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Mashup Score: 1How SARS-CoV-2 battles our immune system - 2 year(s) ago
Meet the protein arsenal wielded by the pandemic virus
Source: www.science.orgCategories: Infectious Disease, Latest HeadlinesTweet
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Mashup Score: 16
Summary:Tumor-specific cytotoxic T cells unleashed by the blockade of immune checkpoints have to overcome a hostile tumor microenvironment (TME). They start from very small numbers of T cells with tumor antigen specificity and, despite expansion, likely remain at a numerical disadvantage to the tumor cells they target. To overcome these obstacles, we propose that T cells need to change the TME to…
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Perspective: When #cancercells become the enablers of an antitumor #immuneresponse, by Toni Ribas, @nickhaining, and Ton Schumacher. https://t.co/RpN8er8avD @UCLAJCCC @ArsenalBio @NKI_nl https://t.co/3TyWqmyGS6
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Mashup Score: 12SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies - 2 year(s) ago
SARS-CoV-2 host-shutoff inhibits innate NK surveillance by suppressing activating ligands, however ADCC provides a potent NK stimulus that is mediated by antibodies targeting Nucleocapsid, ORF3a, and Membrane, with those targeting Spike being significantly weaker.
Source: eLifeCategories: General Medicine News, Latest HeadlinesTweet-
Scientists shed new light on how #SARS-CoV-2 evades #immuneresponse in early infection @elife https://t.co/ffzFIBISFf https://t.co/bkndW4dZJk
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Mashup Score: 0
Organ transplant recipients take life-long immunosuppressive drugs to prevent their bodies from mounting an immune response against the donated organ, yet a substantial number of them still reject the organs. A new study by researchers from the University of Chicago shows that transplant recipients also mount an immune response against commensal bacteria in the organ graft, adding to the immune…
Source: EurekAlert!Categories: General Medicine News, Latest HeadlinesTweet-
Bacteria in donor #organs may complicate #immuneresponse after transplantation @Uchicago https://t.co/XdtaK3CCIl
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Mashup Score: 7
Organ transplant recipients take life-long immunosuppressive drugs to prevent their bodies from mounting an immune response against the donated organ, yet a substantial number of them still reject the organs. A new study by researchers from the University of Chicago shows that transplant recipients also mount an immune response against commensal bacteria in the organ graft, adding to the immune…
Source: medicalxpress.comCategories: General Medicine News, Latest HeadlinesTweet-
#Bacteria in donor organs complicate #immuneresponse after transplantation @jclinicalinvest https://t.co/QlR8SeQmwN
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Mashup Score: 5
A study from the National Institutes of Health describes the immune response triggered by COVID-19 infection that damages the brain’s blood vessels and may lead to short- and long-term neurological symptoms. In a study published in Brain, researchers from the National Institute of Neurological Disorders and Stroke (NINDS) examined brain changes in nine people who died suddenly after contracting…
Source: medicalxpress.comCategories: General Medicine News, Latest HeadlinesTweet-
Small study reveals how #immuneresponse triggered by COVID-19 may damage the brain @NIHforHealth https://t.co/rEP6X9efP0
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Mashup Score: 1
Researchers running the University of Oxford-led Com-COV study have reported the results of a study assessing the immune response and reactogenicity of two-dose vaccine schedules when administered at four-week and 12-week intervals, using the Oxford-AstraZeneca or Pfizer-BioNTech vaccines.
Source: medicalxpress.comCategories: General Medicine News, Latest HeadlinesTweet-
Results of study assessing #immuneresponse of two-dose COVID-19 #vaccine schedules @UniofOxford @LancetRespirMed https://t.co/UiD0vPy1uZ
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Mashup Score: 0The timing of differentiation and potency of CD8 effector function is set by RNA binding proteins - Nature Communications - 2 year(s) ago
RNA binding proteins (RBP) have a function in T cell activation and differentiation. Here the authors show that in the absence of two RBPs, ZFP36 and ZFP36L1, T cells acquire more rapidly superior effector capabilities, showing a limiting function for RBP in T cell activation and differentiation.
Source: NatureCategories: Infectious Disease, Latest HeadlinesTweet-
RNA binding proteins help T cells pick their weapons before battle: ⚔️ Led by Dr. Martin Turner (@MartT_babraham), scientists at the @BabrahamInst have shown that two RBPs hold the key 🔑 to a stronger #ImmuneResponse to #influenza in mice. 🔗 https://t.co/SzKoLixUP3 https://t.co/nQKCbPqGbd
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Mashup Score: 6
A new study in breast cancer survivors has found that chemotherapy, while a critical part of breast cancer therapy, may also have some lasting dampening effects on natural immunity, but moderate fitness improvements can offer some protection against this effect.
Source: medicalxpress.comCategories: General Medicine News, Latest HeadlinesTweet-
Moderate exercise improves #immuneresponse in breast #cancer survivors @OhioState @brainbehavimm https://t.co/0u1Lug4mvf
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Mashup Score: 10
The global eradication of smallpox in the 1980s was achieved by intradermal vaccination with vaccinia virus. A study published in PLOS Pathogens by Evgeniya V. Shmeleva, Brian J. Ferguson and Geoffrey L. Smith at University of Cambridge, United Kingdom and colleagues shows that there is a large increase in skin bacteria and suggests that this may enhance the immune response.
Source: medicalxpress.comCategories: General Medicine News, Latest HeadlinesTweet-
#Skinbacteria may boost #immuneresponse of mice infected with smallpox vaccine @plos @PLOSPathogens https://t.co/3Bqs1mHcf7
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How does #SARSCoV2 battle our immune system? ⚔️ Over the past 3 years, investigators have begun to explore the virus's arsenal of proteins that neutralize the body's #ImmuneResponse. https://t.co/B17Zwwuh11