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    Advances in cutaneous squamous cell carcinoma - PubMed - 7 month(s) ago

    Human malignancies arise predominantly in tissues of epithelial origin, where the stepwise transformation from healthy epithelium to premalignant dysplasia to invasive neoplasia involves sequential dysregulation of biological networks that govern essential functions of epithelial homeostasis. Cutane …

    Source: pubmed.ncbi.nlm.nih.gov
    Categories: Latest Headlines, Oncologists1
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      SCIDirector

      SCI members Jean Tang, Susan Swetter, Kavita Sarin & others review advances in #CutaneousSquamousCellCarcinoma. Understanding the interplay between genetic drivers & the #TumorMicroenvironment is a current focus for prevention & treatment strategies. https://t.co/IhMbMneKhx #cSCC https://t.co/XC2T1WWLi2

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    LabLinks: Targeting the tumor microenvironment - 7 month(s) ago

    Join us for this free in-person event, a collaboration between Netherlands Cancer Institute and Cell Press Monday, November 13, 2023, 8:30 – 17:30 CET Netherlands Cancer Institute Piet Borst Auditorium Plesmanlaan 121, Amsterdam The Netherlands Activation of endogenous immune responses by immune checkpoint blockade (ICB) has revolutionized cancer therapy and has become standard of care for several cancer types. However, many patients do not respond to ICB or other forms of immunotherapy or develop

    Source: info.cell.com
    Categories: General Medicine News, Latest Headlines
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      CellPressNews

      Together with colleagues @NKI_nl, we’ll be hosting this one-day symposium aimed at better understanding the interactions within the #tumormicroenvironment @Cancer_Cell @CellReports @CellRepMed Register here: https://t.co/uT2wRwrjtX https://t.co/UfqclD6pff

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    Validate User - 9 month(s) ago

    We are sorry, but we are experiencing unusual traffic at this time. Please help us confirm that you are not a robot and we will take you to your

    Source: aacrjournals.org
    Categories: Hem/Onc News and Journals, Latest Headlines
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      CR_AACR

      From the August 1 issue— #BRCA1 Insufficiency Induces a Hypersialylated Acidic #TumorMicroenvironment That Promotes #Metastasis and #Immunotherapy Resistance, by X. Shu et al. https://t.co/VupzHA2KSx @UM_1981 https://t.co/ikrdF1XUGu

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    Fueling the Tumor Microenvironment with Cancer-Associated Adipocytes - 12 month(s) ago

    Abstract. Despite their abundance throughout the body, adipocytes are often ignored for their contributions within the tumor microenvironment (TME). However, their role in fueling cancer is becoming increasingly apparent as interest in the TME has seen remarkable advances in recent years. A seminal study by Dirat and colleagues highlighted the essential impact of the peritumoral adipose tissue in…

    Source: American Association for Cancer Research
    Categories: Hem/Onc News and Journals, Latest Headlines
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      CR_AACR

      #ICYMI— Read the Landmark commentary, by @DanielaQuail. Fueling the #TumorMicroenvironment with Cancer-Associated Adipocytes. https://t.co/20lL2Wzxig https://t.co/nKIWXZtUqD

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    Fueling the Tumor Microenvironment with Cancer-Associated Adipocytes - 1 year(s) ago

    Abstract. Despite their abundance throughout the body, adipocytes are often ignored for their contributions within the tumor microenvironment (TME). However, their role in fueling cancer is becoming increasingly apparent as interest in the TME has seen remarkable advances in recent years. A seminal study by Dirat and colleagues highlighted the essential impact of the peritumoral adipose tissue in…

    Source: American Association for Cancer Research
    Categories: Hem/Onc News and Journals, Latest Headlines
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      CR_AACR

      Don't miss the Landmark commentary by @DanielaQuail in the latest issue— Fueling the #TumorMicroenvironment with Cancer-Associated Adipocytes. https://t.co/J7dYFC7QSQ https://t.co/ahsSqpwmyR

  • Mashup Score: 1
    Single-cell transcriptome profiling of the stepwise progression of head and neck cancer - Nature Communications - 1 year(s) ago

    Head and neck squamous cell carcinomas (HNSCCs) undergo a stepwise progression from normal tissues. In order to better understand the molecular mechanisms behind such progression, here the authors profile HNSCC tumors at different stages using single-cell RNA-seq, and observe the role of interactions with the tumor microenvironment.

    Source: Nature
    Categories: General Medicine News, Latest Headlines
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      NatureComms

      #scRNAseq analysis of #HeadAndNeckCancer at different stages reveals molecular profiles during stepwise progression from normal tissues and interactions with the #TumorMicroenvironment #CancerResearch @natrescancer https://t.co/px1O8DpmO1 https://t.co/5CcTLBQRkq

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