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Mashup Score: 10A noninvasive iRFP713 p53 reporter reveals dynamic p53 activity in response to irradiation and liver regeneration in vivo - 2 year(s) ago
A reporter allows noninvasive, longitudinal imaging of p53 activation in mice.
Source: Science SignalingCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 30Themis is indispensable for IL-2 and IL-15 signaling in T cells - 2 year(s) ago
The T cell–specific adaptor protein Themis is necessary for cytokine-induced T cell proliferation.
Source: Science SignalingCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 10Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids - 2 year(s) ago
Movement of the N-terminal domain determines whether lipids obstruct the pore of the channel pannexin-1.
Source: Science SignalingCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 27A noninvasive iRFP713 p53 reporter reveals dynamic p53 activity in response to irradiation and liver regeneration in vivo - 2 year(s) ago
A reporter allows noninvasive, longitudinal imaging of p53 activation in mice.
Source: Science SignalingCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 17Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids - 2 year(s) ago
Movement of the N-terminal domain determines whether lipids obstruct the pore of the channel pannexin-1.
Source: Science SignalingCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 1
Imaging the SH2 domains of signaling proteins by superresolution microscopy reveals T cell receptor signaling events.
Source: Science SignalingCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 48
Imaging the SH2 domains of signaling proteins by superresolution microscopy reveals T cell receptor signaling events.
Source: Science SignalingCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 42Phosphorylation-dependent positive feedback on the oxytocin receptor through the kinase PKD1 contributes to long-term social memory - 2 year(s) ago
A positive feedback loop that stimulates oxytocin receptor activity helps rodents remember each other.
Source: Science SignalingCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 77Phosphorylation-dependent positive feedback on the oxytocin receptor through the kinase PKD1 contributes to long-term social memory - 2 year(s) ago
A positive feedback loop that stimulates oxytocin receptor activity helps rodents remember each other.
Source: Science SignalingCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 16The adaptor SH2B1 and the phosphatase PTP4A1 regulate the phosphorylation of cytohesin-2 in myelinating Schwann cells in mice - 2 year(s) ago
Opposing regulation of the phosphorylation state of cytohesin-2 determines the extent of peripheral neuron myelination.
Source: Science SignalingCategories: Future of Medicine, Latest HeadlinesTweet
Researchers have generated a fluorescent reporter that can noninvasively visualize the dynamics of the #p53 protein in live mice—offering a tool to elucidate this tumor supressor’s roles in both normal physiology and disease. https://t.co/AMeRCSdf0S @SciSignal https://t.co/pQ5UYUXcwE