-
Mashup Score: 0Differential gene expression analysis identified determinants of cell fate plasticity during radiation-induced regeneration in Drosophila - 2 year(s) ago
Author summary Ionizing radiation (IR) is used to treat half of all cancer patients because of its ability to kill cells but treatment failures are common because tumors grow back (regenerate). Here, we asked which changes in the properties of cells facilitate regeneration in Drosophila (fruit flies) after exposure to radiation. We identified six genes whose products increase or decrease the…
Source: journals.plos.orgCategories: Genetics, Latest HeadlinesTweet
-
Mashup Score: 0Differential gene expression analysis identified determinants of cell fate plasticity during radiation-induced regeneration in Drosophila - 2 year(s) ago
Author summary Ionizing radiation (IR) is used to treat half of all cancer patients because of its ability to kill cells but treatment failures are common because tumors grow back (regenerate). Here, we asked which changes in the properties of cells facilitate regeneration in Drosophila (fruit flies) after exposure to radiation. We identified six genes whose products increase or decrease the…
Source: journals.plos.orgCategories: Genetics, Latest HeadlinesTweet-
What cell properties aid cell #regeneration after exposure to ionizing radiation (ex. #CancerTreatment) Ledru et al identify 6 genes in #Drosophila that ⬆️ or ⬇️ the regenerative potential of cells 🔎: https://t.co/OIM9npRxO4 #genetics #radiation https://t.co/5syB9aMjjU
-
-
Mashup Score: 9
Author summary Since most neurons are not replaced over an organism’s lifetime, neurons must regenerate damaged axons in order to restore function after injury. Despite the importance of regeneration to organism function, behavior and survival, regeneration is often actively inhibited in mature animals. Our results show that distant tissues can block regeneration. We show for the first time that…
Source: journals.plos.orgCategories: Genetics, Latest HeadlinesTweet-
The gut regulates the nervous system? Lin-Moore et al @AlexLin_Moore @MarcHammarlund show in #Celegans, the intestine secretes neuropeptides that block motor neuron axon regeneration 🔎: https://t.co/vlhVgQyfY2 @YaleGenetics #neurons #regeneration #genetics #nervoussystem https://t.co/ONurwJhu45
-
-
Mashup Score: 8Central nervous system regeneration - 2 year(s) ago
Successful clinical regeneration of central nervous system neurons following injury is still out of reach, but recent mechanistic discoveries illuminate a roadmap to achieve this long-held dream of neuroscience research.
Source: CellCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Read the new Review, Central #nervous system #regeneration, from Supraja Varadarajan, John Hunyara, Natalie Hamilton, Alex Kolodkin, Andrew Huberman @Stanford @HopkinsMedicine https://t.co/nrKRvk2Qp4 https://t.co/Jdo19xDkDb
-
-
Mashup Score: 0Histone deacetylase 1 controls cardiomyocyte proliferation during embryonic heart development and cardiac regeneration in zebrafish - 2 year(s) ago
Author summary Heart disease is one of the most common causes of death in all developed countries. While zebrafish cardiomyocytes are able to proliferate throughout adulthood, mammalian cardiomyocytes lose this ability during early development, and therefore are not capable to replace and renew cardiomyocytes after injury. The underlying mechanisms of cardiomyocyte proliferation are still not…
Source: journals.plos.orgCategories: Genetics, Latest HeadlinesTweet-
How do #zebrafish retain the ability to grow new cardiomyocytes, and repair heart damage, as adults? Bühler et al @just_steffen identify a role of the gene Hdac1 in embryonic heart growth and adult #regeneration 🔎: https://t.co/8BI1kiWFXk #HeartDisease #Genetics https://t.co/AzQxxg755c
-
-
Mashup Score: 1Spontaneous Bone Regeneration of Distal Half Ulnar Segment After Open Fracture of Forearm in a Pediatric Case - 2 year(s) ago
Loss of the radius with open fractures of the forearm is rarely reported in pediatric cases and to the authors’ knowledge, cases of segmental loss of the distal half of the ulna have not been previously reported. A 6-year-old girl was admitted with a Gustilo-Anderson type IIIB open forearm fracture and loss of the distal half of the ulna after a motor vehicle accident. Serial debridement was…
Source: Journal of Hand SurgeryCategories: Latest Headlines, RheumatologyTweet-
Spontaneous #BoneRegeneration of #DistalHalfUlnar Segment After #OpenFracture of #Forearm in a #Pediatric Case @HaberVANYYU #fracture #regeneration #BoneLoss #HandSurgery #OrthoTwitter #MedTwitter #CaseReport https://t.co/wJZgfNrTTz
-
-
Mashup Score: 2Regeneration Research Finds a Rich Model in a Marine Worm - 3 year(s) ago
Scientists at Harvard University have generated a toolkit to enable in-depth study of cellular and molecular mechanisms in a species of marine worms called Hofstenia miamia (also called the three-banded panther worm) that are capable of extensive whole-body regeneration. The new transgenically-enabled model system will facilitate understanding of a major animal lineage that is largely unstudied….
