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Mashup Score: 7Non-genetic influences on lipoprotein(a) concentrations - 2 year(s) ago
An elevated level of lipoprotein(a) [Lp(a)] is a genetically regulated, independent, causal risk factor for cardiovascular disease. However, the extensive variability in Lp(a) levels between individuals and population groups cannot be fully explained by genetic factors, emphasizing a potential role for non-genetic factors. In this review, we provide an overview of current evidence on non-genetic…
Source: AtherosclerosisCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 0Muscle Quality Predicts Outcomes after Surgery for Early-Stage Non-Small-Cell Lung Cancer - PubMed - 2 year(s) ago
The skeletal muscle quality evaluated by IMAC could be used to predict survival risk after surgery for early-stage NSCLC.
Source: PubMedCategories: Cardiac Surgery, Latest HeadlinesTweet
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Mashup Score: 0Hsa_circ_0079530/AQP4 Axis Is Related to Non-Small Cell Lung Cancer Development and Radiosensitivity - PubMed - 2 year(s) ago
Circ_0079530 silence repressed cell proliferation, migration, and invasion, and facilitated radiosensitivity in NSCLC cells by mediating miR-409-3p/AQP4 axis.
Source: PubMedCategories: Cardiac Surgery, Latest HeadlinesTweet
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Mashup Score: 1Source: link.springer.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0
While epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have changed the treatment landscape for EGFR mutant (L858R and ex19del)-driven non-small-cell lung cancer (NSCLC), most patients will eventually develop resistance to TKIs. In the case of first- and second-generation TK …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 0Clinical characteristics and prognostic factors of patients with non-small cell lung cancer having HER2 alterations - PubMed - 2 year(s) ago
This study was novel in comprehensively investigating the clinical and molecular characteristics of patients in Chinese and Western populations, and in analyzing the factors affecting the prognosis of Chinese patients. It provided critical data for future therapies against HER2-altered NSCLC.
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 9Accurate liquid biopsy for the diagnosis of non-alcoholic steatohepatitis and liver fibrosis - 2 year(s) ago
Objective Clinical diagnosis and approval of new medications for non-alcoholic steatohepatitis (NASH) require invasive liver biopsies. The aim of our study was to identify non-invasive biomarkers of NASH and/or liver fibrosis. Design This multicentre study includes 250 patients (discovery cohort, n=100 subjects (Bariatric Surgery Versus Non-alcoholic Steato-hepatitis – BRAVES trial); validation…
Source: GutCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 2
Since the approval of PD(L)1i for NSCLC, their use has significantly increased for first-line treatment, especially when used in combination with chemotherapy. A significant proportion of patients received chemotherapy alone.
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 0Environmental pesticide exposure and non-Hodgkin lymphoma survival: a population-based study - BMC Medicine - 2 year(s) ago
Background There is evidence indicating that pesticide exposure is a risk factor for non-Hodgkin lymphoma (NHL) development. However, the association between pesticide exposure and NHL survival is not well-established. Methods Using the California Cancer Registry, we identified patients with a first primary diagnosis of NHL from 2010 to 2016 and linked these patients with CalEnviroScreen 3.0 to…
Source: BioMed CentralCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 2
In early-stage NSCLC with low-risk histologic subtype, a less rigorous nodal assessment was not associated with a worse prognosis. While surgeons should continue to aim for complete resection and thorough nodal assessment, a uniform approach to the extent and invasiveness of nodal assessment may nee …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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