus on the mental and emotional well-being of clinicians—pivotal in effectively caring for patients with kidney diseases and their mental health.
Source: www.kidneynews.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 3Protected Time for Program Administration among Nephrology... : Clinical Journal of the American Society of Nephrology - 7 hour(s) ago
n anonymous, online survey of all US adult nephrology program directors (March 2023), who forwarded core faculty/associate program director (APD) surveys. The questions included protected time in 2022–2023 and 2021–2022, whether it was sufficient, estimated time needed, and two validated single-item burnout measures (emotional exhaustion and depersonalization). The analysis was descriptive. Results Program directors: Their response was 62% (92/149), with geographic distribution/approved fellow positions similar to those nationally. Overall, protected time slightly increased from 2021 to 2022, largely in >6-fellow programs, but 42% (13/31) of these were still not meeting minimum requirements. Only 37% (30/81) agreed that they had sufficient protected time. Those with ≤6 fellows estimated needing 11±4 h/wk (15±4 h/wk with >6 fellows). Twenty-five percent (20/81) reported high levels of emotional exhaustion. Core faculty: 57 of 149 program directors (38%) forwarded the link to 454 faculty
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Mashup Score: 0Membership - Renal Physicians Association - 7 hour(s) ago
The RPA offers membership categories for every stage of your professional career with corresponding annual dues. In exchange for membership dues, you will benefit from a wide range of resources to enhance your professional growth and keep you connected. Join our community! Employers and job seeking renal professionals take next steps in their professional journey to find the opportunity that’s right for them. This is how RPA can help you! Check out our 10 powerful features. Recognizing, connecting and
Source: www.renalmd.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 13Combination Treatment with Verinurad and Allopurinol in... : Journal of the American Society of Nephrology - 7 hour(s) ago
t compared with allopurinol alone or placebo.Verinurad/allopurinol combination dose-dependently reduced serum urate concentrations compared with placebo. Background Hyperuricemia is associated with elevated risks of cardiovascular and chronic kidney disease (CKD). Since inhibition of urate transporter 1 has been suggested to be potentially nephroprotective, we performed a phase 2b study to assess albuminuria-lowering effects of the urate transporter 1 inhibitor verinurad combined with the xanthine oxidase inhibitor allopurinol in patients with CKD and hyperuricemia. Methods In this randomized placebo and active controlled trial, we enrolled participants with serum urate concentrations ≥6.0 mg/dl, eGFR ≥25 ml/min per 1.73 m2, and a urinary albumin-creatinine ratio (UACR) 30–5000 mg/g to one of five treatment arms: placebo, placebo+allopurinol 300 mg/day, verinurad 3 mg+allopurinol 300 mg/day, verinurad 7.5 mg+allopurinol 300 mg/day, or verinurad 12 mg+allopurinol 300 mg/day in a 1:1:1:1
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During a late-breaking abstract presentation at the 2024 NKF Spring Clinical Meetings, Dr. Dana Rizk will present data on the impact and safety of Fabhalta (iptacopan) in the treatment of patients with IgA nephropathy. #NKFClinicals https://t.co/a3iqoyD2Rq