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    Genetics - PLOS - 2 year(s) ago

    Collaborating with researchers from every sub-field, career stage, and demographic to explore, share, and connect the varied complexities of genes and their impact on life in all organisms.

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    Genetics - PLOS - 2 year(s) ago

    Collaborating with researchers from every sub-field, career stage, and demographic to explore, share, and connect the varied complexities of genes and their impact on life in all organisms.

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    • Have you explored PLOS Genetics articles lately? We invite you to explore some of our most read articles from the past several years: https://t.co/xSQRxv1wH9 https://t.co/TVPKBh2vv5

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    Author summary Some pest populations can be successfully controlled by the inundative release of sterile males, but this approach is not practicable when the target population is large or the species difficult to rear. Computer modelling has previously demonstrated that releasing males with a genomic editor on their Y chromosome that kills or sterilises female descendants could be much more…

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    • In a recent study, René Geci, Katie Willis and Austin Burt show how Y-linked editors can be used in more efficient gene drive designs that may form the basis of a highly flexible set of genetic strategies for pest population control. https://t.co/yuaeNVAoDO

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    Author summary Quiescence is a very common and important state for the cells of many organisms, where cell functions ‘pause’ but can resume when the right conditions are met. Most microbes exist in a quiescent state and will start growing and dividing again in the presence of nutrients or other cues. In mammals, a quiescent state is used to maintain stem cell populations and cancer cells often…

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    • In a recent article, Thomas Bailey and colleagues outline findings that demonstrate the role of the protein Tup1 in transcriptional reprogramming in response to environmental cues leading to the quiescent state. https://t.co/7BgHW9JC8o

  • Mashup Score: 1

    Author summary Some pest populations can be successfully controlled by the inundative release of sterile males, but this approach is not practicable when the target population is large or the species difficult to rear. Computer modelling has previously demonstrated that releasing males with a genomic editor on their Y chromosome that kills or sterilises female descendants could be much more…

    Tweet Tweets with this article
    • In a recent study, René Geci, Katie Willis and Austin Burt show how Y-linked editors can be used in more efficient gene drive designs that may form the basis of a highly flexible set of genetic strategies for pest population control. https://t.co/yuaeNVAoDO

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    Author summary After mating, Drosophila females undergoes striking behavioral changes, especially in their activity patterns. Despite some of the circuits that deliver mating signals to the female brain are known, the connection with the circadian network has not been explored in detail. Here, we show that mating changes the onset of daily activity, masking a central function of the clock. This…

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    • Mating disrupts morning anticipation in Drosophila melanogaster females https://t.co/HepZok52sH https://t.co/l93F67yVdU

  • Mashup Score: 1

    Author summary Quiescence is a very common and important state for the cells of many organisms, where cell functions ‘pause’ but can resume when the right conditions are met. Most microbes exist in a quiescent state and will start growing and dividing again in the presence of nutrients or other cues. In mammals, a quiescent state is used to maintain stem cell populations and cancer cells often…

    Tweet Tweets with this article
    • In a recent article, Thomas Bailey and colleagues outline findings that demonstrate the role of the protein Tup1 in transcriptional reprogramming in response to environmental cues leading to the quiescent state. https://t.co/7BgHW9JC8o

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    Author summary Genetic data from families can be used to evaluate social effects of parents on their offspring. For example, non-transmitted parental genetic variants have been shown to associate with offspring educational attainment indicative of parental effects. Siblings may also influence one another but available data has limited our understanding of sibling effects. Associations between…

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    • Howe et al find evidence suggesting that older siblings influence the educational attainment of younger siblings @laurencejmshowe @nm_davies @BrisPopHealth https://t.co/Cboc0x8fRO