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Mashup Score: 0
Chimeric antigen receptor (CAR) T cells are ineffective against solid tumors with immunosuppressive microenvironments. To overcome suppression, we engineered circuits in which tumor-specific synNotch receptors locally induce production of the cytokine IL-2. These circuits potently enhance CAR T cell …
Source: PubMedCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 7Periodontal Inflamed Surface Area (PISA) associates with composites of salivary cytokines - 1 year(s) ago
Background Periodontal disease (PerioD) is a chronic, complex inflammatory condition resulting from the interaction between subgingival dysbiotic bacteria and the host immune response leading to local inflammation. Since periodontal inflammation is characterized by multiple cytokines effects we investigated whether Periodontal Inflamed Surface Area (PISA), a continuous measure of clinical…
Source: journals.plos.orgCategories: General Medicine News, Latest HeadlinesTweet-
Gum #inflammation parallels novel '#cytokine score' @PLOSONE https://t.co/udfQxJOx7m https://t.co/vDUH7H8P5n
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Mashup Score: 0Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis - BMC Medicine - 1 year(s) ago
Background Dual-specificity phosphatases (DUSPs) can dephosphorylate both tyrosine and serine/threonine residues of their substrates and regulate T cell-mediated immunity and autoimmunity. The aim of this study was to investigate the potential roles of DUSPs in ankylosing spondylitis (AS). Methods Sixty AS patients and 45 healthy controls were enrolled in this study. Associations of gene…
Source: BioMed CentralCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of #AnkylosingSpondylitis - https://t.co/om0fRsDaS1 Clinical sampling and animal modelling involves #DUSP #TCell in #spondyloarthritis #rheumtwitter #inflammation #cytokine https://t.co/PR2XhxM8ph
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Mashup Score: 5Current issue: Trends in Immunology - 1 year(s) ago
Spiking SARS-CoV-2 antiviral immunity in the respiratory tractThe COVID-19 pandemic enabled the successful launch of mRNA-based vaccines that, when given intramuscularly, elicit spike-specific antibodies and prevent severe disease, but do not promote mucosal immunity. New data suggest how to boost systemic immunity and elicit pulmonary immunity in a way that more effectively controls infection…
Source: www.cell.comCategories: Allergy-Immunology, Latest HeadlinesTweet-
Read the Feb issue @TrendsImmuno ! #SARSCoV2, #Blackdeath, #cytokine release syndrome, type 2 #diabetes, tolerogenic dendritic cells, #RAG scanning & #antibody diversity, #GATA6 cavity #macrophages in infection & injury, & more!! https://t.co/UbIxpvkNNP https://t.co/uC2JgNdTqN
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Mashup Score: 2Helminth Infection–Induced Increase in Virtual Memory CD8 T Cells Is Transient, Driven by IL-15, and Absent in Aged Mice - 1 year(s) ago
Key Points. Helminth infection–driven increases in TVM cells are caused by IL-15.The impact on TVM cells after helminth infection is not maintained into old age
Categories: Allergy-Immunology, Latest HeadlinesTweet-
#JI_TopRead from @NicoleLaGruta1 @TabiHussain @DrQuinn4realz @AngelaSciences @MonashBDI | #Age-associated deficits in #cytokine signaling are associated with dysfunction in virtual memory #Tcells and #parasiticimmunity | #ReadTheJI #immunology👉 https://t.co/J86RSOdd0Y https://t.co/vxHn4mJwR0
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Mashup Score: 0
Cytokine-expressing genes were silenced in a recent Vanderbilt University Medical Center study.
Source: Dermatology TimesCategories: Dermatology, Latest HeadlinesTweet-
#Cytokine-expressing #genes were silenced in a recent Vanderbilt University Medical Center study. https://t.co/Jx6zxymWUb
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Mashup Score: 4E-cigarette exposure augments murine abdominal aortic aneurysm development: role of Chil1 - 1 year(s) ago
AbstractAims. Abdominal aortic aneurysm (AAA) is a common cardiovascular disease with a strong correlation to smoking, although underlying mechanisms have been
Source: OUP AcademicCategories: Cardiology News and Journals, Latest HeadlinesTweet-
Vaping an #aneurysm? #Ecigarette #nicotine exposure⬆️ abdominal aortic #aneurysm development in mice via vascular #inflammation🔥, #oxidative stress & the #cytokine Chil1 https://t.co/Th38zZ8oWP @CVR_TomaszGuzik @DrMikeDrozd @glenpyle #AAA #vape #CVD #CardiovascularResearch https://t.co/QwPmm4Bl8N
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Mashup Score: 0
In the era of organ machine perfusion, experimental models to optimize reconditioning of (marginal) liver grafts are needed. Although the relevance of cytokine signatures in liver transplantation has been analyzed previously, the significance of molecular monitoring during normothermic machine perfusion (NMP) remains elusive. Therefore, we developed a porcine model of cold ischemic liver graft…
Source: FrontiersCategories: Latest Headlines, TransplantationTweet-
Monitoring of #cytokine profiles and damage-associated #molecular patterns during #machine #perfusion and #reconditioning of #liver #grafts might serve as useful biomarkers for detection of #inflammation and relevant #IRI @ChSFalk1 https://t.co/YCMbjTf3E4 https://t.co/ygOK4A76Nf
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Mashup Score: 0Cytokines and receptors in cancer immunotherapy - 2 year(s) ago
Thursday, August 25, 2022 at 3:00 PM British Summer Time.
Source: event.on24.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
This upcoming @MyBioTechniques webinar discusses the current landscape of #cytokine-based cancer #immunotherapy and you do not want to miss it! What are you waiting for? Register now >>> https://t.co/eSf63D6qMB https://t.co/SlpIAQw6Xr
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Mashup Score: 0Defects in Long-Term APC Repopulation Ability of Adult Human Bone Marrow Hematopoietic Stem Cells (HSCs) Compared with Fetal Liver HSCs - 2 year(s) ago
This article is featured in Top Reads , p.[][1] [1]: /lookup/volpage/208/1515
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
Distinguished Fellow of AAI Megan Sykes @Columbia | #Adultbonemarrow can be optimized with #cytokine & niche support in creation of personalized immune mice #hematopoiesis #transplantation @CCTI_NYC #DFAAI #FreeToRead https://t.co/V4AvMSW2mt https://t.co/CIj1Cq0LyV
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SCI member Chris Garcia and others found that synthetic #cytokine production circuits may yield better CAR-T targeting/function in hostile tumor microenvironments.https://t.co/dMYZKLg2eb #CellTherapy #Tcells https://t.co/GaDzEAq60p