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Mashup Score: 1Cephalosporins can be safely administered to patients with verified penicillin allergy - 7 month(s) ago
Whereas reported penicillin allergy is highly prevalent, true allergy is rare. Nonetheless, a reported penicillin allergy is associated with higher rates of alternative broad-spectrum antibiotic use, multidrug-resistant infections, surgical site infections, and higher health care costs and mortality.1,2 Although historically cephalosporins have been avoided in reported penicillin allergy, recent literature supports the safety of its administration in this patient population. In alignment with this understanding, Khan et al1 suggested that patients with nonanaphylactic unverified penicillin allergies can receive cephalosporins without testing, and patients with a history of anaphylaxis to penicillin can be given cephalosporins with structurally dissimilar R1 side chains without testing.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 1Why Was There Ever a Warning Not to Use Cephalosporins in the Setting of a Penicillin “Allergy”? - 3 year(s) ago
It is now well-established that avoiding β-lactam antibiotics, when they are the drugs of choice, results in significantly worse long-term global outcomes for patients. Much of this avoidable morbidity has been caused by widespread warnings in electronic health care record systems not to use cephalosporins in the setting of penicillin allergy. High rates, up to 1000-fold higher than now seen, of…
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 2
Avoidance of cephalosporins and penicillin with beta-lactamase inhibitors during anti-TNF therapy reduced the risk for anti-drug antibodies among patients with inflammatory bowel disease, according to research published in Gut. “Primary non-response to anti-TNF therapy is seen in 40% of patients with even higher rates of failure to achieve complete remission. Additionally, the rate of
Source: www.healio.comCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 1Why was there ever a warning not to use cephalosporins in the setting of a penicillin “allergy”? - 3 year(s) ago
It is now well established that avoiding β-lactam antibiotics, when they are the drugs of choice, results in significantly worse long-term global outcomes for patients. Much of this avoidable morbidity has been caused by wide-spread warnings in electronic healthcare record systems not to use cephalosporins in the setting of penicillin “allergy”. High rates, up to 1000-fold higher than now seen,…
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0
The study authors looked at previously published papers focused on carbapenems, fluoroquinolones, and third-generation cephalosporins.
Source: Contagion LiveCategories: Infectious Disease, Latest HeadlinesTweet
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Mashup Score: 0NEJM Journal Watch: Summaries of and commentary on original medical and scientific articles from key medical journals - 3 year(s) ago
NEJM Journal Watch reviews over 250 scientific and medical journals to present important clinical research findings and insightful commentary
Source: www.jwatch.orgCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 1Immediate Reactions to Cephalosporins: It is Time to Standardize the Diagnostic Essence - 3 year(s) ago
A recent European survey discloses cephalosporins to account for 10% to 40% of β-lactam hypersensitivity reactions, with ceftriaxone, cefaclor, and cefuroxime most commonly involved.1 Of the 333 cases of drug-induced anaphylaxis registered in Europe between 2002 and 2010, 12.3% were attributable to cephalosporins.1 According to a US-based health-record database, cephalosporins accounted for 4% of…
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Mashup Score: 0
Few studies have assessed the diagnostic value of cephalosporin skin tests in patients with immediate reactions to these β-lactams.
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0
These commonly prescribed antibiotics come with the risk of serious adverse effects.
Source: MDLinxCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0Testing Strategies and Predictors for Evaluating Immediate and Delayed Reactions to Cephalosporins - 3 year(s) ago
Although 1% to 2% of the general population carries a cephalosporin allergy label (CAL), we lack validated testing strategies and predictors of true allergy.
Categories: Allergy-Immunology, Latest HeadlinesTweet
In Current Issue! #Cephalosporins can be #safely administered to #patients with verified #penicillin #allergy https://t.co/edpLk0bYJo https://t.co/6uImEDcWmq