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Mashup Score: 0Revisiting the Role of Carnitine in Heart Disease Through the Lens of the Gut Microbiota - PubMed - 8 hour(s) ago
L-Carnitine, sourced from red meat, dairy, and endogenous synthesis, plays a vital role in fatty acid metabolism and energy production. While beneficial for cardiovascular, muscular, and neural health, its interaction with the gut microbiota and conversion into trimethylamine (TMA) and trimethylamin …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, Partners & KOLsTweet
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Mashup Score: 3
Renal nitrogen metabolism primarily involves urea and ammonia metabolism, and is essential to normal health. Urea is the largest circulating pool of nitrogen, excluding nitrogen in circulating proteins, and its production changes in parallel to the degradation of dietary and endogenous proteins. In …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, NephrologyTweet
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Mashup Score: 5
For the mammographic screening regimens considered that begin at age 40 years, this risk is small compared with the expected mortality reduction achievable through screening. The risk of radiation-induced breast cancer should not be a deterrent from mammographic screening of women over the age of 40 …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, General HCPsTweet
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Mashup Score: 10Interleukin-1 Blockade in Patients With ST-Segment Elevation Myocardial Infarction Across the Spectrum of Coronary Artery Disease Complexity - PubMed - 16 hour(s) ago
Patients with ST-segment elevation myocardial infarction (STEMI) and complex coronary artery disease (CAD) face a poor prognosis, including increased heart failure (HF) risk. Phase 2 clinical trials of anakinra have shown inhibition of the acute inflammatory response and prevention of HF after STEMI …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 0Relationship Between Dietary Nutrient Intake and Autophagy-Related Genes in Obese Humans: A Narrative Review - PubMed - 18 hour(s) ago
Obesity is one of the world’s major public health challenges. Its pathogenesis and comorbid metabolic disorders share common mechanisms, such as mitochondrial or endoplasmic reticulum dysfunction or oxidative stress, gut dysbiosis, chronic inflammation and altered autophagy. Numerous pro-autophagy d …
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Mashup Score: 28Estimated Effect of Restarting Renin-Angiotensin System Inhibitors after Discontinuation on Kidney Outcomes and Mortality - PubMed - 1 day(s) ago
Restarting RASi after discontinuation was associated with a lower risk of kidney outcomes and mortality but not related to the incidence of hyperkalemia.
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, NephrologyTweet
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Mashup Score: 3Stopping Renin-Angiotensin System Inhibitors in Patients with Advanced CKD and Risk of Adverse Outcomes: A Nationwide Study - PubMed - 1 day(s) ago
In this nationwide observational study of people with advanced CKD, stopping RAS inhibition was associated with higher absolute risks of mortality and major adverse cardiovascular events, but also with a lower absolute risk of initiating KRT.
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, NephrologyTweet
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Mashup Score: 44
National Institutes of Health. (PROSPERO: CRD42022307589).
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, NephrologyTweet
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Mashup Score: 77
Optimizing Renin-Angiotensin System Inhibitor Use in CKD
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, NephrologyTweet
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Mashup Score: 2
Level III, retrospective comparative prognostic case-control study.
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, RheumatologyTweet
TMAO! Revisiting the Role of Carnitine in Heart Disease Through the Lens of the Gut Microbiota https://t.co/ks8OcYLgza