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Mashup Score: 15MOGAD Together - 29 day(s) ago
Learn more about MOG antibody disease, connect with others in the rare neuroimmune disorders community, and raise awareness for MOGAD! No matter where you are in the world, we invite you to join us.
Source: wearesrna.orgCategories: General Medicine News, Rare DiseaseTweet
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Mashup Score: 90Increased Intracranial Pressure in Pediatric Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease - 6 month(s) ago
Background and Objectives Elevated intracranial pressure (ICP) in myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD) has been largely unexplored. The objectives of this study were to determine the frequency of increased ICP in MOGAD and its association with disease course and outcomes and to highlight cases requiring medical and/or surgical management of increased ICP. Methods In this retrospective, single-center cohort study, we examined the clinical and paraclinical data from the initial presentation and follow-up data of children diagnosed with MOGAD. In those with opening pressure (OP) measurements, univariate analyses were used to evaluate factors associated with increased ICP, which was defined as OP > 28 cm H2O. We also present a case series of patients with or without OP measurement who required medical and/or surgical management of increased ICP. Results Of 86 children with MOGAD, 43 (50.0%) had an OP recorded and 7 (8.1%) required ICP management. In
Source: nn.neurology.orgCategories: General Medicine News, NeurologyTweet-
This single-center cohort study of pediatric #MOGAD describes the frequency of increased intracranial pressure using lumbar puncture opening pressure measurements and evaluates its association with disease course and outcome. Read the open access article: https://t.co/gXclQ3EfDN https://t.co/puRF4gyB4e
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Mashup Score: 6Neurology Video Journal Club: Multiple Sclerosis/Autoimmune Neurology | American Academy of Neurology Journals - 8 month(s) ago
Join us for this and future episodes to learn from experts as they discuss recent Neurology journal articles and hot topics in the field of neurology. Articles and discussants are selected by the editors of Neurology. Professor of Pediatrics, Director Pediatrics MS and Neuroinflammatory Disorders Program, Senior Scientist, University of Toronto The Hospital for Sick Children Research Daniela Castillo Villagr á n, MD Pediatric Neurologist, Clinical Fellow Pediatric MS & Neuroinflammatory Disorders
Source: www.neurology.orgCategories: Latest Headlines, NeurologyTweet-
Neurology Video Journal Club: Drs. Ann Yeh & Daniela Castillo Villagrán discuss an article about differentiating #MS from AQP4-NMOSD and #MOGAD with imaging. Watch now: https://t.co/3MUkCNCxk5 Read the related article: https://t.co/I96053rJBB @sickkids #NeuroTwitter https://t.co/b49lEmd9OS
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Mashup Score: 42023 RNDS - 8 month(s) ago
The one-day regional in-person educational and advocacy conference for those affected by rare neuroimmune disorders.
Source: SRNACategories: Latest Headlines, Rare DiseaseTweet-
Registration is now open for the 2023 Regional Rare Neuroimmune Disorders Symposium in Dallas, TX on October 7. Hosted by @wearesrna and @utsw, this is a one-day regional educational and advocacy event. Learn more here: https://t.co/AUEGcRbpgl #StrongerTogether #NMOSD #MOGAD
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Mashup Score: 0Navigating Through the Recent Diagnostic Criteria for MOGAD - 1 year(s) ago
International criteria for the diagnosis of myelin oligodendrocyte glycoprotein–associated disease (MOGAD) were published in The Lancet Neurology ® on January 24, 2023.1 The criteria recommend that patients with a clinical event typically associated with MOG antibody (Ab) (optic neuritis, myelitis, acute disseminated encephalomyelitis, cerebral monofocal or polyfocal deficits, brainstem or…
Source: NeurologyCategories: Latest Headlines, NeurologyTweet-
Navigating Through the Recent Diagnostic Criteria for MOGAD: Challenges and Practicalities https://t.co/9nlcKWaL7b #Neurology #NeuroTwitter #MOGAD
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Mashup Score: 8Tumefactive Demyelination in MOG Ab–Associated Disease, Multiple Sclerosis, and AQP-4-IgG–Positive Neuromyelitis Optica Spectrum Disorder - 1 year(s) ago
