• Mashup Score: 2

    Pericardial disease in the developing world is dominated primarily by effusive and constrictive syndromes and contributes to the acute and chronic heart failure burden in many regions. The confluence of geography (location in the tropics), a significant burden of diseases of poverty and neglect, and a significant contribution of communicable diseases to the general burden of disease is reflected in the wide etiological spectrum of causes of pericardial disease. The prevalence of Mycobacterium tuberculosis in particular, is high throughout much of the developing world where it is the most frequent and important cause of pericarditis and is associated with significant morbidity and mortality.

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    • RT @CJCJournals: *** New #CJC Review *** #Pericardial #disease in the developing world 👉 https://t.co/o3x0Sxvt1f https://t.co/p9tB4VSv4n

  • Mashup Score: 1

    Nature Genetics – A modified framework leveraging a protein language model (ESM1b) is used to predict all possible 450 million missense variant effects in the human genome and shows potential for…

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    • THIS ROCKS: #Genome-wide prediction of #disease variant effects with a deep protein language model https://t.co/X6IwVMRHvv #Genetics #Genomics #ClinVar #HGMD Advancing #variant effect prediction using protein language models https://t.co/KuI085HUJ4 #pathogenic #SNV/#SNP… https://t.co/lT0TnZv0EK https://t.co/cwI5AWqxqb

  • Mashup Score: 4

    Background: Cardiovascular disease (CVD) mortality is persistently higher in the Black population than in other racial and ethnic groups in the United States. Objective: To examine the degree to which social, behavioral, and metabolic risk factors are associated with CVD mortality and the extent to which racial differences in CVD mortality persist after these factors are accounted for. Design: Prospective cohort study. Setting: NHANES (National Health and Nutrition Examination Survey) 1999 to 2018. Participants: A nationally representative sample of 50 808 persons aged 20 years or older. Measurements: Data on social, behavioral, and metabolic factors were collected in each NHANES survey using standard methods. Deaths from CVD were ascertained from linkage to the National Death Index with follow-up through 2019. Results: Over an average of 9.4 years of follow-up, 2589 CVD deaths were confirmed. The age- and sex-standardized rates of CVD mortality were 484.7 deaths per 100 000 person-yea

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    • Why are Black adults at greater risk of death from heart #disease? Study blames #socialfactors @AnnalsofIM https://t.co/L5bv61wseR https://t.co/f2OSF36DdP

  • Mashup Score: 0

    July 11, 2023 — The U.S. Food and Drug Administration (FDA) is informing healthcare providers about updated information associated with paclitaxel-coated devices used to treat peripheral arterial disease (PAD). Based on the FDA’s review of the totality of the available data and analyses, it has determined that the data does not support an excess mortality risk for paclitaxel-coated devices. The…

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    • @DAICeditor @FDADeviceInfo The U.S. Food and Drug Administration (#FDA) has issued a Letter to #HealthCare Providers about updated information associated with #paclitaxel-coated devices used to treat #peripheral #arterial #disease (#PAD): https://t.co/1owQZPwQD0