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Mashup Score: 7Science Signaling | AAAS - 12 month(s) ago
Science Signaling publishes studies that provide mechanistic insights into physiology and disease, identify new therapeutic targets, and characterize drugs.
Source: Science SignalingCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 21Science Signaling | AAAS - 12 month(s) ago
Science Signaling publishes studies that provide mechanistic insights into physiology and disease, identify new therapeutic targets, and characterize drugs.
Source: Science SignalingCategories: Expert Picks, Latest HeadlinesTweet-
This important work certainly warrants the cover Legend here https://t.co/T9JJkeNVNy https://t.co/RL7Gphwaq0
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Mashup Score: 11Distinct PEAK3 interactors and outputs expand the signaling potential of the PEAK pseudokinase family - 2 year(s) ago
The pseudokinase scaffold PEAK3 interacts with diverse components involved in growth factor signaling.
Source: Science SignalingCategories: Future of Medicine, Latest HeadlinesTweet-
Scientists have discovered new roles for the #pseudokinase PEAK3 in growth factor signaling and cell invasiveness—supporting the idea that PEAK3 could be a target for new treatments for #cancer. https://t.co/9jlahrek6L @SciSignal https://t.co/UzvH1oNg1n
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Mashup Score: 27Distinct PEAK3 interactors and outputs expand the signaling potential of the PEAK pseudokinase family - 2 year(s) ago
The pseudokinase scaffold PEAK3 interacts with diverse components involved in growth factor signaling.
Source: Science SignalingCategories: Future of Medicine, Latest HeadlinesTweet-
Scientists have discovered new roles for the #pseudokinase PEAK3 in growth factor signaling and cell invasiveness—supporting the idea that PEAK3 could be a target for new treatments for #cancer. https://t.co/9jlahrek6L @SciSignal https://t.co/gK83yyddR3
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Mashup Score: 2Arenaviral infection causes bleeding in mice due to reduced serotonin release from platelets - 2 year(s) ago
Defective platelets generated from megakaryocytes exposed to arenaviral infection–induced interferon increase bleeding risk.
Source: Science SignalingCategories: Future of Medicine, Latest HeadlinesTweet-
New experiments in mice in @SciSignal clarify how infections with an #arenavirus can cause dangerous bleeding, and hint that platelet transfusions could help stanch hemorrhage in infected patients. https://t.co/0SH1qHExAa #InfectiousDisease https://t.co/Y7GNnN1DlJ
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Mashup Score: 19Phenotypic variability, not noise, accounts for most of the cell-to-cell heterogeneity in IFN-γ and oncostatin M signaling responses - 2 year(s) ago
Variability in the cellular response to cytokines is due more to molecular phenotype than to noise.
Source: Science SignalingCategories: Future of Medicine, Latest HeadlinesTweet-
Why do cells vary in their signaling responses? Using a binucleated cell system, a new study in @SciSignal finds that molecular variability across cells—and not random biochemical “noise”—may shape variations in signaling outcomes. #SystemsBiology https://t.co/EQJgRh7E1e https://t.co/VqzD7SkspS
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Mashup Score: 12Arenaviral infection causes bleeding in mice due to reduced serotonin release from platelets - 2 year(s) ago
Defective platelets generated from megakaryocytes exposed to arenaviral infection–induced interferon increase bleeding risk.
Source: Science SignalingCategories: Future of Medicine, Latest HeadlinesTweet-
New experiments in mice in @SciSignal clarify how infections with an #arenavirus can cause dangerous bleeding, and hint that platelet transfusions could help stanch hemorrhage in infected patients. https://t.co/0SH1qHExAa #InfectiousDisease https://t.co/DI6cmRC7oc
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Mashup Score: 42Phenotypic variability, not noise, accounts for most of the cell-to-cell heterogeneity in IFN-γ and oncostatin M signaling responses - 2 year(s) ago
Variability in the cellular response to cytokines is due more to molecular phenotype than to noise.
Source: Science SignalingCategories: Future of Medicine, Latest HeadlinesTweet-
Why do cells vary in their signaling responses? Using a binucleated cell system, a new study in @SciSignal finds that molecular variability across cells—and not random biochemical “noise”—may shape variations in signaling outcomes. #SystemsBiology https://t.co/EQJgRgQ2CE https://t.co/MwW9X3CCgN
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Mashup Score: 64Themis is indispensable for IL-2 and IL-15 signaling in T cells - 2 year(s) ago
The T cell–specific adaptor protein Themis is necessary for cytokine-induced T cell proliferation.
Source: Science SignalingCategories: Future of Medicine, Latest HeadlinesTweet-
A new study sheds light on the many roles of the critical protein Themis in #Tcell biology—and provides clues that could guide the manipulation of T cells in #CellTherapy and other clinical applications. https://t.co/RjSmd579v6 @SciSignal https://t.co/MdAY81LFka
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Mashup Score: 0A noninvasive iRFP713 p53 reporter reveals dynamic p53 activity in response to irradiation and liver regeneration in vivo - 2 year(s) ago
A reporter allows noninvasive, longitudinal imaging of p53 activation in mice.
Source: Science SignalingCategories: Hem/Oncs, Latest HeadlinesTweet-
A noninvasive iRFP713 p53 reporter reveals dynamic p53 activity in response to irradiation and liver regeneration in vivo https://t.co/9yvjJqrENb
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RT @EricTopol: This important work certainly warrants the cover Legend here https://t.co/T9JJkeNVNy https://t.co/RL7Gphwaq0