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Mashup Score: 7
Background Poor immune function is associated with increased risk for a number of age-related diseases, however, little is known about the impact of early life trauma on immune function in late-life. Methods Using nationally representative data from the Health and Retirement Study (n = 5,823), we examined the association between experiencing parental/caregiver death or separation before age 16…
Source: journals.plos.orgCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 11Space travel can alter gene expression in white blood cells, weakening our immune system - 10 month(s) ago
Evidence is mounting that astronauts are more susceptible to infections while in space. For example, astronauts on board the International Space Station (ISS) commonly suffer from skin rashes, as well as respiratory and non-respiratory diseases. Astronauts are also known to shed more live virus particles; for example, the Epstein-Barr virus, varicella-zoster responsible for shingles,…
Source: medicalxpress.comCategories: General Medicine News, Latest HeadlinesTweet-
Space travel can alter #geneexpression in white blood cells, weakening our #immunesystem @frontiersin @frontiersin https://t.co/YP59wSbu3H
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Mashup Score: 6
In the quest to find the origin of the puzzling symptoms in four children, researchers from St. Anna Children’s Cancer Research Institute, the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences (ÖAW), and the Medical University of Vienna have discovered a completely new disease, linking disruptions of blood formation, the immune system, and inflammation. This…
Source: medicalxpress.comCategories: General Medicine News, Latest HeadlinesTweet-
Newly discovered genetic defect disrupts blood formation and #immunesystem @nejm https://t.co/4t6PLSdV2L
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Mashup Score: 3Lung cancer expert Dr. McGarry Houghton receives Satya and Rao Remala Family Endowed Chair - 10 month(s) ago
Fred Hutch’s Dr. McGarry Houghton, whose work explores the immune system’s role in cancer and lung cancer early detection, has been named the first recipient of the Satya and Rao Remala Family Endowed Chair.
Source: Fred HutchCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
McGarry Houghton, MD, a pulmonary physician-scientist whose work explores the role of the #immunesystem in cancer and #lungcancer #earlydetection, has been named the first recipient of the Satya and Rao Remala Family Endowed Chair at Fred Hutch. https://t.co/Q5UnCGF0uO
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Mashup Score: 5β-catenin drives butyrophilin-like molecule loss and γδ T-cell exclusion in colon cancer - 11 month(s) ago
Abstract. Intraepithelial lymphocytes (IELs) expressing γδ T-cell receptors (γδTCRs) play key roles in elimination of colon cancer. However, the precise mechanisms by which progressing cancer cells evade immunosurveillance by these innate T cells are unknown. Here, we investigated how loss of the Apc tumor suppressor in gut tissue could enable nascent cancer cells to escape immunosurveillance by…
Categories: General Medicine News, Latest HeadlinesTweet-
Researchers discover how bowel #cancer 'blinds' the #immunesystem https://t.co/wreuxzmyVg https://t.co/V5SshW8Q9T
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Mashup Score: 1Scientists discover how Golden staph hides and thrives in human cells using state-of-the-art research tool - 11 month(s) ago
Researchers have discovered how Golden staph, a common bug that can cause one of the most serious bacterial infections, hides inside human cells to avoid detection by the immune system.
Source: EurekAlert!Categories: General Medicine News, Latest HeadlinesTweet-
Researchers @TheDohertyInst discovered how Golden staph, a common bug that can cause one of the most serious #bacterialinfections, hides inside #human #cells to avoid detection by the #immunesystem #microbiology #discoveryresearch https://t.co/PIcE5wKchT
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Mashup Score: 12Mechanistic insights into the interactions between cancer drivers and the tumour immune microenvironment - Genome Medicine - 11 month(s) ago
Background The crosstalk between cancer and the tumour immune microenvironment (TIME) has attracted significant interest in the latest years because of its impact on cancer evolution and response to treatment. Despite this, cancer-specific tumour-TIME interactions and their mechanistic insights are still poorly understood. Methods Here, we compute the significant interactions occurring between…
Source: BioMed CentralCategories: General Medicine News, Latest HeadlinesTweet-
Uncovering #cancer-#immunesystem interactions could inform how patients respond to immunotherapy @thecrick https://t.co/Yqn6XdX0Hw https://t.co/aTw5RaW3KQ
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Mashup Score: 6Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome - 11 month(s) ago
This study describes an innate immune mechanism for sensing coronavirus and picornavirus infection by detecting the activity of virus-encoded proteases. Genetic variants among mammalian hosts affect which viruses can be sensed by this host ‘tripwire’ system, confirming its importance in the evolutionary arms race between viruses and the host immune response.
Source: journals.plos.orgCategories: General Medicine News, Latest HeadlinesTweet-
Researchers find an #immunesystem 'trip wire' that detects #COVID-19 @ucsandiego @PLOSBiology https://t.co/k34oVSf77M https://t.co/BoHIY2u5RF
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Mashup Score: 0The Immune System - 1 year(s) ago
Introduction Immuno-oncology is an evolving field of study on the role of the immune system in cancer initiation and growth. This introductory module describes the purpose of the human immune system, components of the immune system, and innate and adaptive immune responses. The immune system is the body’s biological defense system. The main purpose of the immune system is to identify self from…
Source: www.healio.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Get a refresh on the purpose of the human immune system, components of the immune system, and innate and adaptive immune responses with Clinical Guidance. https://t.co/8ay2GXl367 #ClinicalGuidance #ImmunoOncology #ImmuneSystem https://t.co/dkI3Ft9Fs4
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Mashup Score: 10
Immunotherapies have shown limited efficacy in patients with glioma. Here, based on an in vivo kinome knockout CRISPR screen, the authors show that checkpoint kinase 2 promotes CD8 T cell immune evasion and that its depletion or inhibition improve survival and response to PD1/PDL1 blockade in preclinical glioma models.
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet-
Study identifies enzyme that helps tumors evade the #immunesystem @northwesternu @NatureComms https://t.co/cl2jGawZTj https://t.co/r6j4HtQdzq
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Losing a parent early in life impacts a person's #immunesystem as they age, study finds @umich @PLOSONE https://t.co/Bq98E9w7Cj https://t.co/4fzZyljWak