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Mashup Score: 0In survivors of acute COVID-19, CV risk, burden ‘substantial’ - 2 year(s) ago
Compared with controls, survivors of acute COVID-19 have elevated CV risks and burdens at 1 year, even if they were not hospitalized for COVID-19, researchers reported in Nature Medicine. “Our results provide evidence that the risk and 1-year burden of cardiovascular disease in survivors of acute COVID-19 are substantial,” Yan Xie, MPH, biostatistician in the Clinical Epidemiology
Source: www.healio.comCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 114Heart-disease risk soars after COVID — even with a mild case - 2 year(s) ago
Massive study shows a long-term, substantial rise in risk of cardiovascular disease, including heart attack and stroke, after a SARS-CoV-2 infection.
Source: www.nature.comCategories: Healthcare Professionals, Latest HeadlinesTweet-
Heart-disease risk soars after #COVID19 - even with a mild case. Massive study shows long-term, substantial rise in risk of #cardiovascular disease🫀, including heart attack and stroke, after a #SARS_CoV_2 infection. https://t.co/6B1mdQqfgD https://t.co/ke2Byw6Koz
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Mashup Score: 1Evidence for a mouse origin of the SARS-CoV-2 Omicron variant - 2 year(s) ago
The rapid accumulation of mutations in the SARS-CoV-2 Omicron variant that enabled its outbreak raises questions as to whether its proximal origin occ…
Source: www.sciencedirect.comCategories: Genetics, Latest HeadlinesTweet-
RT @ValerieTeng: Evidence for a mouse origin of the #SARS_CoV_2 -CoV-2 #Omicron variant https://t.co/TOsDoVWbfL #openaccess @ELS_Genetics
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Mashup Score: 11
Question We evaluated whether the time between first respiratory support and intubation of patients receiving invasive mechanical ventilation (IMV) due to COVID-19 was associated with mortality or pulmonary sequelae. Materials and methods Prospective cohort of critical COVID-19 patients on IMV. Patients were classified as early intubation if they were intubated within the first 48 h from the…
Source: BioMed CentralCategories: Critical Care, Latest HeadlinesTweet-
#CritCare #OpenAccess #COVID19: #Intubation delay is associated with an increase in hospital #mortality and worse #pulmonary sequelae https://t.co/v1JdXIpbJx @jlvincen @ISICEM #FOAMed #FOAMcc #BMC #ICU #intubation #respiratory_failure #pneumonia #ARDS #sars_Cov_2 #infection https://t.co/YxLFbHKdrQ
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Mashup Score: 0Antibody affinity maturation and cross-variant activity following SARS-CoV-2 mRNA vaccination: Impact of prior exposure and sex - 2 year(s) ago
This study demonstrates the impact of prior infection on vaccine-induced antibody affinity maturation and difference in antibody affinity between males and females. Further studies are needed to determine whether antibody affinity may contribute to correlates of protection against SARS-CoV-2 and its variants.
Source: EBioMedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
This month, our editor @Hannah_K_Ralph chose to highlight "Antibody affinity maturation and cross-variant activity following #SARS_CoV_2 mRNA vaccination: impact of prior exposure and sex" by J Tang, G Grubbs et al from @US_FDA CBER Read https://t.co/oxGynp1KdJ
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Mashup Score: 1
This multicenter study investigated clinical risk factors associated with the number of long-term post-COVID symptoms.Clinical features, symptoms at h…
Source: www.sciencedirect.comCategories: Hem/Oncs, Latest HeadlinesTweet-
RT @YLeyfman: https://t.co/7Pz60ybQI6 #coronavirus #COVID19 #COVIDVaccination #Covid_19 #pandemic #pandemiclife #COVID #sars_cov_2 #covid1…
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Mashup Score: 6Identification of SARS-CoV-2 S RBD escape mutants using yeast screening and deep mutational scanning: STAR Protocols - 2 year(s) ago
Summary Here, we describe a protocol to identify escape mutants on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) receptor-binding domain (RBD) using a yeast screen combined with deep mutational scanning. Over 90% of all potential single S RBD escape mutants can be identified for monoclonal antibodies that directly compete with…
Source: star-protocols.cell.comCategories: General Medicine News, Latest HeadlinesTweet-
Online now in @STARProtocols: Dr. Timothy A. Whitehead @CUBoulder using #yeast screening and #DeepSequencing to identify #SARS_CoV_2 spike (S) protein escape mutations for anti-S monoclonal antibodies: https://t.co/Jszrufb6w9 https://t.co/tmhZFQcDPJ
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Mashup Score: 4Omicron, the great escape artist - Nature Reviews Immunology - 2 year(s) ago
Less than a month after the sequence of the SARS-CoV-2 Omicron variant was first announced, a number of articles in Nature and Cell examine its immune evasion characteristics.
Source: NatureCategories: Allergy-Immunology, Latest HeadlinesTweet-
five recent articles published in Nature, and three articles in Cell, describe how #OmicronVariant evades antibody responses. Read the summary here: https://t.co/NnfBUGLYJH #SARS_CoV_2 #COVID19
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Mashup Score: 0
Topline results from the randomized EMPATHY Part A study in acute COVID-19 ambulatory patients comparing single intravenous doses of ensovibep, a DARPin antiviral therapeutic candidate vs. placebo, met the primary endpoint of viral load reduction over eight daysThe secondary endpoint of hospitalization and/or ER visits related to COVID-19, or death showed an overall 78% reduction in risk of…
Source: NovartisCategories: Infectious Disease, Latest HeadlinesTweet-
New outpatient early #covid19 therapy with ensovibep, a DARPin antiviral, as a one time IV infusion by @Novartis. This protein therapy, binds/blocks #SARS_CoV_2 78% reduction in ER/hospitalization. 6% (6/99) placebo to 1.3% (4/301) ensovibep. #IDtwitter https://t.co/JuTrw0OVYR
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Mashup Score: 14Anti-influenza T cells in bronchoalveolar microenvironment of critically severe COVID-19 patients - Critical Care - 2 year(s) ago
Research Letter Open Access Published: 20 December 2021 Critical…
Source: BioMed CentralCategories: Critical Care, Latest HeadlinesTweet-
#CritCare #OpenAccess The #co_infection of #COVID_19 with #influenza: another challenge to public health? https://t.co/yvdrHZt4b2 @jlvincen @ISICEM #FOAMed #FOAMcc #BMC #ICU #lung #SARS_CoV_2 #infection #coronavirus https://t.co/9Q8AMXUulr
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Fresh perspective from Jeffey J. Hsu, MD, PhD, FACC on the long-term risk for CVD following even mild #COVID19 infection #SARS_CoV_2 @JeffHsuMD @Nature @UCLAHealth #Cardiotwitter @NatureMedicine @Biostayan @STLOUISVA @HealioPulm #Cardiotwitter https://t.co/a1k3pQCMp0