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    Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis - 3 year(s) ago

    Author summary Despite extensive investigation on the roles of CEP55 in tumorigenesis, its physiological role during development has remained largely uncharacterized. Recently, homozygous CEP55 mutations have been linked to two lethal fetal syndromes, MKS-like Syndrome and MARCH, demonstrating the importance of CEP55 in embryogenesis and neural development. These syndromes exhibit multiple severe…

    Source: journals.plos.org
    Categories: Genetics, Latest Headlines
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      PLOSGenetics

      Cep55 is important in embryogenesis and #neural development, but its mechanisms are unknown Rashidieh use KO mouse models and #StemCell organoids to find that that Cep55 regulates neurogenesis and ciliogenesis via the Akt pathway 🔎: https://t.co/D4a60MMQi0 @QIMRBerghofer https://t.co/Hm70qGHHfk

  • Mashup Score: 51
    Emergence of robust self-organized undulatory swimming based on local hydrodynamic force sensing - 3 year(s) ago

    Undulatory swimming represents an ideal behavior to investigate locomotion control and the role of the underlying central and peripheral components in the spinal cord. Many vertebrate swimmers have central pattern generators and local pressure-sensitive receptors that provide information about the surrounding fluid. However, it remains difficult to study experimentally how these sensors influence…

    Source: Science Robotics
    Categories: Future of Medicine, Latest Headlines
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      ScienceMagazine

      A lamprey-inspired #robot replicated the slithering movement of lampreys and eels underwater by aligning an internal #neural circuit—akin to a lamprey’s spinal cord—with external sensors. Read more in @SciRobotics: https://t.co/NNNmqcel4C https://t.co/UVoReeRUwd

  • Mashup Score: 5
    Emergence of robust self-organized undulatory swimming based on local hydrodynamic force sensing - 3 year(s) ago

    Undulatory swimming represents an ideal behavior to investigate locomotion control and the role of the underlying central and peripheral components in the spinal cord. Many vertebrate swimmers have central pattern generators and local pressure-sensitive receptors that provide information about the surrounding fluid. However, it remains difficult to study experimentally how these sensors influence…

    Source: Science Robotics
    Categories: Future of Medicine, Latest Headlines
    Tweet Tweets with this article
    • Profile photo of SciRobotics
      SciRobotics

      A lamprey-inspired #robot replicated the slithering movement of lampreys and eels underwater by aligning an internal #neural circuit – akin to a lamprey’s spinal cord – with external sensors: https://t.co/8Q7cGzDnZb @EPFL_en, @KMRoBoTa https://t.co/QrXjalROVZ

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