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Mashup Score: 1Targeted use of ultrasound technology can lead to significant changes in brain function - 8 month(s) ago
The targeted use of ultrasound technology can bring about significant changes in brain function that could pave the way towards treatment of conditions such as depression, addiction, or anxiety, a new study suggests.
Source: www.news-medical.netCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 1E2730, an uncompetitive GABA transporter‐1 inhibitor, suppresses epileptic seizures in a rat model of chronic mesial temporal lobe epilepsy - 9 month(s) ago
Objective More than one-third of mesial temporal lobe epilepsy (MTLE) patients are resistant to current anti-seizure medications (ASMs), while half experience mild-to-moderate adverse effects of ASM…
Source: onlinelibrary.wiley.comCategories: Latest Headlines, NeurologyTweet-
E2730, an uncompetitive GABA transporter-1 inhibitor, suppresses epileptic #seizures in a rat model of chronic mesial temporal lobe #epilepsy https://t.co/VqFk0fn7ly #GABA #GABAtransporter #temporallobeepilepsy #pharmacokinetics #vEEG #ILAE @IlaeWeb @epilepsiajourn @WileyNeuro https://t.co/B6Vsgy9CDe
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Mashup Score: 0How ketamine affects three key regions of brain - 11 month(s) ago
It’s a powerful antidepressant, but science needs more answers on out-of-body experiences and other “dissociative effects,” says the first author Fangyun Tian.
Source: Harvard GazetteCategories: Healthcare Professionals, Latest HeadlinesTweet-
Nice summary of a complex paper: How #ketamine affects three key regions of #brain https://t.co/31Le2GLECa via @Harvard #NMDA #HCN1 #GABA #Depression #MDD #anesthesia #EEG Characterizing brain dynamics during ketamine-induced #dissociation and subsequent interactions with… https://t.co/cEy8GN55fF https://t.co/0xg5oSFEae
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Mashup Score: 7
Based on preclinical studies, gamma aminobutyric acid (GABA) and immunization for the enzyme that produces GABA glutamate decarboxylase (GAD) could be a potential therapy for type 1 diabetes. Here the authors report that in a placebo-controlled, double blind trial in children with new onset type 1 diabetes oral GABA plus GAD did not preserve beta-cell function measured as fasting/meal-stimulated…
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet-
Type 1 diabetes: First clinical trial of #GABA/GAD in newly diagnosed, very young children @NatureComms https://t.co/8ibfSCcuHk https://t.co/3zUzDx3HhI
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Mashup Score: 0
Infection with SARS-CoV-2, the causative agent of the COVID-19 pandemic, originated in China and quickly spread across the globe. Despite tremendous economic and healthcare devastation, research on this virus has contributed to a better understanding of numerous molecular pathways, including those involving γ-aminobutyric acid (GABA), that will positively impact medical science, including…
Source: MDPICategories: Healthcare Professionals, Latest HeadlinesTweet-
Neuronal and Non-Neuronal #GABA in #COVID19: Relevance for #Psychiatry https://t.co/tPgTz4vInk
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Mashup Score: 17Filamin A organizes γ‑aminobutyric acid type B receptors at the plasma membrane - Nature Communications - 1 year(s) ago
GABAB receptors mediate the effects of the main inhibitory neurotransmitter in the brain. Here, authors identify the cytoskeletal protein filamin A as a key player that controls the exact location and function of GABAB receptors at the cell surface.
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet-
Protein 'anchors' found to play key role in neurotransmitter #GABA action @NatureComms https://t.co/YSCg9BAdIh https://t.co/xi0HCnfzK4
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Mashup Score: 0
Research explores how new information is consolidated across the sleep-wake cycle.
Categories: Healthcare Professionals, Latest HeadlinesTweet-
NIH study in mice provides insight into how #brain activity is fine-tuned https://t.co/Ehf8if0Z2w “This is the first study to try to understand how #sleep and #wakefulness regulate inhibitory #synapses.” #GABA
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Mashup Score: 0
An international team of researchers, led by scientists at UC San Diego, report that a gene therapy that inhibits targeted nerve cell signaling effectively reduced neuropathic pain with no detectable side effects in mice with spinal cord or peripheral nerve injuries.
Source: EurekAlert!Categories: Healthcare Professionals, Latest HeadlinesTweet-
#Genetherapy shows promise in treating #neuropathy from #spinalcord injuries https://t.co/lnkKDgJHn7 Precision #spinal gene delivery-induced functional switch in nociceptive neurons reverses #neuropathicpain. #dorsalhorm #GABA #sciatica #neurotransmitters https://t.co/jC9lBqyO1G https://t.co/hFElSrVu0f
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Mashup Score: 19GABA released by B-cells blunts the immune response to tumors - 2 year(s) ago
A group of scientists led by researchers from the RIKEN Center for Integrative Medical Sciences have discovered that B-cells, a type of immune cell, secrete the neurotransmitter GABA, and also found that the GABA secreted by the B-cells promoted the emergence of anti-inflammatory macrophages, blunting the body’s cytotoxic T-cell-based response to tumors. According to the authors, this work,…
Source: medicalxpress.comCategories: General Medicine News, Latest HeadlinesTweet-
#GABA released by B-cells blunts the #immuneresponse to tumors @riken_en @nature https://t.co/IOcc26zHxz
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Mashup Score: 14The GABAB receptor mediates neuroprotection by coupling to G13 - 3 year(s) ago
Distinct G protein–mediated pathways mediate neuroprotective GABAB receptor signaling.
Source: Science SignalingCategories: Future of Medicine, Latest HeadlinesTweet-
The neurotransmitter #GABA protects neurons through multiple synergistic pathways that depend on distinct #Gproteins, according to a new study in @scisignal. https://t.co/UuFg1xhEyk https://t.co/nI4HM0vn3H
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Targeted use of #ultrasound technology can lead to significant changes in #brain function https://t.co/FaFXmU7qBE #GABA Transcranial #focusedultrasound-mediated neurochemical and functional connectivity changes in deep cortical regions in humans @NatureComms… https://t.co/hqzrd0wErC