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    • Mashup Score: 3
      Personalised gait retraining for medial compartment knee osteoarthritis: a randomised controlled trial - 2 day(s) ago

      Personalised foot angle modifications improve pain, reduce knee loading, and might slow osteoarthritis progression, making them a promising non-surgical treatment option for some individuals with medial compartment knee osteoarthritis.

      Source: www.thelancet.com
      Categories: General Medicine News, Rheumatology
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        TheLancetRheum

        NEW RESEARCH—Personalised gait retraining for medial compartment knee #osteoarthritis: a randomised controlled trial https://t.co/Rej8JQHvG7 @ScottUhlrich @UtahMech #ASB2025 #Biomechanics https://t.co/2RM9zi2P5V

    • Mashup Score: 4
      Expanding the rheumatology lens: should we embrace POTS and post-infectious syndromes? - 7 day(s) ago

      Like many of my colleagues who care for patients with dysautonomia, chronic fatigue syndrome, and infection-associated chronic illness, I stumbled into this work seemingly by accident. As a rheumatology fellow, I was trained to ask sharp, targeted questions to diagnose rheumatic diseases. When patients did not fit a recognisable pattern—when their symptoms, laboratory results, and exam findings did not add up—I would explain, often unhelpfully, that they did not have a rheumatological illness, and send them on their way.

      Source: www.thelancet.com
      Categories: General Medicine News, Rheumatology
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      • Profile photo of 	TheLancetRheum
        TheLancetRheum

        NEW Essay by @BritAdlerMD—Expanding the rheumatology lens: should we embrace POTS and post-infectious syndromes? https://t.co/jFtVD8kNFF https://t.co/JjIeg4ye5l

    • Mashup Score: 17
      Preload deficiency as a treatable cause of fatigue and exercise intolerance in SLE - 8 day(s) ago

      Fatigue and exercise intolerance affect more than 90% of patients with systemic lupus erythematosus (SLE), often persisting despite inactive disease.1 The pathophysiology of the disease remains elusive, leading to substantial disruption in daily life.

      Source: www.thelancet.com
      Categories: General Medicine News, Rheumatology
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        TheLancetRheum

        NEW Correspondence—Preload deficiency as a treatable cause of fatigue and exercise intolerance in #SLE https://t.co/SbRcEhSKUS https://t.co/HE2ZQFkIAP

    • Mashup Score: 7
      Towards sustainable relief in chronic low back pain - 9 day(s) ago

      Non-specific low back pain remains one of the leading global causes of disability, substantially diminishing productivity and quality of life among working-age adults. A subset of individuals develop chronic non-specific low back pain, characterised by persistent functional limitations.1 This group accounts for a disproportionate share of health-care resource use compared with people experiencing acute or subacute episodes.2 When symptoms persist for longer than 12 weeks, neurophysiological adaptations can alter pain processing pathways, leading to a shift in the pain profile from predominantly nociceptive or neuropathic to nociplastic.

      Source: www.thelancet.com
      Categories: General Medicine News, Rheumatology
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        TheLancetRheum

        Towards sustainable relief in chronic low back pain Linked Comment by Dimitrios Lytras https://t.co/0X0AxoAuDF https://t.co/RbeJc5Wfjh

    • Mashup Score: 57
      Cognitive functional therapy with or without movement sensor biofeedback versus usual care for chronic, disabling low back pain (RESTORE): 3-year follow-up of a randomised, controlled trial - 9 day(s) ago

      Treatment sessions of CFT produced sustained effects at 3 years for people with chronic disabling low back pain. These long-term effects are novel and provide the opportunity to markedly reduce the effect of chronic back pain if the intervention can be widely implemented. Implementation requires scaling up of clinician training to increase accessibility and replication studies in diverse health-care systems.

      Source: www.thelancet.com
      Categories: General Medicine News, Rheumatology
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        TheLancetRheum

        NEW RESEARCH—Cognitive functional therapy, with or without movement sensor biofeedback, produced sustained effects at 3 years versus usual care for people with chronic disabling low back pain https://t.co/RGpfT9XT26 https://t.co/pJ34BzlcYH

    • Mashup Score: 8
      Group-based cycling and education for hip osteoarthritis - 14 day(s) ago

      Cost-effective first-line treatment for hip osteoarthritis is crucial given its prevalence.1 Higher-quality clinical guidelines recommend exercise, education, and a weight-loss intervention when appropriate.2 However, room for improvement remains regarding the effect and implementation of this first-line treatment.

