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Mashup Score: 0Current issue: Trends in Immunology - 1 year(s) ago
Analyzing the unperturbed HIV-1 T cell reservoirThe latent reservoir for HIV-1 prevents cure but is difficult to characterize due to the low frequency of latently infected cells and the absence of unique markers. Sun et al. used single cell analysis of T cell surface phenotypes to provide evidence for immune selection of reservoir cells.Full-Text HTMLPDF ‘Silent’ flagellin…
Source: www.cell.comCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0A path towards personalized medicine for autoinflammatory and related diseases - Nature Reviews Rheumatology - 1 year(s) ago
Next-generation sequencing has led to the discovery of multiple rare autoinflammatory diseases, together with their corresponding disease-causing mutations, creating opportunities to develop personalized medicine and providing useful insight into more common forms of autoimmunity and autoinflammation.
Source: NatureCategories: Latest Headlines, RheumatologyTweet-
#MarchIssue | #Perspective on next-generation #sequencing for rare autoinflammatory diseases and the opportunities to develop #personalized medicine, providing useful insight into more common forms of #autoimmunity and #autoinflammation https://t.co/jRWdYNvUr3 https://t.co/bWuycOC9lC
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Mashup Score: 0
Previous prospective studies suggest that progression to autoimmune diseases is preceded by metabolic dysregulation but it is not clear which metaboli…
Source: www.sciencedirect.comCategories: Healthcare Professionals, Latest HeadlinesTweet-
Cord serum metabolic signatures of future progression to immune-mediated diseases https://t.co/Na1SAHpiNB #autoimmunity #metablomics #lipidomics #immunity #predisposition " Many similarities in metabolic profiles detected across the #autoimmune diseases"
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Mashup Score: 1Prolidase Deficiency Causes Spontaneous T Cell Activation and Lupus-like Autoimmunity - 1 year(s) ago
Key Points. We demonstrate a causal link between prolidase deficiency and autoimmunity.Loss of PEPD leads to an Ag-independent increase in effector CD8 T cells.
Categories: Allergy-Immunology, Latest HeadlinesTweet-
#AuthorChoice: Prolidase deficiency causes spontaneous #Tcell activation and #lupus-like #autoimmunity | from @BetterKidneys @UniofOxford #FreetoRead #ReadTheJI #immunology 👉 https://t.co/DVHAAXawyY https://t.co/ET5mSdIIKM
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Mashup Score: 6Mechanisms underlying autoimmunity in Down syndrome revealed - 1 year(s) ago
Scientists at the Icahn School of Medicine at Mount Sinai in New York have identified which parts of the immune system go awry and contribute to autoimmune diseases in individuals with Down syndrome. The findings published in the February 22 online issue of Nature.
Source: medicalxpress.comCategories: Allergy-Immunology, Latest HeadlinesTweet-
RT @medical_xpress: Mechanisms underlying #autoimmunity in #Downsyndrome revealed @mountsinainyc @nature @ImmunityCP https://t.co/EynA0lengJ
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Mashup Score: 5Mechanisms underlying autoimmunity in Down syndrome revealed - 1 year(s) ago
Scientists at the Icahn School of Medicine at Mount Sinai in New York have identified which parts of the immune system go awry and contribute to autoimmune diseases in individuals with Down syndrome. The findings published in the February 22 online issue of Nature.
Source: medicalxpress.comCategories: General Medicine News, Latest HeadlinesTweet-
Mechanisms underlying #autoimmunity in #Downsyndrome revealed @mountsinainyc @nature @ImmunityCP https://t.co/EynA0lengJ
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Mashup Score: 2
Key Points. The differentiation of lupus autoantigen-specific B cells relies on glycolysis.These B cells are more glycolytic under Ag-specific than TLR7 stimula
Categories: Allergy-Immunology, Latest HeadlinesTweet-
#JI_TopRead from former #JI_Editor Laurence Morel @UTHealthSA | Antigen-specific #Bcells, but not #Tcells, require #glycolysis during systemic #lupus erythematosus | #ReadTheJI #immunometabolism #autoimmunity 👉 https://t.co/hgnpOSZoeu https://t.co/2CAULZtkO7
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Mashup Score: 0Molecular signatures of intrarenal complement receptors C3AR1 and C5AR1 correlate with renal outcome in human lupus nephritis - 1 year(s) ago
Objective Lupus nephritis is one of the most common and serious complications of systemic lupus erythematosus (SLE). Lupus nephritis is a major cause of kidney failure in patients with SLE, attributed to increased morbidity and mortality. The in situ deposition of intrarenal immune complexes promotes the accumulation of inflammatory cells and causes kidney injury. Methods We here extracted…
Source: Lupus Science & MedicineCategories: Latest Headlines, RheumatologyTweet-
This week on LSM: Here show that #intrarenal expression of #complement #receptor C3AR1 and C5AR1 is correlated with treatment success specifically in class III #lupusnephritis. #Lupus #SLE #Autoimmunity #Rheumatology https://t.co/UHAcgpRsZW
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Mashup Score: 4
UC San Diego study reveals critical insights into the complex biology of tissue-specific T cells, paving the way for a new branch of precision therapeutics in immunity, autoimmunity, and cancer.
Source: EurekAlert!Categories: General Medicine News, Latest HeadlinesTweet-
A new study reveals critical insights into the complex #biology of tissue-specific T cells, paving the way for a new branch of precision #therapeutics @UCSanDiego #immunology #autoimmunity https://t.co/VNHCEliHlK
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Mashup Score: 0Molecular signatures of intrarenal complement receptors C3AR1 and C5AR1 correlate with renal outcome in human lupus nephritis - 1 year(s) ago
Objective Lupus nephritis is one of the most common and serious complications of systemic lupus erythematosus (SLE). Lupus nephritis is a major cause of kidney failure in patients with SLE, attributed to increased morbidity and mortality. The in situ deposition of intrarenal immune complexes promotes the accumulation of inflammatory cells and causes kidney injury. Methods We here extracted…
Source: Lupus Science & MedicineCategories: Latest Headlines, RheumatologyTweet-
This week on LSM: Here show that #intrarenal expression of #complement #receptor C3AR1 and C5AR1 is correlated with treatment success specifically in class III #lupusnephritis. #Lupus #SLE #Autoimmunity #Rheumatology https://t.co/UHAcgpRsZW
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Read @TrendsImmuno March issue! #HIV reservoirs, flagellin& #tolerance, #TLR9 & #lupus, #RIPK1, tumor #gdTcells, #PGE2 & #autoimmunity, #COVID19 &Africa, oxidized #mtDNA, #ADAR1 & #innate immunity, #nutrient deficiency&obesity&immunity, #metabolism &Tcells https://t.co/pZdeTFXvTU https://t.co/xFRoYLTmH9