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Mashup Score: 9Abscopal response in a patient with fibrolamellar hepatocellular carcinoma following radiotherapy - 12 hour(s) ago
A 17-year-old child with fibrolamellar hepatocellular carcinoma presented for treatment of recurrence in the right hilum and bilateral lungs discovered during routine surveillance imaging; he had reported no symptoms.The patient was first diagnosed at 13 years of age, when he presented with right upper quadrant pain; he underwent an extreme liver resection, and received multiple cycles of chemotherapy to achieve his first remission. Over the next 3 years, he sustained relapses to his peritoneum and brain, warranting further chemotherapy, surgery, and radiotherapy.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 17Türkiye rocked by newborn care scandal - 17 hour(s) ago
A huge criminal investigation is under way following accusations that fraud and substandard care have resulted in the deaths of several babies. Kaya Genc reports from Istanbul.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 12The Warnock Report: 40 years on - 1 day(s) ago
Published in 1984, the Warnock Report gave the embryo a “special status”, enabling medical research. As science and society develops, there are new challenges. Jacqui Thornton reports.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 7Fibrolamellar hepatocellular carcinoma and biopsy-proven right hilar mass and lung nodules - 2 day(s) ago
A 36-year-old man with a 6-month history of asthenia, impotence, loss of libido, polyuria, and polydipsia attended our department; he also reported needing to wake up twice at night to urinate and Raynaud’s phenomenon. On examination, his weight was 69 kg, height 1·79 m with a BMI of 24·1 kg/m2; the patient stated he had recently lost 5 kg. Significant muscle atrophy and a reduction of body hair was noted. He had lymphadenopathy of cervical and inguinal nodes. Neurological examination was normal—he had
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Mashup Score: 51Chronic pancreatitis - 2 day(s) ago
Chronic pancreatitis is a progressive fibroinflammatory disease primarily caused by a complex interplay of environmental and genetic risk factors. It might result in pancreatic exocrine and endocrine insufficiency, chronic pain, reduced quality of life, and increased mortality. The diagnosis is based on the presence of typical symptoms and multiple morphological manifestations of the pancreas, including pancreatic duct stones and strictures, parenchymal calcifications, and pseudocysts. Management of chronic pancreatitis consists of prevention and treatment of complications, requiring a multidisciplinary approach focusing on lifestyle modifications, exocrine insufficiency, nutritional status, bone health, endocrine insufficiency, pain management, and psychological care.
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Mashup Score: 15Physical findings - 2 day(s) ago
I spent most of my 2010 wedding day in the emergency ward of my local hospital. Instead of exchanging vows, I was desperately trying to convince the doctors there not to call elder protective services regarding the woman who was about to become my mother-in-law. She had been preparing for the marriage of her youngest son for weeks. Between cooking for more than 200 guests, pressing all the wedding finery, and trying to educate the American bride who would be joining her family on Vietnamese traditions, she kept telling us she was “so tired”.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 5European health security needs a reboot in 2025 - 3 day(s) ago
2025 marks the centenary of the Locarno Treaties—a series of treaties between European countries after World War 1, negotiated in October, 1925, in Locarno, Switzerland, and signed in London in December, 1925. These agreements ushered in a period of hopeful optimism and peace for European security: the so-called Spirit of Locarno. Relations were re-established between European neighbours and Germany was accepted into the League of Nations. The Nobel Peace Prize was awarded to the three main architects of the treaties.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 42
Explore the current issue of The Lancet, a world leading medical journal published weekly since 1823
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Mashup Score: 14The first 100 days of the mpox response in Africa - 4 day(s) ago
Africa’s low COVID-19 mortality rates concealed important vulnerabilities, including poor health infrastructure and manufacturing constraints,1 highlighting the need for a proactive, continent-wide pandemic response. The emphasis on local solutions to global health challenges was a crucial reason for the Africa Centres for Disease Control and Prevention (CDC) to declare mpox a Public Health Emergency of Continental Security.2 A coordinated and cost-effective continental response platform was created to achieve the 6-month pandemic control goal,3 adopting the Coalition for Epidemic Preparedness Innovations’ 100 Days Mission monitoring framework.
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Mashup Score: 24
During 2000–20, NHS coverage of new drugs displaced more population health than it generated. Our results highlight the inherent trade-offs between individuals who directly benefit from new drugs and those who forgo health due to the reallocation of resources towards new drugs.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
A 17-year-old with fibrolamellar hepatocellular carcinoma presented for treatment of recurrence in the right hilum and bilateral lungs discovered during routine surveillance imaging; he had reported no symptoms. Find out more in a new #TLClinicalPic ➡️ https://t.co/v0kpIe4hJD https://t.co/y9EtocwyA0