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Mashup Score: 29Peritoneal Dialysis Technique Survival: A Cohort Study - 22 hour(s) ago
Reasons for transfer from peritoneal dialysis (PD) to hemodialysis (HD) remain incompletely understood. Among incident and prevalent patients receiving PD, we evaluated the association between prior treatment with HD and PD technique survival.
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Mashup Score: 45Precision Medicine in Nephrology: An Integrative Framework of Multidimensional Data in the Kidney Precision Medicine Project - 1 day(s) ago
Chronic kidney disease (CKD) and acute kidney injury (AKI) are heterogeneous syndromes defined clinically by serial measures of kidney function. Each condition possesses strong histopathologic associations, including glomerular obsolescence or acute tubular necrosis, respectively. Despite such characterization, there remains wide variation in patient outcomes and treatment responses. Precision medicine efforts, as exemplified by the Kidney Precision Medicine Project (KPMP), have begun to establish evolving, spatially anchored, cellular and molecular atlases of the cell types, states, and niches of the kidney in health and disease.
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Mashup Score: 9Association of Blood Mitochondrial DNA Copy Number With Risk of Acute Kidney Injury After Cardiac Surgery - 2 day(s) ago
Acute kidney injury (AKI) is a common complication of cardiac surgery and its occurrence is associated with increased risk of all-cause mortality, adverse cardiovascular outcomes, and chronic kidney disease (CKD).1 Mitochondria are essential for healthy function of the kidneys due to their roles in oxidative phosphorylation, reactive oxygen species generation, and programmed cell death.2 Experimental evidence suggests that mitochondrial dysfunction is a key contributor to the pathophysiology of acute kidney injury (AKI) and that replenishment of mitochondrial stores is necessary for recovery from AKI,3-5 but limited data exist in humans.
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Mashup Score: 12Tunneled Hemodialysis Catheter Tip Design and Risk of Catheter Dysfunction: An Australian Nationwide Cohort Study - 2 day(s) ago
Hemodialysis catheter dysfunction is an important problem for patients with kidney failure. The optimal design of the tunneled catheter tip is unknown. This study evaluated the association of catheter tip design with the duration of catheter function.
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Mashup Score: 23
Studies have shown that generally healthy individuals who consume diets rich in plant foods have a lower risk of incident chronic kidney disease (CKD) and cardiovascular disease. This study investigated the prospective associations of plant-based diets with the risk of CKD progression and all-cause mortality in patients with CKD.
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Adherence to Plant-Based Diets and Risk of CKD Progression and All-Cause Mortality: Findings From the @CRICStudy https://t.co/QgpXMOJzze (FREE temporarily) @hyunjukim25 @anacaricardo @ThidaChanTan @sankarnava @chanders4 @JHUWelchCenter @JohnsHopkinsEPI https://t.co/SxR3bRhUP2 https://t.co/OZaug4GGMu
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Mashup Score: 1
Improving the quality of care delivered to patients receiving maintenance dialysis and reducing their cost of care are central focuses for patients, providers, and payers. While numerous quality measures are employed throughout the dialysis and kidney care spaces, the most important for patients and clinicians are hospitalizations and survival. Hospitalizations also portend significant financial burden. In 2021, one-third of Medicare spending for beneficiaries with end-stage kidney disease was for inpatient care.
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Mashup Score: 108
Toxic nephropathies are a clinically common group of disorders characterized by toxin-induced renal injury that can affect the glomerulus, vasculature, or tubulointerstitium. Various endogenous (eg, myoglobin, hemoglobin, monoclonal light chains, and lysozymes) and exogenous toxins (eg, therapeutic drugs, herbal medications, heavy metals, radiocontrast, intoxicants, and environmental exposures) have been implicated. The kidney’s primary role of metabolism and excretion of substances via glomerular filtration and tubular secretion increases its susceptibility to their adverse effects.
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Mashup Score: 16
AJKD invites applications for its Editorial Internship Program, which will provide editorial experience to early career researchers interested in education, teaching, or medical editing/writing. AJ…
Source: ajkdblog.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 41Kidney Energetics and Cyst Burden in Autosomal Dominant Polycystic Kidney Disease: A Pilot Study - 4 day(s) ago
In this pilot study, we hypothesized that autosomal dominant polycystic kidney disease (ADPKD) is characterized by impaired kidney oxidative metabolism that associates with kidney size and cyst burden.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet-
Kidney Energetics and Cyst Burden in Autosomal Dominant Polycystic Kidney Disease https://t.co/MpkJxCynhH @PBjornstadMD @KristenlNowak @CortneySteele @michelchonchol @KristenJNadeau @C_Birznieks @KatharinaHopp85 @AdrianaVGregory @DenisPBlondin @CU_Kidney @CUMedicalSchool #ADPKD https://t.co/pHoG1GeJFZ
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Mashup Score: 71Erythrocytosis and CKD - 4 day(s) ago
Erythrocytosis or polycythemia is defined as an increase in red blood cell concentration above the age- and sex-specific normal levels. Unlike anemia that is very common in chronic kidney disease (CKD) patients, erythrocytosis is less frequent but requires specific understanding by healthcare professionals in order to provide the best care. Erythrocytosis, especially when undiagnosed and untreated, can lead to serious thrombotic events and higher mortality. Classical causes of erythrocytosis associated with CKD include cystic kidney diseases, kidney or other erythropoietin-secreting neoplasms, high-altitude renal syndrome, overdosage of erythropoietin-stimulating agents, androgen therapy, heavy smoking, chronic lung disease, obstructive sleep apnea, IgA nephropathy, post-kidney transplant erythrocytosis, renal artery stenosis and congenital etiologies.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet-
This review focusses on the pathogenesis, renal manifestations and management of PV, the pathophysiology of erythrocytosis induced by SGLT2 inhibitors and the relevance of timely JAK2 mutation screening: https://t.co/KZkpbFDMSV (FREE) @MabelAoun @MichelJado1204 @hjanders_hans https://t.co/64tQV1R5By
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Peritoneal Dialysis Technique Survival: A Cohort Study https://t.co/dabN1msZ4U @CarolineMHsu @DanTheKidneyMan @ChristosArgyrop @TuftsMCKidney @TuftsMedicalCtr #VisualAbstract https://t.co/E2aM1q18cf