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Mashup Score: 7
Frontline treatment of chronic lymphocytic leukemia (CLL) with a Bruton tyrosine kinase inhibitor (BTKi) has largely replaced chemoimmunotherapy, with
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Mashup Score: 1Postpartum Blood Pressure Control in Hypertensive Disorders of Pregnancy: Is Lower Better? - 3 day(s) ago
Current U.S. guidelines recommend postpartum antihypertensive therapy once blood pressure (BP) exceeds 150/100 mm Hg. In this observational study,
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Mashup Score: 2
The first symptoms of Parkinson disease (PD) have been referred to by many experts as prodromal. In this study from a cohort of 51,529 U.S.-based male
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Mashup Score: 0How Safe Is Metformin in Stage 4 Chronic Kidney Disease? - 14 day(s) ago
Metformin is excreted renally and is contraindicated (according to U.S. prescribing information) in patients with estimated glomerular filtration rates
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Mashup Score: 4Can ChatGPT Enhance Physicians' Decision Making? - 15 day(s) ago
Large language models (LLMs), such as ChatGPT, perform well in diagnostic reasoning (NEJM JW Gen Med Jan 15 2025), but their ability to balance testing
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Mashup Score: 2
Out-of-office self-measured blood pressure (BP) monitoring is recommended widely by U.S. guidelines for managing hypertension. International guidelines
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Mashup Score: 1
Primary pulmonary coccidioidomycosis typically resolve without treatment, but some patients have persistent symptoms, and a small percentage later
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Mashup Score: 3Are Antibiotics a Reasonable Alternative for Uncomplicated Appendicitis in Children? - 20 day(s) ago
In recent trials, researchers have explored antibiotic therapy for uncomplicated appendicitis as an alternative to appendectomy in adults, but large
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Mashup Score: 0All-Oral Shortened Regimens for Treatment of Drug-Resistant TB - 23 day(s) ago
Patients with rifampin-resistant tuberculosis (TB) have traditionally been treated with 18- to 24-month regimens that include injectable drugs, but
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Mashup Score: 5Does Postdischarge Contact Lower Healthcare Use? - 24 day(s) ago
One third of hospitalized patients visit the emergency department in the 30 days after discharge. To evaluate whether postdischarge contact by
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A phase 3 trial in @NEJM compared fixed-duration acalabrutinib combinations against chemoimmunotherapy in previously untreated patients with chronic lymphocytic leukemia. https://t.co/BxgdskSjQ5 https://t.co/3VSg4vrXoT