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Mashup Score: 1
This cohort study assesses changes in perinatal care, causes of preterm delivery, and rates of preterm delivery before and during the COVID-19 pandemic in Hesse, Germany.
Source: jamanetwork.comCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 2Can Marijuana Help Anxiety and Depression? - 5 hour(s) ago
You may have heard that marijuana can help ease your anxious or depressive symptoms. Here’s what we know about the effects of cannabis on mental health conditions like anxiety and depression.
Source: health.clevelandclinic.orgCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 1Impact of Value-Based Care in Oncology: Insights from COA 2024 - 10 hour(s) ago
Lalan Wilfong, MD, discusses the road to value-based care and payment reform in cancer care.
Source: www.pharmacytimes.comCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 5Unraveling the phenotypic states of human innate-like T cells: Comparative insights with conventional T cells and mouse models - 10 hour(s) ago
Our study presents a comprehensive atlas of human innate T (Tinn) cells in the thymus and blood, highlighting their blended type 1 and type 17 transcriptional profiles. Loh et al. use single-cell RNA sequencing and flow cytometry to reveal species-specific distinctions and potential divergent developmental pathways of Tinn compared to conventional T cells.
Source: www.cell.comCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 17Helen Salisbury: Resisting the temptation to offer advice - 11 hour(s) ago
When people consult their GP they often arrive with a clearly defined medical problem—a pain, a lump, breathlessness, a rash—and what they’re asking for is a diagnosis, treatment, and, if necessary, a referral. However, the solution to a problem isn’t always obvious or simple: a patient may present with back pain and insomnia, but further discussion may reveal relationship problems, stresses at work, or self-medication with alcohol in an attempt to deal with isolation and low mood. When patients come asking for help because they can no longer cope alone, it’s not easy to disentangle …
Source: www.bmj.comCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 10Deep learning meets histones at the replication fork - 11 hour(s) ago
Epigenetic inheritance of heterochromatin requires transfer of parental H3-H4 tetramers to both daughter duplexes during replication. Three recent papers exploit yeast genetics coupled to inheritance assays and AlphaFold2-multimer predictions coupled to biochemistry to reveal that a replisome component (Mrc1/CLASPIN) is an H3-H4 tetramer chaperone important for parental histone transfer to daughters.
Source: www.cell.comCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 9Does Absence of Pleocytosis in Cerebrospinal Fluid Exclude an Infectious Cause of Encephalitis? - 11 hour(s) ago
Diagnosing encephalitis can be difficult, but for viral causes with specific treatments — most commonly herpes simplex virus (HSV) — early initiation
Source: www.jwatch.orgCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 0New Hope for Rare but Challenging HER2 Mutations in NSCLC - 11 hour(s) ago
Data presented in the second Presidential Symposium at the 2024 World Conference on Lung Cancer showed encouraging responses to novel agents among patients with HER2-mutated non–small cell lung cancer (NSCLC).
Source: www.ajmc.comCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 0
The appropriateness of hospitalization for nursing home (NH) residents is still up for debate, with determining factors including timeliness, available treatmen…
Source: journals.sagepub.comCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 1Developments and Controversies in Invasive Diagnosis of Coronary Microvascular Dysfunction in Angina With Nonobstructive Coronary Arteries - 11 hour(s) ago
Approximately half of all coronary angiograms performed for angina do not show obstructive coronary artery disease, and many of these patients have coronary microvascular dysfunction (CMD). Invasive testing for CMD has increased with the advent and wider availability of thermodilution systems. We review CMD pathophysiology and invasive diagnostic testing using the Doppler and thermodilution systems. We report the results of a PubMed search of invasive microvascular testing and discuss limitations of current diagnostic algorithms in the diagnosis of CMD, including controversies regarding the optimal cutoff value for abnormal coronary flow reserve, use of microvascular resistance indices, and options for increasing sensitivity of testing.
Source: www.mayoclinicproceedings.orgCategories: General Medicine News, General Journals & SocietTweet
In this population-based cohort study on the #COVID19 pandemic and preterm birth rates, the duration of exposure to mitigation measures during pregnancy was associated with accelerated reductions in preterm births. https://t.co/f0SxZCA1ZY