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Mashup Score: 0Considerations for Choosing T Cell Assays during a Pandemic - 10 month(s) ago
Abstract. The appropriate immunosurveillance tools are foundational for the creation of therapeutics, vaccines, and containment strategies when faced with outbr
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0Th1 Cells Alter the Inflammatory Signature of IL-6 by Channeling STAT Transcription Factors to Alu-like Retroelements - 10 month(s) ago
Key Points. Th1 cells alter the transcriptional output of IL-6 during acute inflammation.IL-6 and IFN-γ activities combine to steer tissue responses to inflamma
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Mashup Score: 4Nonbinary Roles for T Follicular Helper Cells and T Follicular Regulatory Cells in the Germinal Center Response - 11 month(s) ago
Abstract. Development of high-affinity Abs in the germinal center (GC) is dependent on a specialized subset of T cells called “T follicular helper” (TFH) cells
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Mashup Score: 1“Killing at a Distance”: CD4+ T Cells on the Attack - 11 month(s) ago
Tumors that escape direct immune targeting remain vulnerable to CD4+ T cell–induced inflammatory cell death.
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Proteogenomic and V(D)J Analysis of Human Decidual T Cells Highlights Unique Transcriptional Programming and Clonal Distribution - 11 month(s) ago
Key Points. scRNA/CITE-seq results show that decidual T cells maintain a unique transcriptome.Decidual T cells overexpress negative regulators of inflammatory p
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Mashup Score: 0An Update on 23andMe's Clinical Trial for 23ME-00610 in Patients - 12 month(s) ago
23andMe reports results of the Phase 1 clinical trial for a potential new cancer therapy, an antibody referred to as 23ME-00610, 23ME’610
Source: 23andMe BlogCategories: Healthcare Professionals, Latest HeadlinesTweet-
An Update on #23andMe’s #ClinicalTrial for 23ME-00610 in Patients https://t.co/2nKiUlTdXA #23ME00610 #CD200R1 #Immunotherapy #Tcells "To all our customers who participate in our research – over 80% of you – you help make advancements like this possible. Thank you. We know that… https://t.co/QIogPgohov https://t.co/O65wEk18xW
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Mashup Score: 5Phenotypic diversity of T cells in human primary and metastatic brain tumors revealed by multiomic interrogation - Nature Cancer - 12 month(s) ago
Joyce and colleagues use bulk and single-cell profiling of T cell phenotypes in human samples from primary brain tumors and brain metastases as a resource for understanding the biology and therapeutic relevance of the brain tumor microenvironment.
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 1
Tissue-resident memory T-cell immunosurveillance is associated with cigarette smoking before tumor onset.
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0ATRA, Crenigacestat Synergistically Augment BCMA on MM, BCMA-CAR T-Cell Efficacy | ASH Clinical News | American Society of Hematology - 1 year(s) ago
Skip Nav Destination April 4, 2023 Katie Robinson is a medical writer based in New York. In a pre-clinical study, all-trans retinoic acid (ATRA) treatment, alone or in combination with crenigacestat, led to enhanced B-cell…
Source: ashpublications.orgCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 7
Schwartz and colleagues show that TH9 cells can respond to bystander cytokines IL-2 and IL-4 to induce antigen-independent expression of IL-9, promoting allergic inflammation. Il9 locus remodeling causes TH9 cell instability, preventing antigen-independent activation in individuals who are nonallergic. Therapeutic targeting of the STAT5/STAT6 activation cascade may provide relief for patients…
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet
#BriefReview by Jaclyn Law & former #JI_editor @Tania_WattsUofT @UofT discussing “Considerations for choosing #TCellAssays during a #pandemic” #ReadTheJI #immunology #SARSCoV2 #TCells #COVID 👉 https://t.co/oqV6IxfztE https://t.co/Y3MuYer0xo