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Mashup Score: 0Science Education for the Youth (SEFTY): A Neuroscience Outreach Program for High School Students in Southern Nevada during the COVID-19 Pandemic - 20 hour(s) ago
Laboratory outreach programs for K-12 students in the United States from 2020 to 2022 were suspended or delayed due to COVID-19 restrictions. While Southern Nevada also observed similar closures for onsite programs, we and others hypothesized that in-person laboratory activities could be prioritized after increasing vaccine doses were available to the public and masking was encouraged. Here, we describe how the Laboratory of Neurogenetics and Precision Medicine at the University of Nevada Las Vegas (UNLV) collaborated with administrators from a local school district to conduct training activities for high school students during the COVID-19 pandemic. The Science Education for the Youth (SEFTY) program’s curriculum was constructed to incorporate experiential learning, fostering collaboration and peer-to-peer knowledge exchange. Leveraging neuroscience tools from our UNLV laboratory, we engaged with 117 high school applicants from 2021 to 2022. Our recruitment efforts yielded a diverse c
Source: www.eneuro.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 1Identification of Early Hippocampal Dynamics during Recognition Memory with Independent Component Analysis - 1 day(s) ago
The hippocampus is generally considered to have relatively late involvement in recognition memory, its main electrophysiological signature being between 400 and 800 ms after stimulus onset. However, most electrophysiological studies have analyzed the hippocampus as a single responsive area, selecting only a single-site signal exhibiting the strongest effect in terms of amplitude. These classical approaches may not capture all the dynamics of this structure, hindering the contribution of other hippocampal sources that are not located in the vicinity of the selected site. We combined intracerebral electroencephalogram recordings from epileptic patients with independent component analysis during a recognition memory task involving the recognition of old and new images. We identified two sources with different responses emerging from the hippocampus: a fast one (maximal amplitude at ∼250 ms) that could not be directly identified from raw recordings and a latter one, peaking at ∼400 ms. The
Source: www.eneuro.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 1
Most neuroeconomic research seeks to understand how value influences decision-making. The influence of reward type is less well understood. We used functional magnetic resonance imaging (fMRI) to investigate delay discounting of primary (i.e., food) and secondary rewards (i.e., money) in 28 healthy, normal-weighted participants (mean age = 26.77; 18 females). To decipher differences in discounting behavior between reward types, we compared how well-different option-based statistical models (exponential, hyperbolic discounting) and attribute-wise heuristic choice models (intertemporal choice heuristic, dual reasoning and implicit framework theory, trade-off model) captured the reward-specific discounting behavior. Contrary to our hypothesis of different strategies for different rewards, we observed comparable discounting behavior for money and food (i.e., exponential discounting). Higher k values for food discounting suggest that individuals decide more impulsive if confronted with food
Source: www.eneuro.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 7Replicability and Preregistration - 3 day(s) ago
Replicability in science, despite being considered a core component of scientific practice, is low across the scientific fields. One possible solution is Registered Reports, an alternative publishing model where peer review is conducted prior to data collection; a study is accepted based on the strength of its hypothesis and methodology, rather than the novelty of the findings or the “story.”
Source: neuronline.sfn.orgCategories: General Medicine News, NeurologyTweet-
Register for this free webinar on May 8 to hear @eNeuroEiC, Jose Abisambra, co-EiC of @ELSneuroscience journal Brain Research, & @randalljellis discuss replicability issues in science & how #RegisteredReports can support rigorous & reproducible research. https://t.co/mQBRQfcszh https://t.co/KLkARIC4Xg
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Mashup Score: 1Alpha and Beta Oscillations Differentially Support Word Production in a Rule-Switching Task - 3 day(s) ago
Research into the role of brain oscillations in basic perceptual and cognitive functions has suggested that the alpha rhythm reflects functional inhibition while the beta rhythm reflects neural ensemble (re)activation. However, little is known regarding the generalization of these proposed fundamental operations to linguistic processes, such as speech comprehension and production. Here, we recorded magnetoencephalography in participants performing a novel rule-switching paradigm. Specifically, Dutch native speakers had to produce an alternative exemplar from the same category or a feature of a given target word embedded in spoken sentences (e.g., for the word “tuna”, an exemplar from the same category—“seafood”—would be “shrimp”, and a feature would be “pink”). A cue indicated the task rule—exemplar or feature—either before (pre-cue) or after (retro-cue) listening to the sentence. Alpha power during the working memory delay was lower for retro-cue compared with that for pre-cue in the
Source: www.eneuro.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 1Prefrontal Regulation of Safety Learning during Ethologically Relevant Thermal Threat - 5 day(s) ago
Join this interactive session as Anthony Burgos-Robles and Ada Felix-Ortiz discuss their paper, “Prefrontal Regulation of Safety Learning during Ethologically Relevant Thermal Threat”, with eNeuro Editor-in-Chief Christophe Bernard.