Categories: Future of Medicine, Latest HeadlinesTweet-
Scientists at @Harvard have generated a toolkit to enable in-depth study of cellular and molecular mechanisms in a species of marine worms called Hofstenia miamia that are capable of extensive whole-body #regeneration. Learn more: https://t.co/KFBwQthvfQ https://t.co/dh5wHrBVEg
-
-
Mashup Score: 2Introducing dorsoventral patterning in adult regenerating lizard tails with gene-edited embryonic neural stem cells - Nature Communications - 3 year(s) ago
Organisms with regenerative capacity typically regrow organs with correct axial patterning, however, regrown lizard tails lack this feature. Here the authors used neural stem cells to induce patterning in regenerating lizard tails and rescued normal skeletal morphology.
Source: Nature CommunicationsCategories: General Medicine News, Latest HeadlinesTweet-
The Lozito group @USCStemCell used neural stem cells to induce patterning in regenerating lizard tails and restpre normal skeletal morphology. @KeckSchool_USC @KeckMedUSC #regeneration #patterning #stemcells https://t.co/5PRTJPPs1t
-
-
Mashup Score: 1Regeneration Research Finds a Rich Model in a Marine Worm - 3 year(s) ago
Scientists at Harvard University have generated a toolkit to enable in-depth study of cellular and molecular mechanisms in a species of marine worms called Hofstenia miamia (also called the three-banded panther worm) that are capable of extensive whole-body regeneration. The new transgenically-enabled model system will facilitate understanding of a major animal lineage that is largely unstudied….
Categories: Future of Medicine, Latest HeadlinesTweet-
Scientists at @Harvard have generated a toolkit to enable in-depth study of cellular and molecular mechanisms in a species of marine worms called Hofstenia miamia that are capable of extensive whole-body #regeneration. Learn more: https://t.co/KFBwQthvfQ https://t.co/71GPL164ul
-
-
Mashup Score: 4Introducing dorsoventral patterning in adult regenerating lizard tails with gene-edited embryonic neural stem cells - Nature Communications - 3 year(s) ago
Organisms with regenerative capacity typically regrow organs with correct axial patterning, however, regrown lizard tails lack this feature. Here the authors used neural stem cells to induce patterning in regenerating lizard tails and rescued normal skeletal morphology.
Source: Nature CommunicationsCategories: General Medicine News, Latest HeadlinesTweet-
The Lozito group @USCStemCell used neural stem cells to induce patterning in regenerating lizard tails and restpre normal skeletal morphology. @KeckSchool_USC @KeckMedUSC #regeneration #patterning #stemcells https://t.co/5PRTJPPs1t
-
What cell properties aid cell #regeneration after exposure to ionizing radiation? (for example, after #CancerTreatment) Ledru et al identify 6 genes in #Drosophila that increase or decrease the regenerative potential of cells #genetics #radiation https://t.co/OIM9nq98FC