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Mashup Score: 3Aspirin may have ‘direct role’ in augmenting the immune system to fight colorectal cancer - 4 day(s) ago
Whereas previous studies have shown aspirin use decreases incidence and mortality of colorectal cancer, researchers may now have insight into why this occurs, according to study results published in Cancer.Individuals who used aspirin had fewer nodal metastases and increased tumor-infiltrating lymphocyte penetration, and expressed more proteins to help the body ward off the disease in the
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Mashup Score: 0
The FDA approved nogapendekin alfa inbakicept-pmln plus Bacillus Calmette-Guerin for the treatment of certain patients with bladder cancer, according to a press release from the manufacturer.The indication applies to individuals with Bacillus Calmette-Guerin (BCG) unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ.
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Mashup Score: 0Novel blood test shows promising accuracy for detection of early-stage pancreatic cancer - 4 day(s) ago
A next-generation biomarker-based blood test demonstrated 98% specificity and 75% sensitivity in detecting stage I and II pancreatic ductal adenocarcinoma, according to a press release from the manufacturer.The test, which achieved both primary and secondary endpoints during a model-development study, is more accurate than CA19-9, the biomarker typically used to detect pancreatic cancer,
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Mashup Score: 0
Use of immune checkpoint inhibitors for pregnant women with cancer may be safer than previously thought, according to study results published in JAMA Network Open.Patients treated with immune checkpoint inhibitors (ICIs) did not experience significantly more pregnancy-related, fetal or neonatal adverse events compared with those who received other anticancer therapies.
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Mashup Score: 0
The addition of durvalumab to chemotherapy doubled 3-year survival among patients with advanced biliary tract cancers, according to data released by the agent’s manufacturer. Durvalumab (Imfinzi, AstraZeneca) is a human monoclonal antibody that binds to PD-L1. The agent is approved in the United States for treatment of locally advanced or metastatic biliary tract cancer. It also is
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Mashup Score: 2
The future of pediatric oncology should place a special emphasis on addressing socioeconomic difficulties that childhood cancer survivors face, according to study data published in JAMA Pediatrics.Researchers found childhood cancer survivors had higher odds of health-related unemployment, in addition to being less likely to complete higher levels of education, get married or become parents
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Mashup Score: 0
A 10-minute video designed to educate Black men on prostate cancer risks prompted 93% of viewers to report they intend to be screened in the future, according to study results presented at American Association for Cancer Research Annual Meeting.Nearly all watchers came away from the video understanding Black men had a higher risk for prostate cancer and the information had utility.
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Mashup Score: 0Next-generation PARP inhibitor shows clinical benefit in certain patients with breast cancer - 11 day(s) ago
Saruparib conferred clinically impactful treatment outcomes among adults with breast cancer who harbor certain genetic mutations, according to data presented at American Association for Cancer Research Annual Meeting. Researchers also reported a favorable safety profile for the investigational agent, along with a low dose reduction rate compared with certain approved [poly(ADP)-ribose polymerase
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Mashup Score: 3Patients with advanced cancer value ‘realistic care’ goals that avoid costly treatments - 11 day(s) ago
More than one-third of patients and one-fourth of patient caregivers favor focusing on symptom management of advanced cancers over life extension, according to study findings published in JAMA Network Open.The results also showed little difference in attitudes about the goals of care between patients and caregivers as those with cancer neared death.
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Mashup Score: 7
An investigational exosome-based liquid biopsy showed better than 90% accuracy for detecting early-stage pancreatic cancer among U.S.-based participants in a prospective multicenter study. When combined with a signature that identified the protein CA 19-9, a known tumor biomarker for pancreatic cancer, the novel liquid biopsy accurately detected 97% of stage I or stage II pancreatic ductal
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Individuals with colorectal cancer who used aspirin had fewer nodal metastases and increased tumor-infiltrating lymphocyte penetration, according to data in @JournalCancer. Healio spoke with a @UniPadova staff surgeon about the study. 🔗Read more https://t.co/nhMRgJFVll