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Mashup Score: 1Source: journals.aai.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 2Source: link.springer.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Multidimensional #Immunophenotyping of Intraductal #Papillary Mucinous #Neoplasms Reveals Novel T Cell and #Macrophage Signature @eckhoff_austin @DukeSurgery https://t.co/lxsyxds6SV #VisualAbstract @McMastersKelly https://t.co/B2X9AmMgUu
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Mashup Score: 1Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Promotes Macrophage Activation via LDL Receptor-Independent Mechanisms - 1 year(s) ago
Background: Activated macrophages contribute to the pathogenesis of vascular disease. Vein graft failure is a major clinical problem with limited therapeutic options. PCSK9 (proprotein convertase sub
Source: Circulation ResearchCategories: Cardiology News and Journals, Latest HeadlinesTweet-
Katsuki & colleagues demonstrate that circulating #PCSK9 promotes #macrophage activation and experimental vein graft lesion development via #LDL receptor-independent mechanisms. Learn more at https://t.co/UPrDHUBoAf @aikawa_masanori https://t.co/ArV0xD2w7l
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Mashup Score: 6Transcriptional and Immune Landscape of Cardiac Sarcoidosis - 2 year(s) ago
Background: Cardiac involvement is an important determinant of mortality among sarcoidosis patients. Although granulomatous inflammation is a hallmark finding in cardiac sarcoidosis, the precise immu
Source: Circulation ResearchCategories: Cardiology News and Journals, Latest HeadlinesTweet-
Liu et al. demonstrated the cellular diversity of a typical #granuloma in cardiac #sarcoidosis. Learn more about the distinct transcriptional profile and #macrophage composition in this #inflammatory disease at https://t.co/OdwfAt2eFN @LavineLab @wusm_pathology https://t.co/WcyNLP1z51
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Mashup Score: 4A shift in lung macrophage composition is associated with COVID-19 severity and recovery - PubMed - 2 year(s) ago
Although it has been more than 2 years since the start of the coronavirus disease 2019 (COVID-19) pandemic, COVID-19 continues to be a worldwide health crisis. Despite the development of preventive vaccines, therapies to treat COVID-19 and other inflammatory diseases remain a major unmet need in med …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet-
A shift in #lung #macrophage #composition is associated with #COVID-19 #severity and #recovery https://t.co/rGNPX9s6uK https://t.co/VNeGQAGsLs
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Mashup Score: 2
Macrophages have diverse phenotypes and functions due to differences in their origin, location and pathophysiological context. Although their main role in the liver has been described as immunoregulatory and detoxifying, changes in macrophage phenotypes, diversity, dynamics and function have been reported during obesity-related complications such as non-alcoholic fatty liver disease (NAFLD)….
Source: www.nature.comCategories: Endocrinology, Latest HeadlinesTweet-
Emelie BarrebyPing ChenMyriam Aouadi discuss our current understanding of the changes in the proportions and functions of liver #macrophage populations in health and #NAFLD https://t.co/1vCheUlUJe https://t.co/FlKcj27hOI
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Mashup Score: 2CD47 Promotes Autoimmune Valvular Carditis by Impairing Macrophage Efferocytosis and Enhancing Cytokine Production - 2 year(s) ago
Systemic autoantibody-mediated diseases accelerate chronic cardiovascular disease in humans. In the K/B.g7 mouse model of spontaneous autoantibody-mediated inflammatory arthritis, valvular carditis arises in part because of Fc receptor–mediated activation of macrophages, leading to production of
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
#CD47 blockade promotes #macrophage #efferocytosis and reduces the severity of #autoimmune #ValvularCarditis in mice| from Bryce A. Binstadt @umnmedschool & colleagues @Cardio_Start | #ReadTheJI #immunology 👉 https://t.co/LFOAttpFYv https://t.co/xjmqPGK9bH
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Mashup Score: 0Synovial tissue macrophages in joint homeostasis, rheumatoid arthritis and disease remission - Nature Reviews Rheumatology - 2 year(s) ago
In this Review, the authors discuss the characterization of distinct synovial tissue macrophage (STM) populations and their functions in the context of the healthy and arthritic joint. They also describe how distinct STMs are specified, how they respond to danger signals and the clinical implications of understanding STM heterogeneity.
Source: NatureCategories: Latest Headlines, RheumatologyTweet-
#JulyIssue | #FreetoRead for 1 month, Focus issue #Review of #synovialtissue #macrophage populations in #RheumatoidArthritis, and their functions in healthy and arthritic joints Read it here: https://t.co/GRJtHkHpti Part of this Focus issue: https://t.co/UhXDGsPNfc https://t.co/jiTsOel6Eu
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Mashup Score: 3Remodeling of the m6A RNA landscape in the conversion of acute lymphoblastic leukemia cells to macrophages - Leukemia - 2 year(s) ago
Leukemia – Remodeling of the m6A RNA landscape in the conversion of acute lymphoblastic leukemia cells to macrophages
Source: NatureCategories: Future of Medicine, Latest HeadlinesTweet-
Excited to report in @LeukemiaJnl @NaturePortfolio that conversion of B-cell #acute #lymphoblastic #leukemia to #macrophage involves remodeling of #m6A RNA mark #epitranscriptomics in a METTL3 dependent manner, particularly for mRNAs of #ribosomal proteins https://t.co/UKqRliG6kS https://t.co/8I2Enwq4Wm
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Mashup Score: 9Advanced Glycation End Products (AGEs) Inhibit Macrophage Efferocytosis of Apoptotic β Cells through Binding to the Receptor for AGEs - 2 year(s) ago
Pancreatic β cell apoptosis is important in the pathogenesis of type 2 diabetes mellitus (T2DM). Generally, apoptotic β cells are phagocytosed by macrophages in a process known as “efferocytosis.” Efferocytosis is critical to the resolution of inflammation and is impaired in T2DM. Advanced
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
#AdvancedGlycationEndProducts inhibit #macrophage #efferocytosis associated #inflammation from Qing Su at Shanghai Jiaotong University | #ReadTheJI #immunology #VisualAbstract https://t.co/8m1tc9LSab https://t.co/aCJ6ItXcK2
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Leptospira dampen inflammation by preventing #macrophage #celldeath and #pyroptotic #IL1beta release | from @DelphineBonhom Catherine Werts & colleagues @institutpasteur | #ReadTheJI #bacterialimmunity #caspase 👉 https://t.co/P8mevRAhjk https://t.co/Wfq8oSXVkw