Nature Reviews Immunology – A preprint by Makris et al. shows that podoplanin is a key regulator of the functions of fibroblastic reticular cells in lymph nodes, by modulating interactions with…

Nature Reviews Immunology – Besides its beneficial effects against infection, trained immunity has recently been implicated in inflammation-related disorders and is being exploited in cancer…

Nature Reviews Immunology – The peripheral immune system communicates with the brain through diverse anatomical routes to shape brain physiology. Here we discuss why such diversity is needed and…

Nature Reviews Immunology – Kidney diseases affect millions globally. Advances in understanding immunological mechanisms and disease endotypes have enhanced diagnostic accuracy and treatment…

Nature Reviews Immunology – A study in Science reports that intestinal innate lymphoid cells migrate to the pancreas in response to low blood glucose levels to promote glucagon production.

Nature Reviews Immunology – A phenomenon called ‘autosomal random monoallelic expression’ (aRMAE) may explain phenotypic variability of clinical disease in carriers of mutations that cause…

Nature Reviews Immunology – A study in Cell shows that gasdermin D pores can be transferred from cell to cell via extracellular vesicles and induce pyroptotic cell death in bystander cells.

Nature Reviews Immunology – A preprint by Xu et al. shows that MHC-pseudotyped retroviruses can reprogramme, activate and expand tumour-specific T cell populations in vivo.