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Mashup Score: 1Prevalence of Antiphospholipid Antibodies and Association With Incident Cardiovascular Events - 1 year(s) ago
This cohort study examines the association between measurements of antiphospholipid antibodies (aPL) at a single time point and atherosclerotic cardiovascular disease risk in a diverse population.
Source: jamanetwork.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 7Infection with wild-type SARS-CoV-2 elicits broadly neutralizing and protective antibodies against omicron subvariants - Nature Immunology - 1 year(s) ago
Zhang and colleagues perform functional, biochemical and structural analysis of a set of antibodies isolated from COVID-19 convalescents infected with wild-type SARS-CoV-2 during the first wave of the pandemic and show they have broad neutralizing activity against all SARS-CoV-2 variants tested, including omicron.
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 3Importance, Applications and Features of Assays Measuring SARS-CoV-2 Neutralizing Antibodies - 1 year(s) ago
More than three years ago, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) caused the unforeseen COVID-19 pandemic with millions of deaths. In the meantime, SARS-CoV-2 has become endemic and is now part of the repertoire of viruses causing seasonal severe respiratory infections. Due to several factors, among them the development of SARS-CoV-2 immunity through natural infection,…
Source: MDPICategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0Intermediate Levels of Pre-Existing Protective Antibody Allow Priming of Protective T Cell Immunity against Influenza - 1 year(s) ago
Key Points. A range of transferred IAV-specific Abs protects mice from lethal homotypic IAV.Detectable IAV-specific T cell priming occurs in the presence of pre
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0Ataxia Telangiectasia Mutated and MSH2 Control Blunt DNA End Joining in Ig Class Switch Recombination - 1 year(s) ago
Key Points. Loss of DNA repair genes Atm and Msh2 produces, to our knowledge, a novel synthetic lethality in mice.Deletion of Atm and Msh2 in B cells reduces Ig
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0Incidence of Anti-Drug Antibodies to Monoclonal Antibodies in Asthma: A Systematic Review and Meta-Analysis - 1 year(s) ago
Anti-drug antibodies (ADA) may worsen the efficacy and safety of biologics. However, little is known about the incidence of ADAs associated with the six biologics approved for the treatment of asthma in the US.
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 6Hyperimmune immunoglobulin for people with COVID‐19 - Kimber, C - 2023 | Cochrane Library - 1 year(s) ago
Collapse all Expand all Background Hyperimmune immunoglobulin (hIVIG) contains polyclonal antibodies, which can be prepared from large amounts of pooled convalescent plasma or prepared from animal sources through immunisation. They are being investigated as a potential therapy for coronavirus disease 2019 (COVID‐19). This review was previously part of a parent review addressing…
Source: www.cochranelibrary.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 3Hyperimmune immunoglobulin for people with COVID‐19 - Kimber, C - 2023 | Cochrane Library - 1 year(s) ago
Collapse all Expand all Background Hyperimmune immunoglobulin (hIVIG) contains polyclonal antibodies, which can be prepared from large amounts of pooled convalescent plasma or prepared from animal sources through immunisation. They are being investigated as a potential therapy for coronavirus disease 2019 (COVID‐19). This review was previously part of a parent review addressing…
Source: www.cochranelibrary.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 8
A team of researchers affiliated with multiple institutions in Switzerland and Germany has found that antibodies that heal the brain after a stroke can be delivered via nasal spray in mice. Their study was published in Proceedings of the National Academy of Sciences.
Source: medicalxpress.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 8Duping antibodies with a decoy, researchers aim to prevent rejection of transplanted cells - 1 year(s) ago
Researchers at UCSF have developed a novel, potentially life-saving approach that may prevent antibodies from triggering immune rejection of engineered therapeutic and transplant cells.
Source: medicalxpress.comCategories: General Medicine News, Latest HeadlinesTweet
Antiphospholipid #antibodies may increase #heart disease risk in healthy people @umich @jamanetworkopen https://t.co/UIbLRlj5Eb https://t.co/hEya7SGqMk