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Mashup Score: 0Patients hospitalized for rotavirus more likely to develop childhood autoimmune disease - 7 month(s) ago
Children who are hospitalized for rotavirus demonstrate a higher risk for developing juvenile-onset autoimmune diseases, including inflammatory arthritis and vasculitis, according to data published in JAMA Network Open. “Rotavirus infection is a leading cause of mortality and morbidity in infants and young children, and these infections are also linked to autoimmunity,” Eun Kyo Ha,
Source: www.healio.comCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 15Integrated single-cell transcriptomics and epigenomics reveals strong germinal center–associated etiology of autoimmune risk loci - 8 month(s) ago
Single-cell ATAC sequencing maps the cell type–specific regulatory potential of transcription factors and autoimmune disease risk loci.
Source: www.science.orgCategories: Allergy-Immunology, Latest HeadlinesTweet-
A 2021 Research Resource for understanding #autoimmune diseases mapped how #genetic mutations could impact immune cell function. @hamish_king @WJGreenleaf @blizard_inst @StanfordMed 📄: https://t.co/bjkSCeVrM5 #WeekendReads https://t.co/TObtUZv6k3
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Mashup Score: 14The expansion of human T-bethighCD21low B cells is T cell dependent - 8 month(s) ago
T cell–derived IFNγ and CD40L/IL-21R signals are crucial for the differentiation of human T-bethighCD21low B cells.
Source: www.science.orgCategories: Allergy-Immunology, Latest HeadlinesTweet-
A 2021 @UniFreiburg study detailed the development of a #Bcell subset that expands when the adaptive immune system is chronically activated, and is frequently implicated in an array of #autoimmune diseases. Learn more: https://t.co/vcxXzzdCVP #WeekendReads https://t.co/Tj6GYAxvee
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Mashup Score: 1Most Patients With Autoimmune Chronic Spontaneous Urticaria Also Have Autoallergic Urticaria, but Not Vice Versa - 9 month(s) ago
Two endotypes of chronic spontaneous urticaria (CSU) associated with mast cell–activating autoantibodies are described, namely autoallergic chronic spontaneous urticaria (aaCSU; with immunoglobulin E [IgE]–anti-autoallergens) and autoimmune chronic spontaneous urticaria (aiCSU; with IgG–anti-high-affinity receptor for the Fc region of immunoglobulin E [FcεRI]/IgE).
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet-
In Current Issue! Most #Patients With #Autoimmune #Chronic #Spontaneous #Urticaria Also Have #Autoallergic Urticaria, but Not Vice Versa https://t.co/UKKhE4MurK https://t.co/JbCYTxL3D0
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Mashup Score: 1Validate User - 9 month(s) ago
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Source: ashpublications.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
A recent study has revealed that patients with #autoimmune #cytopenias had longer durations of response after induction treatment with #rituximab when it was continued as maintenance therapy compared with no post-treatment rituximab maintenance https://t.co/e9mF4FS2Hg
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Mashup Score: 0Children with Cogan’s syndrome should undergo infectious disease screening, brain MRI - 9 month(s) ago
Children with Cogan’s syndrome should undergo thorough evaluations upon presentation, including screenings for autoimmune and infectious diseases, as well as echocardiography and brain MRI, according to data.
Source: www.healio.comCategories: Latest Headlines, RheumatologyTweet-
"Based on the review of literature we suggest a rational diagnostic work-up for #pediatric CS that should include laboratory #autoimmune and infectious screening" #MedTwitter https://t.co/iImXU1RAqf
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Mashup Score: 0
Although testing for antinuclear antibodies is widely viewed as an effective screening tool for lupus and other autoimmune diseases, many rheumatologists fear that excessive ANA testing does more harm than good. And yet the practice is still often deployed by well-meaning physicians — mostly non-rheumatologists — who may not be aware of the specific heterogenetic nature of lupus,
Source: www.healio.comCategories: Latest Headlines, RheumatologyTweet-
Although testing for antinuclear antibodies is widely viewed as an effective screening tool for #lupus and other #autoimmune diseases, many rheumatologists fear that excessive #ANA testing does more harm than good. @JanetBirdope #MedTwitter https://t.co/hYgWXJb913
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Mashup Score: 4Cutting Edge: Aire Is a Coactivator of the Vitamin D Receptor - 10 month(s) ago
Key Points. The Vdr is expressed in Aire+ medullary thymic epithelial cells.Thymic vitamin D signaling stimulates Aire expression and Aire-dependent gene transc
Categories: Allergy-Immunology, Latest HeadlinesTweet-
#CuttingEdge from @MelicharLab and John H. White @mcgillu | #Autoimmune regulator #Aire is a coactivator of the #VitaminDReceptor #ReadTheJI #immunology 👉 https://t.co/1RGiSA0Ie4 https://t.co/p9UgrIa26s
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Mashup Score: 0Immunocompromise and herpes simplex virus type 1 encephalitis (HSVE): a nationwide cohort and case-control study (S25.009) - 10 month(s) ago
Objective: We aim to determine whether a relationship exists between immunocompromise as defined by autoimmune disease or immunosuppressive and immunomodulatory medications in patients and incident HSVE. Background: Among infectious etiologies of encephalitis, herpes simplex virus type 1 (HSV-1) is commonest. The association between immune status and HSVE is unclear. Using a U.S. Medicaid…
Source: NeurologyCategories: Latest Headlines, RheumatologyTweet-
#BWHRheumatology looks at relationship between #autoimmune disease, immunomodulatory meds and incident HSV encephalitis. Strong assoc. of HSVE w/ autoimmune conditions (HR 2.3) and exposure to immunomodulatory meds (HR 2.0). https://t.co/FXZHGAARDa https://t.co/hB08dGZYjd
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Mashup Score: 0The genetics of autoimmune Addison disease: past, present and future - Nature Reviews Endocrinology - 11 month(s) ago
This article discusses the current understanding of the genetics of autoimmune Addison disease and outlines the autoimmune mechanisms that could underlie the effects on the adrenal cortex.
Source: NatureCategories: Endocrinology, Latest HeadlinesTweet-
Ellen Royrvik and Husebye Eystein discuss the current understanding of the genetics of #autoimmune #Addison disease (£) https://t.co/2WT7ao3Y8q #adrenal https://t.co/1Dve6OWTIS
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❗Clinicians beware ❗ Children hospitalized due to #rotavirus - a common cause of gastroenteritis - exhibited an increased risk for #autoimmune disease, such as inflammatory #arthritis and vasculitis https://t.co/2OzLiCAGLh