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Mashup Score: 0
October 3, 2023 — A discovery of a mutation in the gene ACTA2 has given researchers, led by Dianna Milewicz, MD, PhD, with UTHealth Houston, insight into understanding the cause of a rare and progressive problem with arteries in the brain and a cause of strokes in young children, called moyamoya disease. The findings were published today in Nature Cardiovascular Research. Moyamoya disease is a condition where the arteries going through the neck and into the brain become blocked right when the arteries enter the brain. Moyamoya disease can lead to strokes and seizures. Children only a few months old can suffer a stroke due to the disease. Current treatments are limited to medications to reduce the risk of stroke and surgery to open or bypass blocked arteries. “This disease is one of the major causes of stroke in children and nobody knows why this happens or why these arteries get clogged,” said Milewicz, senior author of the study and professor and director of the Division of Medical
Source: www.dicardiology.comCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 8
These findings provide evidence that continuous glucose monitoring can reduce severe hypoglycaemia and ketoacidosis risk in young people with type 1 diabetes on insulin therapy. Continuous glucose monitoring metrics might help to identify those at risk for acute diabetes complications.
Source: www.thelancet.comCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 1ISPAD Clinical Practice Consensus Guidelines 2022 - International Society for Pediatric and Adolescent Diabetes - 7 month(s) ago
ISPAD in the only international society focusing on all types of diabetes in the worldwide population under 25. Help us in the global fight against diabetes in the young.
Source: www.ispad.orgCategories: Latest Headlines, PediatricsTweet
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Mashup Score: 1Whole Systems Approach to School-Based Physical Activity - Dr Andrew Daly-Smith (Pt1) - 7 month(s) ago
Dr Andy Daly-Smith is a reader in physical activity and healthy childhood. He leads the Wolfson centre for applied research health childhood theme. His resea…
Source: www.youtube.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0Similar response to omalizumab in children with allergic asthma from different racial backgrounds - 7 month(s) ago
Racial and ethnic minority populations in the United States, especially Black children, endure an increased burden of asthma due to factors such as environmental exposure, access to health care, and genetics.1 Compared with White children, Black children with asthma experience reduced quality of life, have more poorly controlled disease, require longer-term corticosteroid use, and are more frequently evaluated in emergency department visits.1 In addition, Black children are 3 times as likely to be hospitalized and 7 times as likely to die from asthma as White children.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0
Dr. Richard Towne is a licensed pharmacist and doctor of pharmacy (PharmD) graduate from the University of Buffalo School of Pharmacy and Pharmaceutical Sciences. Before joining the Antidote team, he gained patient engagement experience in several settings, including primary care, managed care, hospital, and community pharmacy. He leads the annotation team at Antidote, which is responsible for…
Source: ZoomCategories: Latest Headlines, RheumatologyTweet-
On September 19, join us for a webinar, #Pediatric Clinical Trials 101: What they are and how to participate. Hear from Richard Towne, PharmD, RPh, as he breaks down all aspects of a clinical trial for parents of #children living with pain. https://t.co/7ZHQFJLV24 #PainTrials https://t.co/59815FBA74
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Mashup Score: 2Lipoprotein(a) and subclinical vascular disease progression in children with familial hypercholesterolaemia - 8 month(s) ago
Lipoprotein(a) is a cholesterol-rich particle, high concentrations of which are associated with a greater risk of atherosclerosis and occurrence of aortic valve calcification in the general population.1 This might also be the case for adults affected by familial hypercholesterolaemia,2 a disease in which autosomal dominant genetic defects cause elevated LDL-cholesterol.3–5
Source: www.thelancet.comCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 1Nutrition and Intestinal Rehabilitation of Children With... : Journal of Pediatric Gastroenterology and Nutrition - 8 month(s) ago
is condition. All members of the Nutrition Committee of the European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) contributed to this position paper. Some renowned experts in the field joined the team to guide with their experience. A systematic literature search was performed from 2005 to May 2021 using PubMed, MEDLINE, and Cochrane Database of Systematic Reviews. In the absence of evidence, recommendations reflect the expert opinion of the authors. Literature on SBS mainly consists of retrospective single-center experience, thus most of the current papers and recommendations are based on expert opinion. All recommendations were voted on by the expert panel and reached >90% agreement. The first part of this position paper focuses on the physiological mechanism of intestinal adaptation after surgical resection. It subsequently provides some clinical practice recommendations for the primary management of children with SBS from surgical resection until disch
Source: journals.lww.comCategories: Latest Headlines, PediatricsTweet
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Mashup Score: 3Controversies in Allergy: Are Biologic Treatment Responses in Severe Asthma the Same in Adults and Children? - 8 month(s) ago
The availability of biologic agents for patients with severe asthma has increased dramatically over the last several decades. The absence of direct head-to-head comparative data and relative lack of biomarkers to predict response can make it difficult to choose the right biologic medication for a given patient. Selecting a biologic agent for the pediatric population presents further challenges due to more limited approved biologic agents and fewer clinical trials in children. In addition, the outcome data that are currently available suggest that treatment responses for a given biologic may be different between adult and pediatric patients.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 2The Kids Are Still Not Alright : AJN The American Journal of Nursing - 8 month(s) ago
We have a crisis in child and adolescent health in this country.
Source: journals.lww.comCategories: General Medicine News, Latest HeadlinesTweet
@DAICeditor @DiannaMilewicz @UTHealthHouston A discovery of a mutation in the gene #ACTA2 has given researchers insight into understanding the cause of a rare and progressive problem with #arteries in the brain and a cause of #strokes in young #children: https://t.co/ScCWxejCDG