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Mashup Score: 4
It is unclear to what extent genetic testing improves the ability to diagnose familial hypercholesterolaemia (FH). We investigated the percentage with FH among individuals referred to Danish lipid clinics, and evaluated the impact of genetic testing for a diagnosis of FH.
Source: AtherosclerosisCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 1LDL cholesterol targets rarely achieved in familial hypercholesterolemia patients: A sex and gender-specific analysis - 1 year(s) ago
Despite lipid lowering therapy (LLT), reaching LDL-C targets in patients with familial hypercholesterolemia (FH) remains challenging. Our aim was to determine attainment of LDL-C target levels and reasons for not reaching these in female and male FH patients.
Source: AtherosclerosisCategories: Cardiologists, Latest HeadlinesTweet-
LDL-C targets rarely achieved in FH patients: A sex & gender-specific analysis Women w. higher pretreatment LDL & ⬇️ High intensity Statin use @ATHjournal #KnowFH #TreatFH @fhpatienteurope @TheFHFoundation @foundationofnla @nationallipid @NYUCVDPrevent https://t.co/Q88QuIj1mv https://t.co/yWTLVIuLkF
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Mashup Score: 1
High-sensitivity C-reactive protein (hsCRP), a marker for atherosclerotic cardiovascular disease risk, is reduced by bempedoic acid. We assessed the relationship between changes in low-density lipoprotein cholesterol (LDL-C) and hsCRP in relation to baseline statin use.
Source: AtherosclerosisCategories: Cardiologists, Latest HeadlinesTweet-
@CardioIAN #CardioTwitter @pabeda1 https://t.co/fgjo6Bsx8w
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Mashup Score: 11Long-term prognostic implications of hemodynamic and plaque assessment using coronary CT angiography - 1 year(s) ago
Hemodynamic and plaque characteristics can be analyzed using coronary CT angiography (CTA). We aimed to explore long-term prognostic implications of hemodynamic and plaque characteristics using coronary CT angiography (CTA).
Source: AtherosclerosisCategories: Cardiologists, Latest HeadlinesTweet-
Long-term prognostic implications of hemodynamic and #plaque assessment using #yesCCT https://t.co/OjyYvU24yB
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Mashup Score: 0When economy meets physiopathology: A novel cost-effectiveness model finally considers the cumulative effect of LDL cholesterol burden - 1 year(s) ago
Familial hypercholesterolemia (FH) is a prevalent hereditary autosomal dominant lipoprotein metabolic disorder marked by increased levels of LDL-cholesterol (LDL-C) and a higher risk of developing early cardiovascular disease [1]. Heterozygotic FH affects 1 in 250–300 individuals worldwide, and less than 1% of those subjects have been diagnosed to date [2,3].
Source: AtherosclerosisCategories: Cardiologists, Latest HeadlinesTweet-
The average lifetime levels of LDL-C multiplied by the number of years lived define the atherosclerotic burden of any individual. Even lower even earlier is even better. #LDL-c https://t.co/Sc1vHU59Ut
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Mashup Score: 0When economy meets physiopathology: A novel cost-effectiveness model finally considers the cumulative effect of LDL cholesterol burden - 1 year(s) ago
Familial hypercholesterolemia (FH) is a prevalent hereditary autosomal dominant lipoprotein metabolic disorder marked by increased levels of LDL-cholesterol (LDL-C) and a higher risk of developing early cardiovascular disease [1]. Heterozygotic FH affects 1 in 250–300 individuals worldwide, and less than 1% of those subjects have been diagnosed to date [2,3].
Source: AtherosclerosisCategories: Cardiologists, Latest HeadlinesTweet-
When economy meets physiopathology: A novel #CostEffectiveness model finally considers the #cumulative effect of #LDL https://t.co/FG8PnMic5Q
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Mashup Score: 1PCSK9 promotes arterial medial calcification - 1 year(s) ago
A complex interplay among chronic kidney disease (CKD), lipid metabolism and aortic calcification has been recognized. Here we investigated the influence of kidney function on PCSK9 levels and its potential direct action on smooth muscle cells (SMCs) calcification.
Source: AtherosclerosisCategories: Cardiologists, Latest HeadlinesTweet-
#PCSK9i : PCSK9 promotes arterial medial calcification https://t.co/TI85CcCMii with @mariagiovannalupo @MassiRuscica et al ++
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Mashup Score: 0
Familial hypercholesterolemia (FH) variants are associated with higher atherosclerotic cardiovascular disease risk (ASCVD) even when compared with other forms of severe hypercholesterolemia, especially in young people. Lipid lowering therapies (LLT) may change hypercholesterolemia natural history. This study aimed at evaluating factors associated with occurrence of ASCVD in old severe…
Source: AtherosclerosisCategories: Cardiologists, Latest HeadlinesTweet-
Cardiovascular disease onset in old people with severe hypercholesterolemia https://t.co/AI5fiyswhB How LLT changes natural history of FH and severe hypercholesterolemia? Look at old people for hints ! @lalacoutinho35 @marciominame @MBittencourtMD @zorzanelli @hipercol_brasil
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Mashup Score: 2Use of Lipoprotein(a) to improve diagnosis and management in clinical familial hypercholesterolemia - 1 year(s) ago
Lipoprotein(a) (Lp [a]) is an LDL-like particle whose plasma levels are largely genetically determined. The impact of measuring Lp(a) in patients with clinical familial hypercholesterolemia (FH) referred for genetic testing is largely unknown. We set out to evaluate the contribution of (genetically estimated) Lp(a) in a large nation-wide referral population of clinical FH.
Source: AtherosclerosisCategories: Cardiologists, Latest HeadlinesTweet-
RT @SABOURETCardio: Use of #Lipoprotein (a) to improve diagnosis and management in #FH https://t.co/UGjF8VjlSf
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Mashup Score: 2Use of Lipoprotein(a) to improve diagnosis and management in clinical familial hypercholesterolemia - 1 year(s) ago
Lipoprotein(a) (Lp [a]) is an LDL-like particle whose plasma levels are largely genetically determined. The impact of measuring Lp(a) in patients with clinical familial hypercholesterolemia (FH) referred for genetic testing is largely unknown. We set out to evaluate the contribution of (genetically estimated) Lp(a) in a large nation-wide referral population of clinical FH.
Source: AtherosclerosisCategories: Cardiologists, Latest HeadlinesTweet-
Use of #Lipoprotein (a) to improve diagnosis and management in #FH https://t.co/UGjF8VjlSf
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Genetic testing increased the diagnoses of FH from 22% to 37% in patients referred to lipid clinics with hypercholesterolemia suspected of FH in Danish national study #KnowFH . Via @ATHjournal @fhpatienteurope @foundationofnla @TheFHFoundation https://t.co/uilqS3UfFO https://t.co/tdj8CqvXfP