      Source: www.thelancet.com
      Categories: General Medicine News, Rheumatology
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        TheLancetRheum

        Group-based cycling and education for hip #osteoarthritis Linked Comment by @KjeldsenTroels & Inger Mechlenburg https://t.co/1lzkzZU5gL https://t.co/zB4H8X4ARB

    • Mashup Score: 25
      Clinical and cost-effectiveness of a cycling and education intervention versus usual physiotherapy care for the treatment of hip osteoarthritis in the UK (CLEAT): a pragmatic, randomised, controlled trial - 14 day(s) ago

      The CHAIN intervention showed superior outcomes compared with usual physiotherapy care, and the feasibility of delivering a low-cost, community-based intervention within the NHS was shown. However, longer-term benefits and broader generalisability warrant further investigation.

      Source: www.thelancet.com
      Categories: General Medicine News, Rheumatology
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      • Profile photo of 	TheLancetRheum
        TheLancetRheum

        NEW RESEARCH—Clinical and cost-effectiveness of a cycling and education intervention versus usual physiotherapy care for the treatment of hip #osteoarthritis in the UK (CLEAT): a pragmatic, randomised, controlled trial https://t.co/qQPU0ZDlSv @twwainwright https://t.co/5IZsyRfg1a

    • Mashup Score: 6
      Effectiveness of treat-to-target tapering of TNF inhibitors for psoriatic arthritis and axial spondyloarthritis in the Netherlands: 24-month follow-up of the DRESS-PS trial - 21 day(s) ago

      Treat-to-target tapering of TNF inhibitors remains effective and safe for the maintenance of low disease activity for up to 2 years in patients with psoriatic arthritis and axial spondyloarthritis. Future research should explore the challenges to implementation of tapering strategies in routine care in these patients.

      Source: www.thelancet.com
      Categories: General Medicine News, Rheumatology
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      • Profile photo of 	TheLancetRheum
        TheLancetRheum

        NEW RESEARCH—Effectiveness of treat-to-target tapering of TNF inhibitors for psoriatic arthritis and axial spondyloarthritis in the Netherlands: 24-month follow-up of the DRESS-PS trial https://t.co/bO2437GYzv @NathandBroeder @maartenskliniek @radboudumc https://t.co/L1SS0YPmrE

    • Mashup Score: 10
      EULAR 2025 - 22 day(s) ago

      Hector Chinoy (University of Manchester, UK) presented phase 2 data from the phase 2/3 ALKIVIA study on the safety and efficacy of efgartigimod (an IgG1 antibody Fc fragment targeting the neonatal Fc receptor) in adults with idiopathic inflammatory myopathies. Patients with dermatomyositis, immune-mediated necrotising myositis, polymyositis, or antisynthetase syndrome were randomly assigned (1:1), stratified by myositis subtype and disease severity, to receive subcutaneous efgartigimod 1000 mg once per week or placebo, in addition to standard-of-care background therapy.

      Source: www.thelancet.com
      Categories: General Medicine News, Rheumatology
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        TheLancetRheum

        NEW—We highlight some of the exciting research developments presented at #EULAR2025 https://t.co/GjDt3saCZN https://t.co/onezo7pB3s

    • Mashup Score: 58
      The Lancet Rheumatology Home Page - 24 day(s) ago

      Explore clinical research, expert reviews, and comment and opinion from The Lancet Rheumatology. A voice for rheumatology specialists worldwide

      Source: www.thelancet.com
      Categories: General Medicine News, Rheumatology
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      • Profile photo of 	TheLancetRheum
        TheLancetRheum

        Our August issue is live! Including calcium pyrophosphate crystal deposition #CPPD, #IgG4-related disease, ANCA-associated #vasculitis, #COVID19 vaccines, plus much more! https://t.co/nv6Ef1MA30 Cover by Grace Russell (@Gracie_25) https://t.co/sY5aTOzVE2

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    The Lancet Rheumatology

    @TheLancetRheum

    The #LancetRheumatology is a clinical #rheumatology journal publishing innovative & practice-changing research & opinion across all #rheumatic & #MSK disorders

    ASCO 2025

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