• Mashup Score: 6

    Telomeres are regions of repetitive nucleotide sequences at the ends of chromosomes. Telomere length is a marker of DNA damage, which is often considered a biomarker for biological ageing, and has also been linked with cardiovascular disease, diabetes, and cancer. Emerging studies have highlighted the role of genetic and environmental factors, and explored the effect of modulating telomere…

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    • #Diabetes, #metabolic disease, and #telomere length https://t.co/LkVS4eyXdo #T1D #T2D #ageing https://t.co/YTLJdvoQLO

  • Mashup Score: 0

    August 17, 2022 — A new research paper was published in Aging (“Aging (Albany NY)” by Medline/PubMed, “Aging-US” by Web of Science) Volume 14, Issue 14, titled, “Common electrocardiogram measures are not associated with telomere length.”  Aging is accompanied by telomere shortening. Increased telomere shortening is considered a marker of premature aging. Cardiac aging results in the development…

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    • @DAICeditor Researchers found that #ECG measures are age-dependent, but not associated with shortened #telomere length as a marker of #biologicalaging: https://t.co/AjFtTEeIIi

  • Mashup Score: 0

    The clock used a simple statistical model, which looked at a certain type of epigenetic modification at just two target sites on DNA.

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    • New ‘#Aging Clock’: #Epigenetic age. https://t.co/ZvPIhtGPad https://t.co/lAjP18NNIC Epigenetic aging is distinct from cellular #senescence, #telomere attrition, genomic instability, and associated with #nutrient sensing, #mitochondria activity and #stemcell composition. #EpiAge https://t.co/XnBwOGwHvP

  • Mashup Score: 4

    Telomeres are regions of repetitive nucleotide sequences at the ends of chromosomes. Telomere length is a marker of DNA damage, which is often considered a biomarker for biological ageing, and has also been linked with cardiovascular disease, diabetes, and cancer. Emerging studies have highlighted the role of genetic and environmental factors, and explored the effect of modulating telomere…

    Tweet Tweets with this article
    • #Diabetes, metabolic disease, and #telomere length https://t.co/LkVS4eQy4W #T1D #T2D #ageing https://t.co/VJMoCb07fw

  • Mashup Score: 3

    Telomeres are an array of repetitive nucleotide sequences located at the end of chromosomes that play a critical role in protecting genome integrity during cell division. A growing body of work has demonstrated, that in combination with environmental and epidemiological factors, rare mutations in the telomere maintenance pathway can lead to telomere shortening resulting in increased risk for…

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    • More #telomere #lungtransplant content with this May Editorial - "Short telomeres in lung transplantation: Known unknowns." https://t.co/DOAW4bGJPb @drsnandavaram

  • Mashup Score: 10

    Author summary The generation of haploid gametes is a hallmark of sexual reproduction. And this is accomplished by a complex, albeit tightly regulated, reductional cell division called meiosis. Although meiosis has been extensively studied in eutherian mammal model species, our understanding of the mechanisms regulating chromosome synapsis, recombination and segregation during meiosis progression…

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    • Marsupial #meiosis is unique 🦘 Marín-Gual et al find novel strategies for sex chromosome pairing, #DNA repair, recombination & transcription They also find an alternative mechanism for the paternal control of #telomere length during prophase I https://t.co/41GkwymoBW