Source: neuronline.sfn.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 1
Neuroprotection after injury or in neurodegenerative disease remains a major goal for basic and translational neuroscience. Retinal ganglion cells (RGCs), the projection neurons of the eye, degenerate in optic neuropathies after axon injury, and there are no clinical therapies to prevent their loss or restore their connectivity to targets in the brain. Here we demonstrate a profound neuroprotective effect of the exogenous expression of various Ca2+/calmodulin-dependent protein kinase II (CaMKII) isoforms in mice. A dramatic increase in RGC survival following the optic nerve trauma was elicited by the expression of constitutively active variants of multiple CaMKII isoforms in RGCs using adeno-associated viral (AAV) vectors across a 100-fold range of AAV dosing in vivo. Despite this neuroprotection, however, short-distance RGC axon sprouting was suppressed by CaMKII, and long-distance axon regeneration elicited by several pro-axon growth treatments was likewise inhibited even as CaMKII f
Source: www.eneuro.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 1Prefrontal Regulation of Safety Learning during Ethologically Relevant Thermal Threat - 6 day(s) ago
Join this interactive session as Anthony Burgos-Robles and Ada Felix-Ortiz discuss their paper, “Prefrontal Regulation of Safety Learning during Ethologically Relevant Thermal Threat”, with eNeuro Editor-in-Chief Christophe Bernard.
Source: neuronline.sfn.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 1eNeuro at Ten: Just Warming Up - 8 day(s) ago
Dear friends, As we approach the tenth anniversary of eNeuro at the close of 2024, it strikes me that 10-year-olds are known for their boundless energy and insatiable curiosity. Much like a child at this pivotal age, eNeuro is far from settling down. Instead, we are just gearing up for the lively and exciting journey ahead. Remember when you were ten? Too old to be considered little, but too young to be taken too seriously. Ten-year-olds are notorious for their enthusiasm, their sudden spurts of growth, and their remarkable ability to never sit still. Likewise, eNeuro is buzzing with energy and a refusal to …
Source: www.eneuro.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 23Structure–Function Interactions in the Hippocampus and Prefrontal Cortex Are Associated with Episodic Memory in Healthy Aging - 9 day(s) ago
Aging comes with declines in episodic memory. Memory decline is accompanied by structural and functional alterations within key brain regions, including the hippocampus and lateral prefrontal cortex, as well as their affiliated default and frontoparietal control networks. Most studies have examined how structural or functional differences relate to memory independently. Here we implemented a multimodal, multivariate approach to investigate how interactions between individual differences in structural integrity and functional connectivity relate to episodic memory performance in healthy aging. In a sample of younger ( N = 111; mean age, 22.11 years) and older ( N = 78; mean age, 67.29 years) adults, we analyzed structural MRI and multiecho resting-state fMRI data. Participants completed measures of list recall (free recall of words from a list), associative memory (cued recall of paired words), and source memory (cued recall of the trial type, or the sensory modality in which a word w
Source: www.eneuro.orgCategories: General Medicine News, NeurologyTweet
#eNeuro | Science Education for the Youth (SEFTY): A Neuroscience Outreach Program for High School Students in Southern Nevada during the COVID-19 Pandemic https://t.co/7pZ6EnLacl