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Mashup Score: 9The Association of Plasma and Urine Uromodulin With Cardiovascular Disease in Persons With Hypertension and CKD - 22 day(s) ago
Uromodulin (UMOD) is a protein synthesized exclusively by tubular epithelial cells in the kidney. Higher urinary UMOD levels appear to reflect kidney tubule functional mass based on their direct association with kidney size, indices of tubular function, and lower risk of kidney disease progression.1 Higher UMOD concentrations in both the blood and urine have each been associated with lower rates of cardiovascular disease (CVD), but largely in separate cohorts.2,3 Owing to degradation and aggregation during storage,4 as well as changes in concentration from hydration,5 there are practical challenges to using urine UMOD measurements.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 2A Framework for Considering the Value of Race and Ethnicity in Estimating Disease Risk | Annals of Internal Medicine - 27 day(s) ago
Background: Accounting for race and ethnicity in estimating disease risk may improve the accuracy of predictions but may also encourage a racialized view of medicine. Objective: To present a decision analytic framework for considering the potential benefits of race-aware over race-unaware risk predictions, using cardiovascular disease, breast cancer, and lung cancer as case studies. Design: Cross-sectional study. Setting: NHANES (National Health and Nutrition Examination Survey), 2011 to 2018, and NLST (National Lung Screening Trial), 2002 to 2004. Patients: U.S. adults. Measurements: Starting with risk predictions from clinically recommended race-aware models, the researchers generated race-unaware predictions via statistical marginalization. They then estimated the utility gains of the race-aware over the race-unaware models, based on a simple utility function that assumes constant costs of screening and constant benefits of disease detection. Results: The race-unaware predictions we
Source: www.acpjournals.orgCategories: General Medicine News, General Journals & SocietTweet-
A new @AnnalsofIM paper presents a decision analytic framework for considering the potential benefits of race-aware over race-unaware risk predictions, using #CVD, breast cancer, and lung cancer as case studies. https://t.co/bpgM4P8CBH https://t.co/9uAApAaRUl
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Mashup Score: 24The Association of Plasma and Urine Uromodulin With Cardiovascular Disease in Persons With Hypertension and CKD - 3 month(s) ago
Uromodulin (UMOD) is a protein synthesized exclusively by tubular epithelial cells in the kidney. Higher urinary UMOD levels appear to reflect kidney tubule functional mass based on their direct association with kidney size, indices of tubular function, and lower risk of kidney disease progression.1 Higher UMOD concentrations in both the blood and urine have each been associated with lower rates of cardiovascular disease (CVD), but largely in separate cohorts.2,3 Owing to degradation and aggregation during storage,4 as well as changes in concentration from hydration,5 there are practical challenges to using urine UMOD measurements.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet-
The Association of Plasma and Urine Uromodulin With Cardiovascular Disease in Persons With Hypertension and CKD https://t.co/jFsFQMRY6s (FREE) @j_ikeme @pranavgarimella @estrella_khrc @shlipak_khrc @UCSFNephrology @KHRC_research #CVD https://t.co/CK9gdca9UY
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Mashup Score: 0ESC President, Prof Weidinger: “We need a common cardiac health plan to combat this burden” - 6 month(s) ago
Your access to the latest cardiovascular news, science, tools and resources.
Source: www.escardio.orgCategories: General Medicine News, CardiologistsTweet-
Professor Weidinger's successful two-year tenure as @ESC_President will conclude in September. Under the leadership of the Austrian cardiologist, the ESC has made notable strides in putting cardiovascular disease on the European political agenda. https://t.co/v9GMS2WO5s #CVD https://t.co/Fa3rmiCQqu
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Mashup Score: 55
Background: There is little consensus on using statins for primary prevention of cardiovascular diseases (CVDs) and all-cause mortality in adults aged 75 years or older due to the underrepresentation of this population in randomized controlled trials. Objective: To investigate the benefits and risks of using statins for primary prevention in old (aged 75 to 84 years) and very old (aged ≥85 years) adults. Design: Sequential target trial emulation comparing matched cohorts initiating versus not initiating statin therapy. Setting: Territory-wide public electronic medical records in Hong Kong. Participants: Persons aged 75 years or older who met indications for statin initiation from January 2008 to December 2015 were included. Participants with preexisting diagnosed CVDs at baseline, such as coronary heart disease (CHD), were excluded from the analysis. Among 69 981 eligible persons aged 75 to 84 years and 14 555 persons aged 85 years or older, 41 884 and 9457 had history of CHD equivalen
Source: www.acpjournals.orgCategories: General Medicine News, CardiologistsTweet-
Important new study in @AnnalsofIM showing safety & significant benefit of statins for primary #CVD prevention of stroke, MI & mortality in adults over 75 yo, even 85 yo+: https://t.co/CgeDl4JOPY https://t.co/wdTYcyjiEt
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Mashup Score: 0
Death rate vs urban areas continues to widen for cancer, heart disease, lung disease, and stroke
Source: www.medpagetoday.comCategories: General Medicine News, Cardiology News and JournTweet-
Rural Americans have higher rates 📈 of preventable premature mortality from the 5️⃣ leading causes of death than those living in urban areas, according to the CDC. More from @medpagetoday: https://t.co/UCid9tFfOV #CVD
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Mashup Score: 0
Death rate vs urban areas continues to widen for cancer, heart disease, lung disease, and stroke
Source: www.medpagetoday.comCategories: General Medicine News, Cardiology News and JournTweet-
Rural Americans have higher rates 📈 of preventable premature mortality from the 5️⃣ leading causes of death than those living in urban areas, according to the CDC. More from @medpagetoday: https://t.co/UCid9tFfOV #CVD
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Mashup Score: 8
AbstractAims. To examine the impact of population screening–generated events on quality of life: invitation, positive test result, initiation of preventive medi
Source: academic.oup.comCategories: General Medicine News, CardiologistsTweet-
impact of population screening for #CVD on quality of life https://t.co/AnA2UzeNSH
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Mashup Score: 7Women & CVD | World Heart Federation - 10 month(s) ago
The most common heart attack symptom, in both men and women, is some type of chest pain, pressure or discomfort. But chest pain is not always the most noticeable symptom, especially in women, who are more likely to experience it as pressure or tightness in the chest. They may even have no chest pain at […]
Source: world-heart-federation.orgCategories: General Medicine News, CardiologistsTweet-
Cardiovascular disease is NOT a man's disease. #CVD is responsible for 35% of deaths in women each year – more than ALL cancers combined. Yet, CVD in women continues to be under-diagnosed and under-treated. Visit @worldheartfed's website to learn more. https://t.co/DdyuNk9Drp
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Mashup Score: 2
Six biomarkers were associated with baseline and treatment-associated changes in arterial inflammation in patients with rheumatoid arthritis and could be used to predict CVD risk in that population, researchers reported.“Cardiovascular disease is more common in people with rheumatoid arthritis (RA) than the general population. However, our current risk models don’t work as well in RA
Source: www.healio.comCategories: General Medicine News, General HCPsTweet-
Six biomarkers could predict #CVD risk in patients with rheumatoid arthritis https://t.co/BVE8JYJ0GG
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The Association of Plasma and Urine Uromodulin With Cardiovascular Disease in Persons With Hypertension and CKD https://t.co/9fN56pmHrS (FREE) @j_ikeme @pranavgarimella @estrella_khrc @shlipak_khrc @UCSFNephrology @KHRC_research #CVD https://t.co/736izBsJqO