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Mashup Score: 2RHOJ controls EMT-associated resistance to chemotherapy - Nature - 1 year(s) ago
RHOJ regulates epithelial-to-mesenchymal-transition-associated resistance to chemotherapy by enhancing the response to replicative stress and activating the DNA damage response, enabling tumour cells to rapidly repair DNA lesions induced by chemotherapy.
Source: NatureCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0
How did first responders and firefighters navigate the COVID-19 pandemic and its aftermath? Two firefighters/EMTs describe what that time was like for them.
Source: Infection Control TodayCategories: Infectious Disease, Latest HeadlinesTweet
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Mashup Score: 2The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression - Oncogene - 2 year(s) ago
The epithelial to mesenchymal transition (EMT), a process that is aberrantly activated in cancer and facilitates metastasis to distant organs, requires coordinated transcriptional and post-transcriptional control of gene expression. The tumor-suppressive RNA binding protein, hnRNP-E1, regulates splicing and translation of EMT-associated transcripts and it is thought that it plays a major role in…
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 2
Your access to the latest cardiovascular news, science, tools and resources.
Source: www.escardio.orgCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 1
Your access to the latest cardiovascular news, science, tools and resources.
Source: www.escardio.orgCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 2Compassionate Response - 2 year(s) ago
A free training experience designed for agencies partnering with First Responders
Source: ZERO TO THREECategories: Latest Headlines, PediatricsTweet
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Mashup Score: 3
The epithelial-to-mesenchymal transition (EMT) has been recognized as a driving force for tumor progression in breast cancer. Recently, our group identified the RNA Binding Motif Single Stranded Interacting Protein 3 (RBMS3) to be significantly associated with an EMT transcriptional program in breast cancer. Additional expression profiling demonstrated that RBMS3 was consistently upregulated by…
Source: OncogeneCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Calibrate scores $100M following company's one year anniversary and more digital health fundings - 3 year(s) ago
Also: Better Therapeutics scored a $50 million loan facility, DiA Imaging Analysis raised $14 million and SCAN Group invested in MedArrive.
Source: MobiHealthNewsCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 3Wolters Kluwer Health - 3 year(s) ago
JavaScript Error JavaScript has been disabled on your browser. You must enable it to continue. Here’s how to enable JavaScript in the following browsers: Internet Explorer From the Tools menu, select Options Click the Content tab Select Enable JavaScript Firefox From the Tools…
Source: lww.comCategories: Latest Headlines, NeurologyTweet-
For #MondayMotivation: 5 young people on track for careers in #neurology: facing paralysis, #COVID19 floors, an #EMT truck, the next great big idea, and more. Read their stories here. https://t.co/n5OnX5g1yI @RoyaEdalatpour @GabrieladePaz5 #neurologyproud @AANMember #neurotwitter https://t.co/1h374eRJVl
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Mashup Score: 2Single-Cell RNA Sequencing Uncovers Paracrine Functions of the Epicardial-Derived Cells in Arrhythmogenic Cardiomyopathy - 3 year(s) ago
Background: Arrhythmogenic cardiomyopathy (ACM) manifests with sudden death, arrhythmias, heart failure, apoptosis, and myocardial fibro-adipogenesis. The phenotype typically starts at the epicardium
Source: CirculationCategories: Cardiology News and Journals, Latest HeadlinesTweet-
In mouse model of #arrhythmogenicCMP, epicardial-derived cardiac fibroblasts & epithelial cells express paracrine factors (ie, TGFβ1, FGFs) which mediate #EMT & contribute to pathogenesis of myocardial fibrosis, apoptosis, arrhythmias & cardiac dysfunction https://t.co/htwtC7tMvx https://t.co/Oq6pQ1WdIu
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EMT has been associated with #resistance to therapy in #cancer cells. RHOJ, a small GTPase expressed in #EMT cancer cells, controls resistance to therapy by enhancing the response to replicative stress and activating the DNA-damage response. https://t.co/7GQ3XspY8e https://t.co/gAUJvQQPLO