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Mashup Score: 2COVID-19 and Asthma Onset in Children - 2 day(s) ago
BACKGROUND AND OBJECTIVES:. Respiratory viral infections increase risk of asthma in infants and children. Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus can cause severe lung inflammation and prolonged respiratory symptoms. We sought to determine whether SARS-CoV-2 infection modified pediatric incident asthma risk.METHODS:. This retrospective cohort study…
Source: publications.aap.orgCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 1The role and impact of viruses on cancer development - 2 day(s) ago
This review focuses on three major aspects of oncoviruses’ role in cancer development. To begin, we discuss their geographic distribution, revealing that seven oncoviruses cause 20% of all human canc…
Source: onlinelibrary.wiley.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 5
Nature Microbiology – IFITM1 can compete with EBV glycoproteins for EphA2 binding and prevent virus entry into epithelial cells, in vitro and in vivo. YTHDF3 suppresses IFITM1 via the…
Source: www.nature.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 6
Nature Communications – HIV exposed but uninfected infants may face an increased risk of serious infection and mortality. In this work, the authors utilise a cohort from rural Zimbabwe to explore…
Source: www.nature.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 2SARS-CoV-2 nsp15 preferentially degrades AU-rich dsRNA via its dsRNA nickase activity - 8 day(s) ago
Abstract. It has been proposed that coronavirus nsp15 mediates evasion of host cell double-stranded (ds) RNA sensors via its uracil-specific endoribonuclea
Source: academic.oup.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 2Medicine Researcher Spotlight - Lee Quinton, PhD - 9 day(s) ago
Researcher Spotlight for Lee Quinton, PhD
Source: www.umassmed.eduCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 3Myeloid C-type lectin receptors in innate immune recognition - 11 day(s) ago
C-type lectin receptors (CLRs) comprise a vast family of proteins, several of which play key roles in the immune system. In this article, Reis e Sousa et al. review the biology of CLRs expressed by myeloid cells and their role in innate immune responses to infection, commensal organisms, and tissue injury or dysfunction.
Source: www.cell.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 1Enteric coronavirus nsp2 is a virulence determinant that recruits NBR1 for autophagic targeting of TBK1 to diminish the innate immune response - 14 day(s) ago
Non-structural protein 2 (nsp2) exists in all coronaviruses (CoVs), while its primary function in viral pathogenicity, is largely unclear. One such enteric CoV, porcine epidemic diarrhea virus (PED…
Source: www.tandfonline.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 2New drug prevents flu-related inflammation and lung damage - 16 day(s) ago
Findings show a newly created drug can prevent runaway inflammation while still allowing the immune system to handle the virus, even when given late into infection.
Source: www.eurekalert.orgCategories: General Medicine News, Infectious DiseaseTweet-
A team including Drs. Avishekh Gautam at @FoxChaseCancer and David Boyd at @StJude shows that a newly developed RIPK3 inhibitor, UH15-38, blocks #influenza A virus-triggered necroptosis in alveolar epithelial cells. 🗞️ https://t.co/VgSqywZEG0 📄 https://t.co/GOKffQp0Gq https://t.co/kBl5uIkv02
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Mashup Score: 8
Nature Immunology – Here the authors identify the transcription factor MEF2C as essential for human NK cell function and viral immunity in mice and humans. This control is exerted via regulation of…
Source: www.nature.comCategories: General Medicine News, Infectious DiseaseTweet
💠Curious about #COVID19 and #asthma onset in children? This study examined children ages 1 to 16 within the 🏥 Children’s Hospital of Philadelphia Care Network who received PCR testing for SARS-CoV-2 between March 1, 2020 and February 28, 2021. 👉 https://t.co/vfRH9gUm1z https://t.co/6k1LBOa2pH