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Mashup Score: 0Lithuanian soprano Asmik Grigorian makes belated Metropolitan Opera debut as Madame Butterfly - 2 hour(s) ago
Opera singer Asmik Grigorian is at the peak of her career, but there’s one major opera venue she hasn’t yet performed at — New York’s Metropolitan Opera.
Source: apnews.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 2One-Year Longitudinal Assessment of Patients With CMT1A Using Quantitative MRI | Neurology - 2 hour(s) ago
Background and ObjectivesIntramuscular fat fraction (FF) assessed using quantitative MRI (qMRI) has emerged as one of the few responsive outcome measures in CMT1A suitable for future clinical trials. This study aimed to identify the relevance of multiple …
Source: www.neurology.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 1Identification of Early Hippocampal Dynamics during Recognition Memory with Independent Component Analysis - 3 hour(s) ago
The hippocampus is generally considered to have relatively late involvement in recognition memory, its main electrophysiological signature being between 400 and 800 ms after stimulus onset. However, most electrophysiological studies have analyzed the hippocampus as a single responsive area, selecting only a single-site signal exhibiting the strongest effect in terms of amplitude. These classical approaches may not capture all the dynamics of this structure, hindering the contribution of other hippocampal sources that are not located in the vicinity of the selected site. We combined intracerebral electroencephalogram recordings from epileptic patients with independent component analysis during a recognition memory task involving the recognition of old and new images. We identified two sources with different responses emerging from the hippocampus: a fast one (maximal amplitude at ∼250 ms) that could not be directly identified from raw recordings and a latter one, peaking at ∼400 ms. The
Source: www.eneuro.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 1
Purpose Tandem occlusion, in which the intracranial artery is obstructed along with proximal carotid occlusive or stenotic lesions, occurs in 10–15% of patients…
Source: journals.sagepub.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 2
Purpose Endovascular treatment (EVT) of acute ischemic stroke caused by large-vessel occlusion (AIS-LVO) over 24 h of onset remains controversial. This study wa…
Source: journals.sagepub.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 1Modeling Robotic-Assisted Mechanical Thrombectomy Procedures with the CorPath GRX Robot: The Core-Flow Study - 3 hour(s) ago
BACKGROUND AND PURPOSE: Endovascular robotic devices may enable experienced neurointerventionalists to remotely perform endovascular thrombectomy. This study aimed to assess the feasibility, safety, and efficacy of robot-assisted endovascular thrombectomy compared with manual procedures by operators with varying levels of experience, using a 3D printed neurovascular model. MATERIALS AND METHODS: M1 MCA occlusions were simulated in a 3D printed neurovascular model, linked to a CorPath GRX robot in a biplane angiography suite. Four interventionalists performed manual endovascular thrombectomy ( n = 45) and robot-assisted endovascular thrombectomy ( n = 37) procedures. The outcomes included first-pass recanalization (TICI 2c–3), the number and size of generated distal emboli, and procedural length. RESULTS: A total of 82 experimental endovascular thrombectomies were conducted. A nonsignificant trend favoring the robot-assisted endovascular thrombectomy was observed in terms of final rec
Source: www.ajnr.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 1
BACKGROUND AND PURPOSE: Successful post-flow-diverter endoluminal reconstruction is widely believed to require endothelial overgrowth of the aneurysmal inflow zone. However, endothelialization/neointimal overgrowth is a complex process, over which we currently have very limited influence. Less emphasized is vascular remodeling of the target arterial segment, the dynamic response of the vessel to flow-diverter implantation. This process is distinct from flow modifications in covered branches. It appears that basic angiographic methods allow simple and useful observations. The purpose of this article was to quantitatively evaluate observable postimplantation changes in target vessels following deployment of Pipeline endoluminal constructs. MATERIALS AND METHODS: One hundred consecutive adults with unruptured, previously untreated, nondissecting aneurysms treated with the Pipeline Embolization Device with Shield Technology and the availability of follow-up conventional angiography were st
Source: www.ajnr.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 3
BACKGROUND AND PURPOSE: Artificial intelligence (AI) models in radiology are frequently developed and validated using datasets from a single institution and are rarely tested on independent, external datasets, raising questions about their generalizability and applicability in clinical practice. The American Society of Functional Neuroradiology (ASFNR) organized a multi-center AI competition to evaluate the proficiency of developed models in identifying various pathologies on NCCT, assessing age-based normality and estimating medical urgency. MATERIALS AND METHODS: In total, 1201 anonymized, full-head NCCT clinical scans from five institutions were pooled to form the dataset. The dataset encompassed normal studies as well as pathologies including acute ischemic stroke, intracranial hemorrhage, traumatic brain injury, and mass effect (detection of these-task 1). NCCTs were also assessed to determine if findings were consistent with expected brain changes for the patient’s age (task 2: a
Source: www.ajnr.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 17A Systematic Review of the Efficacy and Safety of Tenecteplase Versus Alteplase in Acute Ischemic Stroke: A Time to Pass the Torch - 3 hour(s) ago
Alteplase, a biosynthetic form of human tissue‐type plasminogen activator, is Food and Drug Administration‐approved for the treatment of acute ischemic stroke and currently the standard of care for…
Source: www.ahajournals.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 8Hemorrhage Expansion Rates Before and After Minimally Invasive Surgery for Intracerebral Hemorrhage: Post Hoc Analysis of MISTIE II/III - 3 hour(s) ago
BACKGROUNDStereotactic thrombolysis for evacuation of large spontaneous intracerebral (ICH) and intraventricular hemorrhage (IVH) typically requires stabilizing the hemorrhage preoperatively. We in…
Source: www.ahajournals.orgCategories: General Medicine News, NeurologyTweet
“My only regret is not having booked her sooner,” said Met general manager Peter Gelb. “Asmik is an operatic force of nature, one of the greatest and most complete vocal and acting packages in recent operatic history.” https://t.co/OOqyIbQJQs