Background and Objectives Studies on tumefactive brain lesions in myelin oligodendrocyte glycoprotein-immunoglobulin G (IgG)–associated disease (MOGAD) are lacking. We sought to characterize the frequency clinical, laboratory, and MRI features of these lesions in MOGAD and compare them with those in multiple sclerosis (MS) and aquaporin-4-IgG–positive neuromyelitis optica spectrum disorder…
Source: NeurologyCategories: Latest Headlines, NeurologyTweet-
This study characterizes the frequency clinical, laboratory, and MRI features of tumefactive brain lesions in #MOGAD and compares them with those in multiple sclerosis (#MS) and aquaporin-4-IgG–positive neuromyelitis optica spectrum disorder (AQP4+NMOSD). https://t.co/b1VcqhqaaM https://t.co/Mv5ot7x2IF
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Mashup Score: 5MOG Antibody–Associated Disease and Thymic Hyperplasia - 1 year(s) ago
Myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) is a recently described CNS inflammatory disorder that may manifest with optic neuritis, myelitis, seizures, and/or acute disseminated encephalomyelitis. While MOG-specific antibodies in patients with MOGAD are IgG1, a T-cell–dependent antibody isotype, immunologic mechanisms of this disease are not fully understood. Thymic…
Categories: Latest Headlines, NeurologyTweet-
This report from the National Multiple Sclerosis Society Case Conference Proceedings describes a case of #MOGAD associated with thymic hyperplasia in a young adult. Read the open access article: https://t.co/tYVQmdsRbz https://t.co/kaiWIOuR1r
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Mashup Score: 2Impaired Brain Growth in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Acute Disseminated Encephalomyelitis - 1 year(s) ago
Background and Objectives Acute disseminated encephalomyelitis (ADEM) is the most common phenotype in pediatric myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease. A previous study demonstrated impaired brain growth in ADEM. However, the effect of MOG antibodies on brain growth remains unknown. Here, we performed brain volume analyses in MOG-positive and MOG-negative ADEM at…
Categories: Latest Headlines, NeurologyTweet-
In this study, patients with both MOG-positive and MOG-negative pediatric acute disseminated encephalomyelitis showed substantial brain volume loss and impaired brain growth over time, with a more pronounced effect in MOG-negative patients. https://t.co/yjw7MeLx2y #MOGAD https://t.co/qzLTauj2Fz
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Mashup Score: 1Early Immunotherapy and Longer Corticosteroid Treatment Are Associated With Lower Risk of Relapsing Disease Course in Pediatric MOGAD - 1 year(s) ago
Background and Objectives We sought to identify early factors associated with relapse and outcome in paediatric-onset myelin oligodendrocyte glycoprotein antibody-associated disorders (MOGAD). Methods In a multicenter retrospective cohort of pediatric MOGAD (≤18 years), onset features and treatment were compared in patients with monophasic vs relapsing disease (including cases with follow-up ≥12…
Categories: Latest Headlines, NeurologyTweet-
Early Immunotherapy and Longer Corticosteroid Treatment Are Associated With Lower Risk of Relapsing Disease Course in Pediatric #MOGAD: https://t.co/ueEJKZCpYU https://t.co/Hu1Io8jjYl
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Mashup Score: 2Effects of the COVID-19 Pandemic on Patients With NMO Spectrum Disorders and MOG-Antibody–Associated Diseases - 1 year(s) ago
Background and Objectives To evaluate the effects of the coronavirus disease 2019 (COVID-19) pandemic on the life of patients with neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein antibody–associated diseases (MOGAD). Methods This multicenter, cross-sectional study included data of 187 patients recruited from 19 different German and Austrian Neuromyelitis…
Categories: Latest Headlines, NeurologyTweet-
This study evaluated the effects of the #COVID-19 pandemic on the life of patients with neuromyelitis optica spectrum disorders (#NMOSD) and myelin oligodendrocyte glycoprotein antibody–associated diseases (#MOGAD): https://t.co/NVMseoHn55 https://t.co/Lfcc6IfjVp
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Learn about MOG Antibody Disease (#MOGAD), connect with others in the rare neuroimmune disorders community, and raise awareness with @wearesrna! No matter where you are in the world, we invite you to join us. Learn more and sign up: https://t.co/fZ8FnV1Iaw