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Mashup Score: 16How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of immune cells - 16 day(s) ago
Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions. But previously, astonishingly little was known about how they exactly do that. A team of researchers …
Source: medicalxpress.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 17Activating a specific pathway in a subset of immune cells eradicates immunologically 'cold' tumors, study shows - 1 month(s) ago
A nanoparticle-based therapy developed by UT Southwestern Medical Center scientists stimulated an immune pathway that eradicated tumors in mouse models of various cancer types. Their findings, published …
Source: medicalxpress.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 13A distinct topology of BTN3A IgV and B30.2 domains controlled by juxtamembrane regions favors optimal human γδ T cell phosphoantigen sensing - 5 month(s) ago
Nature Communications – γδ T cells are known to recognize phosphoantigen in the context of butyrophilins (BTN), yet the molecular rules underlying this phenomenon are unclear. Here, the…
Source: www.nature.comCategories: General Medicine News, General NewsTweet
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Mashup Score: 15
The intestinal epithelium has a high turnover rate and constantly renews itself through proliferation of intestinal crypt cells, which depends on insu…
Source: www.sciencedirect.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 11The miR-23-27-24 clusters drive lipid-associated macrophage proliferation in obese adipose tissue - 8 month(s) ago
Identifying molecular circuits that control adipose tissue macrophage (ATM) function is necessary to understand how ATMs contribute to tissue homeosta…
Source: www.sciencedirect.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0
An abstract is unavailable.
Source: journals.lww.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 8Gut-licensed β7+ CD4+ T cells contribute to progressive retinal ganglion cell damage in glaucoma - 9 month(s) ago
Gut-licensed β7-expressing CD4+ T cells can infiltrate the retina by inducing MAdCAM-1 expression and contribute to glaucoma pathogenesis.
Source: www.science.orgCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 11Single-cell microglial transcriptomics during demyelination defines a microglial state required for lytic carcass clearance - Molecular Neurodegeneration - 11 month(s) ago
Background Microglia regulate the response to injury and disease in the brain and spinal cord. In white matter diseases microglia may cause demyelination. However, how microglia respond and regulate demyelination is not fully understood. Methods To understand how microglia respond during demyelination, we fed mice cuprizone—a potent demyelinating agent—and assessed the dynamics of genetically…
Source: BioMed CentralCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 15Nucleocapsid-specific T cell responses associate with control of SARS-CoV-2 in the upper airways before seroconversion - Nature Communications - 11 month(s) ago
Authors carry out an immunogenetic and virologic analysis of nasopharyngeal and peripheral blood samples, finding that early nucleocapsid-specific T cell responses associate with control of SARS-CoV-2 in the upper airways and reduced systemic inflammation before seroconversion.
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 8
Understanding the ways our immune response changes as we age holds the key to designing better vaccines and boosting protection for people most at risk. Research published by Dr. Michelle Linterman and her group today in Nature Immunology has explained that the organization of the germinal center, which is vital to the generation of longer-lived protection following vaccination, is altered in…
Source: medicalxpress.comCategories: General Medicine News, Latest HeadlinesTweet
How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of #immuneCells @nature https://t.co/0PgGFOyPFI