Chronic pancreatitis is a progressive fibroinflammatory disease primarily caused by a complex interplay of environmental and genetic risk factors. It might result in pancreatic exocrine and endocrine insufficiency, chronic pain, reduced quality of life, and increased mortality. The diagnosis is based on the presence of typical symptoms and multiple morphological manifestations of the pancreas, including pancreatic duct stones and strictures, parenchymal calcifications, and pseudocysts. Management of chronic pancreatitis consists of prevention and treatment of complications, requiring a multidisciplinary approach focusing on lifestyle modifications, exocrine insufficiency, nutritional status, bone health, endocrine insufficiency, pain management, and psychological care.

2025 marks the centenary of the Locarno Treaties—a series of treaties between European countries after World War 1, negotiated in October, 1925, in Locarno, Switzerland, and signed in London in December, 1925. These agreements ushered in a period of hopeful optimism and peace for European security: the so-called Spirit of Locarno. Relations were re-established between European neighbours and Germany was accepted into the League of Nations. The Nobel Peace Prize was awarded to the three main architects of the treaties.