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Mashup Score: 27Vasculitis: the promising road ahead - 4 day(s) ago
Vasculitides have long posed significant diagnostic and therapeutic challenges for clinicians due to their complex nature. During the past two decades, the mechanisms driving these conditions have become better understood, offering hope to many patients. Yet, the clinical management of patients with vasculitis remains challenging and treatment options are limited. Where are we on the road to combating these diseases?
Source: www.thelancet.comCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 27Vasculitis: the promising road ahead - 4 day(s) ago
Vasculitides have long posed significant diagnostic and therapeutic challenges for clinicians due to their complex nature. During the past two decades, the mechanisms driving these conditions have become better understood, offering hope to many patients. Yet, the clinical management of patients with vasculitis remains challenging and treatment options are limited. Where are we on the road to combating these diseases?
Source: www.thelancet.comCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 2Taking on Vasculitis, Together: Meet Rodney and Debbie - 4 month(s) ago
To gain a deeper understanding of their journey with ANCA-associated vasculitis (AAV), Amgen recently sat down with Rodney and Debbie to hear their story and what advice they have for others.
Source: www.amgen.comCategories: General Medicine News, PayerTweet-
Explaining ANCA-associated #vasculitis to friends, family, & even doctors can be challenging due to its diverse & sometimes invisible manifestations. ➡️ Read Rodney's story to learn more about the importance of self-advocacy for a rare disease diagnosis: https://t.co/Av2V1qNwMx https://t.co/uSIUyl20Hv
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Mashup Score: 2Taking on Vasculitis, Together: Meet Rodney and Debbie - 5 month(s) ago
To gain a deeper understanding of their journey with ANCA-associated vasculitis (AAV), Amgen recently sat down with Rodney and Debbie to hear their story and what advice they have for others.
Source: www.amgen.comCategories: General Medicine News, PayerTweet-
Explaining ANCA-associated #vasculitis to friends, family, & even doctors can be challenging due to its diverse & sometimes invisible manifestations. ➡️ Read Rodney's story to learn more about the importance of self-advocacy for a rare disease diagnosis: https://t.co/1EVitB5G6h https://t.co/Enoo6j9bgS
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Mashup Score: 2Taking on Vasculitis, Together: Meet Rodney and Debbie - 5 month(s) ago
To gain a deeper understanding of their journey with ANCA-associated vasculitis (AAV), Amgen recently sat down with Rodney and Debbie to hear their story and what advice they have for others.
Source: www.amgen.comCategories: General Medicine News, PayerTweet-
Explaining ANCA-associated #vasculitis to friends, family, & even doctors can be challenging due to its diverse & sometimes invisible manifestations. ➡️ Read Rodney's story to learn more about the importance of self-advocacy for a rare disease diagnosis: https://t.co/1lIxI1JOCZ https://t.co/2UPCTMzn76
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Mashup Score: 3Taking on Vasculitis, Together: Meet Rodney and Debbie - 5 month(s) ago
To gain a deeper understanding of their journey with ANCA-associated vasculitis (AAV), Amgen recently sat down with Rodney and Debbie to hear their story and what advice they have for others.
Source: www.amgen.comCategories: General Medicine News, PayerTweet-
Explaining ANCA-associated #vasculitis to friends, family, & even doctors can be challenging due to its diverse & sometimes invisible manifestations. ➡️ Read Rodney's story to learn more about the importance of self-advocacy for a rare disease diagnosis: https://t.co/Dg5b44IVzC https://t.co/a1dPQ1FeNH
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Mashup Score: 28Data quality and patient characteristics in European ANCA-associated vasculitis registries: data retrieval by federated querying - 5 month(s) ago
Objectives This study aims to describe the data structure and harmonisation process, explore data quality and define characteristics, treatment, and outcomes of patients across six federated antineutrophil cytoplasmic antibody-associated vasculitis (AAV) registries. Methods Through creation of the vasculitis-specific Findable, Accessible, Interoperable, Reusable, VASCulitis ontology, we harmonised the registries and enabled semantic interoperability. We assessed data quality across the domains of uniqueness, consistency, completeness and correctness. Aggregated data were retrieved using the semantic query language SPARQL Protocol and Resource Description Framework Query Language (SPARQL) and outcome rates were assessed through random effects meta-analysis. Results A total of 5282 cases of AAV were identified. Uniqueness and data-type consistency were 100% across all assessed variables. Completeness and correctness varied from 49%–100% to 60%–100%, respectively. There were 2754 (52.1%)
Source: ard.bmj.comCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 0Relapse Risk and Safety of Long-Term Tocilizumab Use Among Patients With Giant Cell Arteritis: A Single-Enterprise Cohort Study - 7 month(s) ago
Objective To evaluate the safety and efficacy of tocilizumab (TCZ) in giant cell arteritis (GCA) in a large North American cohort. Methods Patients with GCA treated with TCZ between January 1, 2010, and May 15, 2020, were retrospectively identified. Kaplan-Meier methods were used to estimate time to TCZ discontinuation and time to first relapse after TCZ discontinuation. Poisson regression models were used to compare annualized relapse rates before, during, and after TCZ use. Age- and sex-adjusted risk factors associated with relapse on and off TCZ and development of adverse events of significant interest (AESIs) were examined using Cox models. Results One hundred fourteen patients (60.5% female) were included with mean (SD) age 70.4 (8.2) years. Median duration from GCA diagnosis to TCZ start was 4.5 months. Median overall duration of TCZ treatment was 2.3 years. Relapse rate prior to TCZ start (0.84 relapses/person-year) was 3-fold reduced while on TCZ (0.28 relapses/person-year; P <
Source: www.jrheum.orgCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 7
Bywaters lesion is a cutaneous vasculitis seen in rheumatoid arthritis.1 A 70-year-old man presenting with polyarthritis and finger papules visited our hospital. The patient had a 12-year history of polyarthritis, and bilateral ulnar deviation developed 5 years prior. Computed tomography indicated interstitial pneumonia, and blood work confirmed a rheumatoid factor level of 2708 (normal < 15) IU/mL and anticyclic citrullinated peptide antibody …
Source: www.jrheum.orgCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 2Temporal Artery Ultrasound for the Diagnosis of Giant Cell Arteritis in the Emergency Department - 8 month(s) ago
Giant cell arteritis (GCA), known as temporal arteritis, is a serious condition requiring immediate treatment to prevent complications. GCA can be difficult to diagnose, especially in emergency department (ED) settings where ophthalmology and rheumatology …
Source: www.ncbi.nlm.nih.govCategories: Latest Headlines, RheumatologyTweet
#Vasculitis: the promising road ahead Read our May editorial https://t.co/Uyk1hUaKzu https://t.co/AJHcOt5Ykn