• Mashup Score: 2
    Newts unleashed: Limb muscle regeneration needs metamorphosis and body growth - 2 year(s) ago

    Researchers from the University of Tsukuba have found that muscle fibers in Japanese Fire-bellied Newts have an intrinsic ability to dedifferentiate, or reprogram, and contribute to limb regeneration. The results indicate that changes in the niche (the environment outside the cell) during metamorphosis and body growth are needed to unleash this ability. This study provides a key basis for future…

    Source: EurekAlert!
    Categories: General Medicine News, Latest Headlines
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      EurekAlert

      The hidden powers of #newts: Muscle cells reprogram during limb #regeneration thanks to metamorphosis and body growth @UNIV_TSUKUBA_EN #lifesciences #amphibians #cellbiology https://t.co/O9gAfYQkvk

  • Mashup Score: 0
    KMT2D-NOTCH Mediates Coronary Abnormalities in Hypoplastic Left Heart Syndrome - 2 year(s) ago

    Zhiyun YuZhiyun Yu https://orcid.org/0000-0001-6568-9978 Perinatal Institute, Division of Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH (Z.Y., Z.L., V.P.-G., M.G., Y.M., M.G.). Center for Stem Cell and Organoid Medicine, CuSTOM, Division of Developmental Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH (Z.Y., Z.L., V.P.-G., Y.M., M.G.)….

    Source: Circulation Research
    Categories: Cardiology News and Journals, Latest Headlines
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      CircRes

      Yu et al revealed defects in #KMT2D-#NOTCH signaling contributed to impaired growth & remodeling of coronary #AECs in #HLHS which may lead to a potential therapeutic target for heart #regeneration and repair. https://t.co/9lmRU1KuJ7 @MingxiaGu @seema_mital @Wanleon_wn https://t.co/H5StANsQbg

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    mTOR activity is essential for retinal pigment epithelium regeneration in zebrafish - 2 year(s) ago

    Author summary Age-related macular degeneration (AMD) is a leading cause of blindness world-wide, with incidences predicted to rise substantially over the next few decades. Cells of the retinal pigment epithelium (RPE) are affected in AMD and there are currently no effective therapies that slow RPE cell death or restore lost RPE cells in advanced-stage AMD. An exciting potential approach to treat…

    Source: journals.plos.org
    Categories: Genetics, Latest Headlines
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      PLOSGenetics

      New #vision research: Lu et al show that mTOR activity is essential for regeneration of the retinal pigment epithelium in #zebrafish Their work could one day lead to treatments for #MacularDegeneration #genetics #regeneration #retina https://t.co/J6JKeL1LuV

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    Dendrite regeneration in C. elegans is controlled by the RAC GTPase CED-10 and the RhoGEF TIAM-1 - 2 year(s) ago

    Author summary The knowledge of the repair of injured neural circuits comes from the study of the regeneration of injured axons. The information receiving neurites, namely dendrites, are also vulnerable to physical insult during stroke and trauma. However, little knowledge is available on the mechanism of dendrite regeneration since the study of Cajal. In order to get insight into this process,…

    Source: journals.plos.org
    Categories: Genetics, Latest Headlines
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      PLOSGenetics

      New research on dendrite #regeneration: Brar et al @GhoshRoyLab @DBT_NBRC study the regeneration of PVD #neurons in C. elegans & find the GTPase CED-10 is critical for dendrite fusion 🔎: https://t.co/VU1XbaRSFd 📷 Harjot Kaur Brar #Genetics #neuroscience #Celegans https://t.co/9DZ0321NXl

  • Mashup Score: 1
    Adult T-cells impair neonatal cardiac regeneration - 2 year(s) ago

    AbstractAims. Newborn mice and humans display transient cardiac regenerative potential that rapidly declines postnatally. Patients who survive a myocardial infa

    Source: OUP Academic
    Categories: Cardiologists, Latest Headlines
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      ehj_ed

      T-cell involvement in the neonatal cardiac ‘regenerative-to-scarring’ transition: read more about cardiac regeneration following myocardial infarction! https://t.co/u3eLuIiYCc #cardiac #regeneration #myocardial #infarction @escardio @ESC_Journals #cardiotwitter #EHJ https://t.co/SDvDNo22XY

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