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Mashup Score: 6Diabetes, metabolic disease, and telomere length - 2 year(s) ago
Telomeres are regions of repetitive nucleotide sequences at the ends of chromosomes. Telomere length is a marker of DNA damage, which is often considered a biomarker for biological ageing, and has also been linked with cardiovascular disease, diabetes, and cancer. Emerging studies have highlighted the role of genetic and environmental factors, and explored the effect of modulating telomere…
Categories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 0
August 17, 2022 — A new research paper was published in Aging (“Aging (Albany NY)” by Medline/PubMed, “Aging-US” by Web of Science) Volume 14, Issue 14, titled, “Common electrocardiogram measures are not associated with telomere length.” Aging is accompanied by telomere shortening. Increased telomere shortening is considered a marker of premature aging. Cardiac aging results in the development…
Source: DAICCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 0Genetic Evidence That Alcohol Accelerates Biological Aging - 2 year(s) ago
Researchers from Oxford Population Health have published results from a new genetic-based analysis which suggest that alcohol directly accelerates aging by damaging DNA in telomeres.
Categories: Healthcare Professionals, Latest HeadlinesTweet-
#Genetic Evidence That Alcohol Accelerates Biological #aging https://t.co/XikOXMAmJZ #Alcohol consumption and #telomere length: #Mendelianrandomization clarifies alcohol’s effects https://t.co/uUB6T4GFFg "alcohol dose is important –even reducing drinking could have benefits." https://t.co/OSaKHLMdaH
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Mashup Score: 0Experimental Gene Therapy Increases Lifespan Of Mice By 41 Percent In Telomere Lengthening Study - 2 year(s) ago
Experimental Gene Therapy Increases Lifespan Of Mice By 41 Percent In Telomere Lengthening Study
Source: IFLScienceCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 0What's Your Biological Age? A New 'Aging Clock' Has the Answer - 2 year(s) ago
The clock used a simple statistical model, which looked at a certain type of epigenetic modification at just two target sites on DNA.
Source: Singularity HubCategories: Healthcare Professionals, Latest HeadlinesTweet-
New ‘#Aging Clock’: #Epigenetic age. https://t.co/ZvPIhtGPad https://t.co/lAjP18NNIC Epigenetic aging is distinct from cellular #senescence, #telomere attrition, genomic instability, and associated with #nutrient sensing, #mitochondria activity and #stemcell composition. #EpiAge https://t.co/XnBwOGwHvP
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Mashup Score: 4Diabetes, metabolic disease, and telomere length - 2 year(s) ago
Telomeres are regions of repetitive nucleotide sequences at the ends of chromosomes. Telomere length is a marker of DNA damage, which is often considered a biomarker for biological ageing, and has also been linked with cardiovascular disease, diabetes, and cancer. Emerging studies have highlighted the role of genetic and environmental factors, and explored the effect of modulating telomere…
Categories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 3Short telomeres in lung transplantation: Known unknowns - 2 year(s) ago
Telomeres are an array of repetitive nucleotide sequences located at the end of chromosomes that play a critical role in protecting genome integrity during cell division. A growing body of work has demonstrated, that in combination with environmental and epidemiological factors, rare mutations in the telomere maintenance pathway can lead to telomere shortening resulting in increased risk for…
Categories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 10Strategies for meiotic sex chromosome dynamics and telomeric elongation in Marsupials - 2 year(s) ago
Author summary The generation of haploid gametes is a hallmark of sexual reproduction. And this is accomplished by a complex, albeit tightly regulated, reductional cell division called meiosis. Although meiosis has been extensively studied in eutherian mammal model species, our understanding of the mechanisms regulating chromosome synapsis, recombination and segregation during meiosis progression…
Source: journals.plos.orgCategories: Genetics, Latest HeadlinesTweet
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Mashup Score: 0
Background Prenatal maternal tobacco smoking is a predictor of child attention-deficit/hyperactivity disorder (ADHD) and is associated with offspring telomere length (TL). In this study, we examine the relationship between maternal prenatal smoking, infant TL, and maternal report of early childhood symptoms of ADHD. Methods One-hundred and eighty-one mother-infant dyads were followed…
Source: BioMed CentralCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 2Short telomere length predicts nonrelapse mortality after stem cell transplantation for myelodysplastic syndrome - 2 year(s) ago
Myllymäki and colleagues studied the relationship between pretransplant telomere length and survival following hematopoietic stem cell transplantation (HSCT) fo
Source: American Society of HematologyCategories: Hem/Oncs, Latest HeadlinesTweet
#Diabetes, #metabolic disease, and #telomere length https://t.co/LkVS4eyXdo #T1D #T2D #ageing https://t.co/YTLJdvoQLO