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Mashup Score: 12An IL-9–pulmonary macrophage axis defines the allergic lung inflammatory environment - 2 year(s) ago
IL-9 promotes allergic inflammation by altering the heterogeneity and function of lung macrophages.
Source: Science ImmunologyCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 7
SLAMF7 is up-regulated on macrophages in inflamed tissues and drives superactivation in inflammatory human disease.
Source: Science ImmunologyCategories: Future of Medicine, Latest HeadlinesTweet-
Amplification of SLAMF7 signaling is key driver of human #macrophage “super-activation” that may contribute to inflammation in #RheumatoidArthritis. https://t.co/f11JzqJsPz @SciImmunology https://t.co/Ce1EdP6jta
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Mashup Score: 87An IL-9–pulmonary macrophage axis defines the allergic lung inflammatory environment - 2 year(s) ago
IL-9 promotes allergic inflammation by altering the heterogeneity and function of lung macrophages.
Source: Science ImmunologyCategories: Future of Medicine, Latest HeadlinesTweet-
The protein IL-9 contributes to #asthma and airway inflammation by promoting interstitial #macrophage responses that support recruitment of #eosinophils, according to new research in @SciImmunology. https://t.co/5T7c0sofvG https://t.co/mi5NgBFMim
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Mashup Score: 14
SLAMF7 is up-regulated on macrophages in inflamed tissues and drives superactivation in inflammatory human disease.
Source: Science ImmunologyCategories: Future of Medicine, Latest HeadlinesTweet-
Amplification of SLAMF7 signaling is key driver of human #macrophage “super-activation” that may contribute to inflammation in #RheumatoidArthritis. https://t.co/f11JzqJsPz @SciImmunology https://t.co/f6yig2M9mE
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Mashup Score: 28An IL-9–pulmonary macrophage axis defines the allergic lung inflammatory environment - 2 year(s) ago
IL-9 promotes allergic inflammation by altering the heterogeneity and function of lung macrophages.
Source: Science ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
IL-9 contributes to #asthma and #airway_inflammation by promoting interstitial #macrophage responses that support recruitment of #eosinophils according to new research. https://t.co/VnUjC8rUl8 https://t.co/iPjNUpLKE1
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Mashup Score: 17
SLAMF7 is up-regulated on macrophages in inflamed tissues and drives superactivation in inflammatory human disease.
Source: Science ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
Amplification of SLAMF7 signaling is key driver of human #macrophage “super-activation” that may contribute to inflammation in #rheumatoid_arthritis. https://t.co/0NVvkcKgg8 https://t.co/ntEK0ZAMv1
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Mashup Score: 0Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses - 2 year(s) ago
Mao et al. showed that phosphorylation and transcriptional upregulation of ASS1 mediated by JAK2 and STAT1, respectively, to deplete citrulline is essential for proinflammatory macrophage activation. High levels of intracellular citrulline resulting from ASS1 inhibition can bind and inhibit JAK2, leading to a blocked innate immune response in macrophages.
Source: Molecular CellCategories: Infectious Disease, Latest HeadlinesTweet-
🖊️ Tsinghua University researchers present evidence in @MolecularCell that citrulline depletion by argininosuccinate synthetase is required for proinflammatory #macrophage activation and immune responses. https://t.co/six4FJCuV0 https://t.co/w3lAChqMCp
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Mashup Score: 6Contents | Science Immunology 7, 67 - 2 year(s) ago
Focus Epithelial tuft cells are major producers of lipid mediators (leukotrienes) that drive allergic inflammation and host defense against worm parasites. (see the related Research Article by Ualiyeva et al.). Reviews …
Source: Science ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
The new January issue of Science #Immunology is out! The cover article describes 3 tissue-resident #macrophage subsets. Other papers focus on cancer immunotherapy with shielded pro-IL-12 and stromal cells in the spleen. Plus more to come: https://t.co/I7FBgG3QGK https://t.co/S2oi6beLj2
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Mashup Score: 1
The anaphylatoxin C5a is core effector of complement activation. C5a exerts potent proinflammatory and immunomodulatory actions through interacting with its C5a receptors, C5aR1 and C5aR2, modulating multiple signaling and functional activities of immune cells. Native C5a contains a large N -linked
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
From the Trent Woodruff lab at @UQ_News | Suggest using recombinant human #C5a should be paired with #C5aR1 inhibitors, or purified/synthetic human C5a to confirm relevant findings https://t.co/RmESi8bU8W #ReadTheJI #immunology #complement #innateimmunology #macrophage https://t.co/S3JswTwy23
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Mashup Score: 0The transcription factor KLF14 regulates macrophage glycolysis and immune function by inhibiting HK2 in sepsis - Cellular & Molecular Immunology - 2 year(s) ago
Sepsis is a heterogeneous syndrome induced by a dysregulated host response to infection. Glycolysis plays a role in maintaining the immune function of macrophages, which is crucial for severely septic patients. However, how the pathways that link glycolysis and macrophages are regulated is still largely unknown. Here, we provide evidence to support the function of KLF14, a novel Krüppel-like…
Source: NatureCategories: Infectious Disease, Latest HeadlinesTweet-
A team of researchers at Shanghai General Hospital identified the transcription factor KLF14 as regulating #macrophage glycolysis and immune function by inhibiting HK2 in #sepsis ⚔️. Check it out now: https://t.co/75XdBWoRap https://t.co/gDgIRv25Qu
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The protein IL-9 contributes to #asthma and airway inflammation by promoting interstitial #macrophage responses that support recruitment of #eosinophils, according to new research in @SciImmunology. https://t.co/5T7c0sofvG https://t.co/Nq2ecKKfFY